# Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1a

> mammalian protein found in Mus musculus

**Wikidata**: [Q21981053](https://www.wikidata.org/wiki/Q21981053)  
**Source**: https://4ort.xyz/entity/dual-specificity-tyrosine-y-phosphorylation-regulated-kinase-1a


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q61214)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61214)
5. [Sequence characteristics, subcellular localization, and substrate specificity of DYRK-related kinases, a novel family of dual specificity protein kinases](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61214)
6. [The murine Dyrk protein maps to chromosome 16, localizes to the nucleus, and can form multimers](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61214)
7. [DYRK1A and glycogen synthase kinase 3beta, a dual-kinase mechanism directing proteasomal degradation of CRY2 for circadian timekeeping](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61214)
8. [Dyrk1A potentiates steroid hormone-induced transcription via the chromatin remodeling factor Arip4](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61214)
9. [Regulation of the alternative splicing of tau exon 10 by SC35 and Dyrk1A](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61214)
10. [DYRK1A and DYRK3 promote cell survival through phosphorylation and activation of SIRT1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61214)
11. [Regulation of RCAN1 protein activity by Dyrk1A protein-mediated phosphorylation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61214)
12. [Direct association of Sprouty-related protein with an EVH1 domain (SPRED) 1 or SPRED2 with DYRK1A modifies substrate/kinase interactions](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61214)
13. [DYRK1A-mediated hyperphosphorylation of Tau. A functional link between Down syndrome and Alzheimer disease](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61214)
14. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61214&geneProductId=UniProtKB:Q61214)
15. [DYRK1A and glycogen synthase kinase 3beta, a dual-kinase mechanism directing proteasomal degradation of CRY2 for circadian timekeeping](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61214&geneProductId=UniProtKB:Q61214)
16. [Direct association of Sprouty-related protein with an EVH1 domain (SPRED) 1 or SPRED2 with DYRK1A modifies substrate/kinase interactions](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61214&geneProductId=UniProtKB:Q61214)
17. [Form of dual-specificity tyrosine-(Y)-phosphorylation-regulated kinase 1A nonphosphorylated at tyrosine 145 and 147 is enriched in the nuclei of astroglial cells, adult hippocampal progenitors, and some cholinergic axon terminals](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61214)
18. [Form of dual-specificity tyrosine-(Y)-phosphorylation-regulated kinase 1A nonphosphorylated at tyrosine 145 and 147 is enriched in the nuclei of astroglial cells, adult hippocampal progenitors, and some cholinergic axon terminals](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q61214&geneProductId=UniProtKB:Q61214)
19. [Intracellular distribution of differentially phosphorylated dual‐specificity tyrosine phosphorylation‐regulated kinase 1A (DYRK1A)](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61214)
20. [Dephosphorylation of the nuclear factor of activated T cells (NFAT) transcription factor is regulated by an RNA-protein scaffold complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q61214)
21. ensembl Release 106