# DNA topoisomerase II alpha

> mammalian protein found in Rattus norvegicus

**Wikidata**: [Q28560144](https://www.wikidata.org/wiki/Q28560144)  
**Source**: https://4ort.xyz/entity/dna-topoisomerase-ii-alpha


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P41516)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41516)
5. [Nucleotide sequence analysis of the CDNA for rat DNA topoisomerase II](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41516)
6. [Substrate specificity plays an important role in uncoupling the catalytic and scaffolding activities of rat testis DNA topoisomerase IIalpha](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41516)
7. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41516)
8. [Immunohistochemical analyses of DNA topoisomerase II isoforms in developing rat cerebellum](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41516)
9. [Differential expressions of the topoisomerase II alpha and II beta mRNAs in developing rat brain](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41516)
10. [Gene expression changes are age-dependent and lobe-specific in the brown Norway rat model of prostatic hyperplasia](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41516)
11. [Glucose-regulated protein 75 overexpression attenuates ionizing radiation-mediated injury in PC12 cells by inducing the expression of topoisomerase IIα](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41516)
12. [The expression of the nuclear matrix proteins NuMA, topoisomerase II-alpha, and -beta in bone and osseous cell culture: regulation by parathyroid hormone](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41516)
13. ensembl Release 106