# DNA ligase 3

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21117954](https://www.wikidata.org/wiki/Q21117954)  
**Source**: https://4ort.xyz/entity/dna-ligase-3


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P49916)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49916)
5. [Defective DNA single-strand break repair in spinocerebellar ataxia with axonal neuropathy-1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49916)
6. [Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49916)
7. [Promyelocytic leukemia protein interacts with the apoptosis-associated speck-like protein to limit inflammasome activation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49916)
8. [DNA ligase IV is essential for V(D)J recombination and DNA double-strand break repair in human precursor lymphocytes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49916)
9. [The human DNA ligase III gene encodes nuclear and mitochondrial proteins](http://www.ebi.ac.uk/QuickGO/annotations?protein=P49916&geneProductId=UniProtKB:P49916)
10. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P49916&geneProductId=UniProtKB:P49916)
11. [Mammalian DNA ligase III: molecular cloning, chromosomal localization, and expression in spermatocytes undergoing meiotic recombination](http://www.ebi.ac.uk/QuickGO/annotations?protein=P49916&geneProductId=UniProtKB:P49916)
12. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49916)
13. [Characterization of the XRCC1-DNA ligase III complex in vitro and its absence from mutant hamster cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=P49916&geneProductId=UniProtKB:P49916)
14. [DNA ligase III and DNA ligase IV carry out genetically distinct forms of end joining in human somatic cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=P49916&geneProductId=UniProtKB:P49916)
15. [Crucial role for DNA ligase III in mitochondria but not in Xrcc1-dependent repair](http://www.ebi.ac.uk/QuickGO/annotations?protein=P49916&geneProductId=UniProtKB:P49916)
16. [Involvement of DNA ligase III and ribonuclease H1 in mitochondrial DNA replication in cultured human cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49916)
17. [Distinct kinetics of human DNA ligases I, IIIalpha, IIIbeta, and IV reveal direct DNA sensing ability and differential physiological functions in DNA repair](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49916)
18. [Overexpression of DNA ligase III in mitochondria protects cells against oxidative stress and improves mitochondrial DNA base excision repair](http://www.ebi.ac.uk/QuickGO/annotations?protein=P49916&geneProductId=UniProtKB:P49916)
19. [Distinct kinetics of human DNA ligases I, IIIalpha, IIIbeta, and IV reveal direct DNA sensing ability and differential physiological functions in DNA repair](http://www.ebi.ac.uk/QuickGO/annotations?protein=P49916&geneProductId=UniProtKB:P49916)
20. Ensembl Release 99