# DNA-damage inducible transcript 3

> mammalian protein found in Mus musculus

**Wikidata**: [Q21497445](https://www.wikidata.org/wiki/Q21497445)  
**Source**: https://4ort.xyz/entity/dna-damage-inducible-transcript-3-q21497445


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P35639)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35639)
5. [CHOP induces death by promoting protein synthesis and oxidation in the stressed endoplasmic reticulum](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35639)
6. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P35639&geneProductId=UniProtKB:P35639)
7. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?protein=P35639&geneProductId=UniProtKB:P35639)
8. [CHOP enhancement of gene transcription by interactions with Jun/Fos AP-1 complex proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35639)
9. [CHOP, a novel developmentally regulated nuclear protein that dimerizes with transcription factors C/EBP and LAP and functions as a dominant-negative inhibitor of gene transcription](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35639)
10. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35639)
11. [Novel interaction between the transcription factor CHOP (GADD153) and the ribosomal protein FTE/S3a modulates erythropoiesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35639)
12. [Stress-Induced C/EBP Homology Protein (CHOP) Represses MyoD Transcription to Delay Myoblast Differentiation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35639)
13. [ER-stress-induced transcriptional regulation increases protein synthesis leading to cell death.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35639)
14. [Cellular adaptation to anthrax lethal toxin-induced mitochondrial cholesterol enrichment, hyperpolarization, and reactive oxygen species generation through downregulating MLN64 in macrophages](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35639)
15. [Activating transcription factor 3 is integral to the eukaryotic initiation factor 2 kinase stress response](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35639)
16. [hsp70-DnaJ chaperone pair prevents nitric oxide- and CHOP-induced apoptosis by inhibiting translocation of Bax to mitochondria](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35639)
17. [Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35639)
18. [CHOP, a novel developmentally regulated nuclear protein that dimerizes with transcription factors C/EBP and LAP and functions as a dominant-negative inhibitor of gene transcription](http://www.ebi.ac.uk/QuickGO/annotations?protein=P35639&geneProductId=UniProtKB:P35639)
19. [C/EBP homologous protein-10 (CHOP-10) limits postnatal neovascularization through control of endothelial nitric oxide synthase gene expression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35639)
20. [Role of ERO1-alpha-mediated stimulation of inositol 1,4,5-triphosphate receptor activity in endoplasmic reticulum stress-induced apoptosis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35639)
21. [RNase L controls terminal adipocyte differentiation, lipids storage and insulin sensitivity via CHOP10 mRNA regulation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35639)
22. [TRB3, a novel ER stress-inducible gene, is induced via ATF4-CHOP pathway and is involved in cell death](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35639)
23. [CHOP/GADD153 is a mediator of apoptotic death in substantia nigra dopamine neurons in an in vivo neurotoxin model of parkinsonism](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35639)
24. [Neuronal apoptosis induced by endoplasmic reticulum stress is regulated by ATF4-CHOP-mediated induction of the Bcl-2 homology 3-only member PUMA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35639)
25. [Neuronal apoptosis induced by endoplasmic reticulum stress is regulated by ATF4-CHOP-mediated induction of the Bcl-2 homology 3-only member PUMA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P35639&geneProductId=UniProtKB:P35639)
26. [CHOP is implicated in programmed cell death in response to impaired function of the endoplasmic reticulum](http://www.ebi.ac.uk/QuickGO/annotations?protein=P35639&geneProductId=UniProtKB:P35639)
27. [Targeted disruption of the Chop gene delays endoplasmic reticulum stress-mediated diabetes](http://www.ebi.ac.uk/QuickGO/annotations?protein=P35639&geneProductId=UniProtKB:P35639)
28. [The C/EBP homologous protein CHOP (GADD153) is an inhibitor of Wnt/TCF signals](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35639)
29. [Targeted disruption of the Chop gene delays endoplasmic reticulum stress-mediated diabetes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35639)
30. [CHOP is implicated in programmed cell death in response to impaired function of the endoplasmic reticulum](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35639)
31. [Activation of Toll-like receptor 4 (TLR4) attenuates adaptive thermogenesis via endoplasmic reticulum stress.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35639)
32. ensembl Release 106