# DOT1 like histone lysine methyltransferase

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21116404](https://www.wikidata.org/wiki/Q21116404)  
**Source**: https://4ort.xyz/entity/dot1-like-histone-lysine-methyltransferase


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q8TEK3)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TEK3)
5. [A Novel Disrupter of Telomere Silencing 1-like (DOT1L) Interaction Is Required for Signal Transducer and Activator of Transcription 1 (STAT1)-activated Gene Expression](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8TEK3&geneProductId=UniProtKB:Q8TEK3)
6. [A higher-order complex containing AF4 and ENL family proteins with P-TEFb facilitates oncogenic and physiologic MLL-dependent transcription](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TEK3)
7. [A human interactome in three quantitative dimensions organized by stoichiometries and abundances](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TEK3)
8. [Linking H3K79 trimethylation to Wnt signaling through a novel Dot1-containing complex (DotCom)](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TEK3)
9. [Leukemia fusion target AF9 is an intrinsically disordered transcriptional regulator that recruits multiple partners via coupled folding and binding.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TEK3)
10. [hDOT1L links histone methylation to leukemogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TEK3)
11. [Modulation of p53 function by SET8-mediated methylation at lysine 382](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TEK3)
12. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8TEK3&geneProductId=UniProtKB:Q8TEK3)
13. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TEK3)
14. [hDOT1L links histone methylation to leukemogenesis](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8TEK3&geneProductId=UniProtKB:Q8TEK3)
15. [A charge-based interaction between histone H4 and Dot1 is required for H3K79 methylation and telomere silencing: identification of a new trans-histone pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TEK3)
16. [A Novel Disrupter of Telomere Silencing 1-like (DOT1L) Interaction Is Required for Signal Transducer and Activator of Transcription 1 (STAT1)-activated Gene Expression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8TEK3)
17. Ensembl Release 99