# DNA topoisomerase 2 YNL088W

> fungal protein found in Saccharomyces cerevisiae S288c

**Wikidata**: [Q27547626](https://www.wikidata.org/wiki/Q27547626)  
**Source**: https://4ort.xyz/entity/dna-topoisomerase-2-ynl088w


## References

1. UniProt
2. Q20641742
3. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P06786)
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06786)
5. [Yeast DNA topoisomerase II is encoded by a single-copy, essential gene](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06786)
6. [The purification and characterization of DNA topoisomerases I and II of the yeast Saccharomyces cerevisiae](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06786)
7. [The identification of a functional interaction between PKC and topoisomerase II.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06786)
8. [Structure of a topoisomerase II–DNA–nucleotide complex reveals a new control mechanism for ATPase activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06786)
9. [Structural basis for gate-DNA recognition and bending by type IIA topoisomerases](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06786)
10. [A novel and unified two-metal mechanism for DNA cleavage by type II and IA topoisomerases](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06786)
11. [Structure and mechanism of DNA topoisomerase II](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06786)
12. [Localization of RAP1 and topoisomerase II in nuclei and meiotic chromosomes of yeast](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06786)
13. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P06786&geneProductId=UniProtKB:P06786)
14. [The purification and characterization of DNA topoisomerases I and II of the yeast Saccharomyces cerevisiae](http://www.ebi.ac.uk/QuickGO/annotations?protein=P06786&geneProductId=UniProtKB:P06786)
15. [Replication termination at eukaryotic chromosomes is mediated by Top2 and occurs at genomic loci containing pausing elements](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06786)
16. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?protein=P06786&geneProductId=UniProtKB:P06786)
17. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06786)
18. [Dissecting DNA damage response pathways by analysing protein localization and abundance changes during DNA replication stress](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06786)
19. [Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06786)
20. [DNA topoisomerase II is a determinant of the tensile properties of yeast centromeric chromatin and the tension checkpoint](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06786)
21. [Function of DNA topoisomerases as replication swivels in Saccharomyces cerevisiae](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06786)
22. [Segregation of recombined chromosomes in meiosis I requires DNA topoisomerase II.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06786)
23. [Mitotic recombination in the rDNA of S. cerevisiae is suppressed by the combined action of DNA topoisomerases I and II.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06786)
24. [A mitotic topoisomerase II checkpoint in budding yeast is required for genome stability but acts independently of Pds1/securin.](http://www.ebi.ac.uk/QuickGO/annotations?protein=P06786&geneProductId=UniProtKB:P06786)
25. [A mitotic topoisomerase II checkpoint in budding yeast is required for genome stability but acts independently of Pds1/securin.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06786)
26. ensembl Release 106