# DNA topoisomerase III alpha

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21121455](https://www.wikidata.org/wiki/Q21121455)  
**Source**: https://4ort.xyz/entity/dna-topoisomerase-iii-alpha


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q13472)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13472)
5. [Human Topoisomerase IIIα Is a Single-stranded DNA Decatenase That Is Stimulated by BLM and RMI1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13472)
6. [Human TOP3: a single-copy gene encoding DNA topoisomerase III.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13472)
7. [Association of the Bloom syndrome protein with topoisomerase IIIalpha in somatic and meiotic cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13472)
8. [Scaffolding protein SPIDR/KIAA0146 connects the Bloom syndrome helicase with homologous recombination repair](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13472)
9. [BLAP75, an essential component of Bloom's syndrome protein complexes that maintain genome integrity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13472)
10. [BLAP75/RMI1 promotes the BLM-dependent dissolution of homologous recombination intermediates](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13472)
11. [Systematic Analysis of Human Protein Complexes Identifies Chromosome Segregation Proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13472)
12. [Rif1 provides a new DNA‐binding interface for the Bloom syndrome complex to maintain normal replication](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13472)
13. [Structural and mechanistic insight into Holliday-junction dissolution by Topoisomerase IIIα and RMI1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13472)
14. [Crystal Structures of RMI1 and RMI2, Two OB-Fold Regulatory Subunits of the BLM Complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13472)
15. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13472&geneProductId=UniProtKB:Q13472)
16. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13472)
17. [Topoisomerase 3α Is Required for Decatenation and Segregation of Human mtDNA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13472)
18. [Human TOP3: a single-copy gene encoding DNA topoisomerase III.](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13472&geneProductId=UniProtKB:Q13472)
19. [Human Topoisomerase IIIα Is a Single-stranded DNA Decatenase That Is Stimulated by BLM and RMI1](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13472&geneProductId=UniProtKB:Q13472)
20. [Mutations in TOP3A Cause a Bloom Syndrome-like Disorder](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13472)
21. Ensembl Release 99