# Dual specificity tyrosine phosphorylation regulated kinase 1A

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21101022](https://www.wikidata.org/wiki/Q21101022)  
**Source**: https://4ort.xyz/entity/dual-specificity-tyrosine-phosphorylation-regulated-kinase-1a


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q13627)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13627)
5. [Isolation of human and murine homologues of the Drosophila minibrain gene: human homologue maps to 21q22.2 in the Down syndrome "critical region"](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13627)
6. [Cloning of a human homolog of the Drosophila minibrain/rat Dyrk gene from "the Down syndrome critical region" of chromosome 21](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13627)
7. [Sequence characteristics, subcellular localization, and substrate specificity of DYRK-related kinases, a novel family of dual specificity protein kinases](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13627)
8. [Cloning of a human homolog of the Drosophila minibrain/rat Dyrk gene from "the Down syndrome critical region" of chromosome 21](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13627&geneProductId=UniProtKB:Q13627)
9. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13627&geneProductId=UniProtKB:Q13627)
10. [Direct association of Sprouty-related protein with an EVH1 domain (SPRED) 1 or SPRED2 with DYRK1A modifies substrate/kinase interactions](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13627&geneProductId=UniProtKB:Q13627)
11. [Dual-specificity tyrosine-phosphorylated and regulated kinase 1A (DYRK1A) interacts with the phytanoyl-CoA alpha-hydroxylase associated protein 1 (PAHX-AP1), a brain specific protein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13627)
12. [Phosphorylation of Ser640 in Muscle Glycogen Synthase by DYRK Family Protein Kinases](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13627)
13. [Serine/Threonine Kinase Mirk/Dyrk1B Is an Inhibitor of Epithelial Cell Migration and Is Negatively Regulated by the Met Adaptor Ran-binding Protein M](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13627)
14. [The protein interaction landscape of the human CMGC kinase group](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13627)
15. [A High-Density Map for Navigating the Human Polycomb Complexome](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13627)
16. [An organelle-specific protein landscape identifies novel diseases and molecular mechanisms](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13627)
17. [The WD40-repeat protein Han11 functions as a scaffold protein to control HIPK2 and MEKK1 kinase functions](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13627)
18. [Direct association of Sprouty-related protein with an EVH1 domain (SPRED) 1 or SPRED2 with DYRK1A modifies substrate/kinase interactions](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13627)
19. [Structures of Down Syndrome Kinases, DYRKs, Reveal Mechanisms of Kinase Activation and Substrate Recognition](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13627&geneProductId=UniProtKB:Q13627)
20. [Roles of tau protein in health and disease](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13627)
21. [A novel DYRK1A (dual specificity tyrosine phosphorylation-regulated kinase 1A) inhibitor for the treatment of Alzheimer's disease: effect on Tau and amyloid pathologies in vitro.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13627)
22. [DYRK1A-mediated hyperphosphorylation of Tau. A functional link between Down syndrome and Alzheimer disease](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13627)
23. [The murine Dyrk protein maps to chromosome 16, localizes to the nucleus, and can form multimers](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13627)
24. [Dual specificity kinase DYRK3 couples stress granule condensation/dissolution to mTORC1 signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13627)
25. [Intracellular distribution of differentially phosphorylated dual‐specificity tyrosine phosphorylation‐regulated kinase 1A (DYRK1A)](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13627&geneProductId=UniProtKB:Q13627)
26. [Intracellular distribution of differentially phosphorylated dual‐specificity tyrosine phosphorylation‐regulated kinase 1A (DYRK1A)](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13627)
27. [Dyrk1A overexpression leads to increase of 3R-tau expression and cognitive deficits in Ts65Dn Down syndrome mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13627)
28. Ensembl Release 99