# Dynactin subunit 1

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21105413](https://www.wikidata.org/wiki/Q21105413)  
**Source**: https://4ort.xyz/entity/dynactin-subunit-1


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q14203)
3. Q20641742
4. [Par6 alpha interacts with the dynactin subunit p150 Glued and is a critical regulator of centrosomal protein recruitment](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14203)
5. [HPS6 interacts with dynactin p150Glued to mediate retrograde trafficking and maturation of lysosomes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14203)
6. [Polo-like kinase 1 phosphorylation of p150 Glued facilitates nuclear envelope breakdown during prophase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14203)
7. [The retromer component SNX6 interacts with dynactin p150(Glued) and mediates endosome-to-TGN transport](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14203)
8. [Characterization of the p22 Subunit of Dynactin Reveals the Localization of Cytoplasmic Dynein and Dynactin to the Midbody of Dividing Cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14203)
9. [A Novel Human Dynactin-Associated Protein, dynAP, Promotes Activation of Akt, and Ergosterol-Related Compounds Induce dynAP-Dependent Apoptosis of Human Cancer Cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14203)
10. [The Bardet-Biedl protein BBS4 targets cargo to the pericentriolar region and is required for microtubule anchoring and cell cycle progression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14203)
11. [FBXL5 interacts with p150Glued and regulates its ubiquitination](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14203)
12. [The retromer coat complex coordinates endosomal sorting and dynein-mediated transport, with carrier recognition by the trans-Golgi network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14203)
13. [α-Tubulin Tyrosination and CLIP-170 Phosphorylation Regulate the Initiation of Dynein-Driven Transport in Neurons](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14203)
14. [Regulation of spindle integrity and mitotic fidelity by BCCIP](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14203)
15. [Linking cytoplasmic dynein and transport of Rab8 vesicles to the midbody during cytokinesis by the doublecortin domain-containing 5 protein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14203)
16. [The centriolar satellite protein Cep131 is important for genome stability](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14203)
17. [The novel actin/focal adhesion-associated protein MISP is involved in mitotic spindle positioning in human cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14203)
18. [Huntingtin regulates RE1-silencing transcription factor/neuron-restrictive silencer factor (REST/NRSF) nuclear trafficking indirectly through a complex with REST/NRSF-interacting LIM domain protein (RILP) and dynactin p150 Glued](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14203)
19. [Nucleoporin translocated promoter region (Tpr) associates with dynein complex, preventing chromosome lagging formation during mitosis.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14203)
20. [CLIP170 autoinhibition mimics intermolecular interactions with p150Glued or EB1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14203)
21. [Dynactin subunit p150(Glued) is a neuron-specific anti-catastrophe factor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14203)
22. [Cep126 is required for pericentriolar satellite localisation to the centrosome and for primary cilium formation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14203)
23. [Tubulin-binding cofactor B is a direct interaction partner of the dynactin subunit p150Glued](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14203)
24. [Neuronal ceroid lipofuscinosis protein CLN3 interacts with motor proteins and modifies location of late endosomal compartments](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14203)
25. [PtdIns(4)P regulates retromer-motor interaction to facilitate dynein-cargo dissociation at the trans-Golgi network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14203)
26. [Interaction of tau protein with the dynactin complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14203)
27. [Reconstitution of a hierarchical +TIP interaction network controlling microtubule end tracking of dynein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14203)
28. [Structure-function relationship of CAP-Gly domains](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14203)
29. [A Dynamic Protein Interaction Landscape of the Human Centrosome-Cilium Interface](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14203)
30. [Huntingtin-associated protein 1 (HAP1) interacts with the p150Glued subunit of dynactin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14203)
31. [An organelle-specific protein landscape identifies novel diseases and molecular mechanisms](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14203)
32. [The Human Tau Interactome: Binding to the Ribonucleoproteome, and Impaired Binding of the Proline-to-Leucine Mutant at Position 301 (P301L) to Chaperones and the Proteasome](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14203)
33. [Interactions between the evolutionarily conserved, actin-related protein, Arp11, actin, and Arp1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14203)
34. [A human interactome in three quantitative dimensions organized by stoichiometries and abundances](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14203)
35. [Huntingtin phosphorylation acts as a molecular switch for anterograde/retrograde transport in neurons](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14203)
36. [Novel interaction partners of Bardet-Biedl syndrome proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14203)
37. [The herpesvirus VP1/2 protein is an effector of dynein-mediated capsid transport and neuroinvasion](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14203)
38. [GSK-3beta-regulated interaction of BICD with dynein is involved in microtubule anchorage at centrosome](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14203)
39. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14203)
40. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14203&geneProductId=UniProtKB:Q14203)
41. [α-Tubulin Tyrosination and CLIP-170 Phosphorylation Regulate the Initiation of Dynein-Driven Transport in Neurons](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14203&geneProductId=UniProtKB:Q14203)
42. [Dynactin subunit p150(Glued) is a neuron-specific anti-catastrophe factor](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14203&geneProductId=UniProtKB:Q14203)
43. [A motor neuron disease-associated mutation in p150Glued perturbs dynactin function and induces protein aggregation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14203)
44. [Roles of tau protein in health and disease](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14203)
45. [Homology of a 150K cytoplasmic dynein-associated polypeptide with the Drosophila gene Glued](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14203&geneProductId=UniProtKB:Q14203)
46. [Cell Cycle‐Dependent Localization of Dynactin Subunit p150glued at Centrosome](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14203)
47. [Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14203)
48. [Ste20-like protein kinase SLK (LOSK) regulates microtubule organization by targeting dynactin to the centrosome](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14203)
49. [Defining the membrane proteome of NK cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q14203&geneProductId=UniProtKB:Q14203)
50. [PEX14 is required for microtubule-based peroxisome motility in human cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q14203)