# Dynamin 1 like

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21101107](https://www.wikidata.org/wiki/Q21101107)  
**Source**: https://4ort.xyz/entity/dynamin-1-like


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/O00429)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00429)
5. [Mff is an essential factor for mitochondrial recruitment of Drp1 during mitochondrial fission in mammalian cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00429)
6. [Human Dynamin-like Protein Interacts with the Glycogen Synthase Kinase 3β](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00429)
7. [The mitochondrial protein hFis1 regulates mitochondrial fission in mammalian cells through an interaction with the dynamin-like protein DLP1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00429)
8. [Human MIEF1 recruits Drp1 to mitochondrial outer membranes and promotes mitochondrial fusion rather than fission](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00429)
9. [MiD49 and MiD51, new components of the mitochondrial fission machinery](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00429)
10. [SUMOylation of the mitochondrial fission protein Drp1 occurs at multiple nonconsensus sites within the B domain and is linked to its activity cycle](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00429)
11. [Fis1, Mff, MiD49, and MiD51 mediate Drp1 recruitment in mitochondrial fission](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00429)
12. [Dephosphorylation by calcineurin regulates translocation of Drp1 to mitochondria](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00429)
13. [Parkinson's disease-associated mutant VPS35 causes mitochondrial dysfunction by recycling DLP1 complexes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00429)
14. [Abnormal interaction between the mitochondrial fission protein Drp1 and hyperphosphorylated tau in Alzheimer's disease neurons: implications for mitochondrial dysfunction and neuronal damage](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00429)
15. [RAC3 is a pro-migratory co-activator of ERα](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00429)
16. [Leucine-rich repeat kinase 2 disturbs mitochondrial dynamics via Dynamin-like protein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00429)
17. [Inhibition of excessive mitochondrial fission reduced aberrant autophagy and neuronal damage caused by LRRK2 G2019S mutation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00429)
18. [Functional interaction of Parkinson's disease-associated LRRK2 with members of the dynamin GTPase superfamily](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00429)
19. [Large-scale interaction profiling of PDZ domains through proteomic peptide-phage display using human and viral phage peptidomes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00429)
20. [LRRK2 regulates mitochondrial dynamics and function through direct interaction with DLP1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00429)
21. [SAMM50 Affects Mitochondrial Morphology through the Association of Drp1 in Mammalian Cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00429)
22. [MAPL is a new mitochondrial SUMO E3 ligase that regulates mitochondrial fission](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00429)
23. [A novel mitochondrial ubiquitin ligase plays a critical role in mitochondrial dynamics](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00429)
24. [Interaction with the effector dynamin-related protein 1 (Drp1) is an ancient function of Rab32 subfamily proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00429)
25. [The mitochondrial phosphatase PGAM5 functions at the convergence point of multiple necrotic death pathways](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00429)
26. [Interchangeable adaptors regulate mitochondrial dynamin assembly for membrane scission](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00429)
27. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00429)
28. [Dynamin-like protein 1 at the Golgi complex: A novel component of the sorting/targeting machinery en route to the plasma membrane](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00429)
29. [Adaptor proteins MiD49 and MiD51 can act independently of Mff and Fis1 in Drp1 recruitment and are specific for mitochondrial fission](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00429)
30. [The dynamin-like GTPase DLP1 is essential for peroxisome division and is recruited to peroxisomes in part by PEX11](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00429)
31. [A novel de novo dominant negative mutation in DNM1L impairs mitochondrial fission and presents as childhood epileptic encephalopathy](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00429)
32. [Signal transducer and activator of transcription 2 deficiency is a novel disorder of mitochondrial fission](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00429)
33. [A Novel Dynamin-like Protein Associates with Cytoplasmic Vesicles and Tubules of the Endoplasmic Reticulum in Mammalian Cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00429)
34. [Mutations in DNM1L, as in OPA1, result indominant optic atrophy despite opposite effectson mitochondrial fusion and fission](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00429)
35. [An Actin-Dependent Step in Mitochondrial Fission Mediated by the ER-Associated Formin INF2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00429)
36. [Vps13D Encodes a Ubiquitin-Binding Protein that Is Required for the Regulation of Mitochondrial Size and Clearance.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00429)
37. [Dynamin-related protein Drp1 is required for mitochondrial division in mammalian cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00429)
38. [Phosphatidic Acid (PA)-preferring Phospholipase A1 Regulates Mitochondrial Dynamics](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00429)
39. [Defining the membrane proteome of NK cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00429)
40. [Fis1, DLP1, and Pex11p coordinately regulate peroxisome morphogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00429)
41. [Identification and functional characterization of a novel human protein highly related to the yeast dynamin-like GTPase Vps1p](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00429)
42. [Membrane remodeling induced by the dynamin-related protein Drp1 stimulates Bax oligomerization](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00429)
43. [The novel tail-anchored membrane protein Mff controls mitochondrial and peroxisomal fission in mammalian cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00429)
44. [Postnatal microcephaly and pain insensitivity due to a de novo heterozygous DNM1L mutation causing impaired mitochondrial fission and function](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00429)
45. [Dynamin-related protein Drp1 is required for mitochondrial division in mammalian cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=O00429&geneProductId=UniProtKB:O00429)
46. [Spatial and temporal association of Bax with mitochondrial fission sites, Drp1, and Mfn2 during apoptosis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00429)
47. [The BH3-only Bnip3 binds to the dynamin Opa1 to promote mitochondrial fragmentation and apoptosis by distinct mechanisms](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00429)
48. [Loss of PINK1 function promotes mitophagy through effects on oxidative stress and mitochondrial fission](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00429)
49. [Biallelic Mutations in DNM1L are Associated with a Slowly Progressive Infantile Encephalopathy](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00429)
50. [DNM1L-related encephalopathy in infancy with Leigh syndrome-like phenotype and suppression-burst](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00429)