# DNA replication initiation factor CDC45 YLR103C

> fungal protein found in Saccharomyces cerevisiae S288c

**Wikidata**: [Q27548055](https://www.wikidata.org/wiki/Q27548055)  
**Source**: https://4ort.xyz/entity/dna-replication-initiation-factor-cdc45-ylr103c


## References

1. UniProt
2. Q20641742
3. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08032)
4. [Mcm10 regulates the stability and chromatin association of DNA polymerase-alpha.](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q08032&geneProductId=UniProtKB:Q08032)
5. [Formation of a Preinitiation Complex by S-phase Cyclin CDK-Dependent Loading of Cdc45p onto Chromatin](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q08032&geneProductId=UniProtKB:Q08032)
6. [Cdc45 protein-single-stranded DNA interaction is important for stalling the helicase during replication stress](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q08032&geneProductId=UniProtKB:Q08032)
7. [The mcm5-bob1 bypass of Cdc7p/Dbf4p in DNA replication depends on both Cdk1-independent and Cdk1-dependent steps in Saccharomyces cerevisiae](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q08032&geneProductId=UniProtKB:Q08032)
8. [Sld7, an Sld3-associated protein required for efficient chromosomal DNA replication in budding yeast](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08032)
9. [Crystal Structure of the Homology Domain of the Eukaryotic DNA Replication Proteins Sld3/Treslin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08032)
10. [Mrc1 phosphorylation in response to DNA replication stress is required for Mec1 accumulation at the stalled fork](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08032)
11. [Defining the budding yeast chromatin‐associated interactome](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08032)
12. [CDK-dependent phosphorylation of Sld2 and Sld3 initiates DNA replication in budding yeast](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08032)
13. [S-phase checkpoint proteins Tof1 and Mrc1 form a stable replication-pausing complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08032)
14. [Checkpoint-dependent inhibition of DNA replication initiation by Sld3 and Dbf4 phosphorylation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08032)
15. [Mcm10 regulates the stability and chromatin association of DNA polymerase-alpha.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08032)
16. [Formation of a Preinitiation Complex by S-phase Cyclin CDK-Dependent Loading of Cdc45p onto Chromatin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08032)
17. [The mcm5-bob1 bypass of Cdc7p/Dbf4p in DNA replication depends on both Cdk1-independent and Cdk1-dependent steps in Saccharomyces cerevisiae](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08032)
18. [Cdc45 protein-single-stranded DNA interaction is important for stalling the helicase during replication stress](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08032)
19. [Components and Dynamics of DNA Replication Complexes in S. cerevisiae: Redistribution of MCM Proteins and Cdc45p during S Phase](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q08032&geneProductId=UniProtKB:Q08032)
20. [Molecular anatomy and regulation of a stable replisome at a paused eukaryotic DNA replication fork.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08032)
21. [GINS maintains association of Cdc45 with MCM in replisome progression complexes at eukaryotic DNA replication forks](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q08032&geneProductId=UniProtKB:Q08032)
22. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08032)
23. [Cdc45p assembles into a complex with Cdc46p/Mcm5p, is required for minichromosome maintenance, and is essential for chromosomal DNA replication](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08032)
24. [The architecture of a eukaryotic replisome.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08032)
25. [Components and Dynamics of DNA Replication Complexes in S. cerevisiae: Redistribution of MCM Proteins and Cdc45p during S Phase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08032)
26. [GINS maintains association of Cdc45 with MCM in replisome progression complexes at eukaryotic DNA replication forks](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08032)
27. [Break-induced replication requires all essential DNA replication factors except those specific for pre-RC assembly.](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q08032&geneProductId=UniProtKB:Q08032)
28. [A group of interacting yeast DNA replication genes](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q08032&geneProductId=UniProtKB:Q08032)
29. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q08032&geneProductId=UniProtKB:Q08032)
30. [Break-induced replication requires all essential DNA replication factors except those specific for pre-RC assembly.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08032)
31. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q08032&geneProductId=UniProtKB:Q08032)
32. [A group of interacting yeast DNA replication genes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q08032)
33. ensembl Release 106