# DNA ligase 1

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21117820](https://www.wikidata.org/wiki/Q21117820)  
**Source**: https://4ort.xyz/entity/dna-ligase-1-q21117820


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P18858)
3. Q20641742
4. [DNA ligase I is required for fetal liver erythropoiesis but is not essential for mammalian cell viability](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18858)
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18858)
6. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18858)
7. [The human checkpoint sensor and alternative DNA clamp Rad9–Rad1–Hus1 modulates the activity of DNA ligase I, a component of the long-patch base excision repair machinery](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18858)
8. [DNA Ligase IV Is Essential for V(D)J Recombination and DNA Double-Strand Break Repair in Human Precursor Lymphocytes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18858)
9. [DNA ligase I is required for fetal liver erythropoiesis but is not essential for mammalian cell viability](http://www.ebi.ac.uk/QuickGO/annotations?protein=P18858&geneProductId=UniProtKB:P18858)
10. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P18858&geneProductId=UniProtKB:P18858)
11. [Distinct kinetics of human DNA ligases I, IIIα, IIIβ, and IV reveal direct DNA sensing ability and differential physiological functions in DNA repair](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18858)
12. Ensembl Release 99