# DNA methyltransferase (cytosine-5) 1

> mammalian protein found in Mus musculus

**Wikidata**: [Q14908005](https://www.wikidata.org/wiki/Q14908005)  
**Source**: https://4ort.xyz/entity/dna-methyltransferase-cytosine-5-1


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P13864)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13864)
5. [DNA methyltransferase Dnmt1 associates with histone deacetylase activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13864)
6. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P13864&geneProductId=UniProtKB:P13864)
7. [The activity of the murine DNA methyltransferase Dnmt1 is controlled by interaction of the catalytic domain with the N-terminal part of the enzyme leading to an allosteric activation of the enzyme after binding to methylated DNA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P13864&geneProductId=UniProtKB:P13864)
8. [The activity of the murine DNA methyltransferase Dnmt1 is controlled by interaction of the catalytic domain with the N-terminal part of the enzyme leading to an allosteric activation of the enzyme after binding to methylated DNA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13864)
9. [Oncogenic RAS directs silencing of tumor suppressor genes through ordered recruitment of transcriptional repressors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13864)
10. [The PHD finger/bromodomain of NoRC interacts with acetylated histone H4K16 and is sufficient for rDNA silencing](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13864)
11. [Usp7 and Uhrf1 control ubiquitination and stability of the maintenance DNA methyltransferase Dnmt1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13864)
12. [Replication-independent chromatin loading of Dnmt1 during G2 and M phases](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13864)
13. [The SRA protein Np95 mediates epigenetic inheritance by recruiting Dnmt1 to methylated DNA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13864)
14. [Analysis of the SWI/SNF chromatin-remodeling complex during early heart development and BAF250a repression cardiac gene transcription during P19 cell differentiation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13864)
15. [DNMT1 interacts with the developmental transcriptional repressor HESX1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13864)
16. [DNMT1 binds HDAC2 and a new co-repressor, DMAP1, to form a complex at replication foci](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13864)
17. [Kcnq1ot1 noncoding RNA mediates transcriptional gene silencing by interacting with Dnmt1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13864)
18. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13864)
19. [Dynamics of Dnmt1 interaction with the replication machinery and its role in postreplicative maintenance of DNA methylation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13864)
20. [Analysis of mammalian proteins involved in chromatin modification reveals new metaphase centromeric proteins and distinct chromosomal distribution patterns](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13864)
21. [Methylation of tRNAAsp by the DNA methyltransferase homolog Dnmt2](http://www.ebi.ac.uk/QuickGO/annotations?protein=P13864&geneProductId=UniProtKB:P13864)
22. [Windows for sex-specific methylation marked by DNA methyltransferase expression profiles in mouse germ cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=P13864&geneProductId=UniProtKB:P13864)
23. [DNMT1 interacts with the developmental transcriptional repressor HESX1](http://www.ebi.ac.uk/QuickGO/annotations?protein=P13864&geneProductId=UniProtKB:P13864)
24. [Expression of DNA methyltransferase (Dnmt1) in testicular germ cells during development of mouse embryo](http://www.ebi.ac.uk/QuickGO/annotations?protein=P13864&geneProductId=UniProtKB:P13864)
25. [Windows for sex-specific methylation marked by DNA methyltransferase expression profiles in mouse germ cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13864)
26. [Methylation of tRNAAsp by the DNA methyltransferase homolog Dnmt2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13864)
27. [Expression of DNA methyltransferase (Dnmt1) in testicular germ cells during development of mouse embryo](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13864)
28. [Dynamics of Dnmt1 interaction with the replication machinery and its role in postreplicative maintenance of DNA methylation](http://www.ebi.ac.uk/QuickGO/annotations?protein=P13864&geneProductId=UniProtKB:P13864)
29. [DNA methylation is a primary mechanism for silencing postmigratory primordial germ cell genes in both germ cell and somatic cell lineages](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13864)
30. [Dnmt1N/+ reduces the net growth rate and multiplicity of intestinal adenomas in C57BL/6-multiple intestinal neoplasia (Min)/+ mice independently of p53 but demonstrates strong synergy with the modifier of Min 1(AKR) resistance allele](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13864)
31. [Difference in expression of hepatic microRNAs miR-29c, miR-34a, miR-155, and miR-200b is associated with strain-specific susceptibility to dietary nonalcoholic steatohepatitis in mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13864)
32. [Cellular adaptation to anthrax lethal toxin-induced mitochondrial cholesterol enrichment, hyperpolarization, and reactive oxygen species generation through downregulating MLN64 in macrophages](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13864)
33. [Negative regulation of CD8 expression via Cd8 enhancer-mediated recruitment of the zinc finger protein MAZR](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13864)
34. [A developmental window of opportunity for imprinted gene silencing mediated by DNA methylation and the Kcnq1ot1 noncoding RNA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13864)
35. [Targeted mutation of the DNA methyltransferase gene results in embryonic lethality](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P13864)
36. ensembl Release 106