# DNA topoisomerase II beta

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21121454](https://www.wikidata.org/wiki/Q21121454)  
**Source**: https://4ort.xyz/entity/dna-topoisomerase-ii-beta


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q02880)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02880)
5. [Mutagenesis of E477 or K505 in the B' domain of human topoisomerase II beta increases the requirement for magnesium ions during strand passage](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02880)
6. [Deacetylase activity associates with topoisomerase II and is necessary for etoposide-induced apoptosis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02880)
7. [Histone deacetylase interacts directly with DNA topoisomerase II](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02880)
8. [Cell cycle-coupled relocation of types I and II topoisomerases and modulation of catalytic enzyme activities](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02880)
9. [Human topoisomerase IIalpha and IIbeta interact with the C-terminal region of p53](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02880)
10. [Using a biochemical approach to identify the primary dimerization regions in human DNA topoisomerase IIalpha](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02880)
11. [Nuclear interactions of topoisomerase II alpha and beta with phospholipid scramblase 1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02880)
12. [Protein kinase C delta activates topoisomerase IIalpha to induce apoptotic cell death in response to DNA damage](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02880)
13. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02880&geneProductId=UniProtKB:Q02880)
14. [Nuclear interactions of topoisomerase II alpha and beta with phospholipid scramblase 1](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02880&geneProductId=UniProtKB:Q02880)
15. [Cell cycle-coupled relocation of types I and II topoisomerases and modulation of catalytic enzyme activities](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02880&geneProductId=UniProtKB:Q02880)
16. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02880)
17. [A study of the topoisomerase II activity in HIV-1 replication using the ferrocene derivatives as probes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02880)
18. Ensembl Release 99