# Dishevelled segment polarity protein 1

> mammalian protein found in Mus musculus

**Wikidata**: [Q21981314](https://www.wikidata.org/wiki/Q21981314)  
**Source**: https://4ort.xyz/entity/dishevelled-segment-polarity-protein-1


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P51141)
3. Q20641742
4. [Nuclear Factor of Activated T Cells (NFAT) Proteins Repress Canonical Wnt Signaling via Its Interaction with Dishevelled (Dvl) Protein and Participate in Regulating Neural Progenitor Cell Proliferation and Differentiation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51141)
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51141)
6. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51141)
7. [Cytosolic TMEM88 Promotes Invasion and Metastasis in Lung Cancer Cells by Binding DVLS](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51141)
8. [Mammalian Ryk Is a Wnt Coreceptor Required for Stimulation of Neurite Outgrowth](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51141)
9. [Independent Mutations in Mouse Vangl2 That Cause Neural Tube Defects in Looptail Mice Impair Interaction with Members of the Dishevelled Family](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51141)
10. [Inhibition of the Wnt Signaling Pathway by Idax, a Novel Dvl-Binding Protein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51141)
11. [Identification of neuroglobin-interacting proteins using yeast two-hybrid screening](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51141)
12. [Prickle promotes neurite outgrowth via the Dishevelled dependent pathway in C1300 cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51141)
13. [Regulation of AChR Clustering by Dishevelled Interacting with MuSK and PAK1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51141)
14. [A β-Catenin-Independent Dorsalization Pathway Activated by Axin/JNK Signaling and Antagonized by Aida](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51141)
15. [Identification of Transmembrane Protein 88 (TMEM88) as a Dishevelled-binding Protein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51141)
16. [Dual functions of DP1 promote biphasic Wnt‐on and Wnt‐off states during anteroposterior neural patterning](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51141)
17. [Sulindac Inhibits Canonical Wnt Signaling by Blocking the PDZ Domain of the Protein Dishevelled](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51141)
18. [All Dact (Dapper/Frodo) scaffold proteins dimerize and exhibit conserved interactions with Vangl, Dvl, and serine/threonine kinases](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51141)
19. [Direct Binding of the PDZ Domain of Dishevelled to a Conserved Internal Sequence in the C-Terminal Region of Frizzled](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51141)
20. [LRRK2 functions as a Wnt signaling scaffold, bridging cytosolic proteins and membrane-localized LRP6](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51141)
21. [WNT-mediated relocalization of dishevelled proteins](http://www.ebi.ac.uk/QuickGO/annotations?protein=P51141&geneProductId=UniProtKB:P51141)
22. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P51141&geneProductId=UniProtKB:P51141)
23. [Signaling across the synapse: a role for Wnt and Dishevelled in presynaptic assembly and neurotransmitter release](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51141)
24. [Dishevelled proteins regulate cell adhesion in mouse blastocyst and serve to monitor changes in Wnt signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51141)
25. [Frizzled-9 Is Activated by Wnt-2 and Functions in Wnt/β-Catenin Signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51141)
26. [Wnt signaling through Dishevelled, Rac and JNK regulates dendritic development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51141)
27. [A divergent canonical WNT-signaling pathway regulates microtubule dynamics](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51141)
28. [Wnt7a signaling promotes dendritic spine growth and synaptic strength through Ca 2+ /Calmodulin-dependent protein kinase II](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51141)
29. [Wnt signalling tunes neurotransmitter release by directly targeting Synaptotagmin-1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51141)
30. [Overexpression of the mouse dishevelled‐1 protein inhibits GSK‐3β‐mediated phosphorylation of tau in transfected mammalian cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51141)
31. [Antagonistic Functions of Dishevelleds Regulate Frizzled3 Endocytosis via Filopodia Tips in Wnt-Mediated Growth Cone Guidance](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51141)
32. [Second Cysteine-rich Domain of Dickkopf-2 Activates Canonical Wnt Signaling Pathway via LRP-6 Independently of Dishevelled](http://www.ebi.ac.uk/QuickGO/annotations?protein=P51141&geneProductId=UniProtKB:P51141)
33. [Dishevelled genes mediate a conserved mammalian PCP pathway to regulate convergent extension during neurulation](http://www.ebi.ac.uk/QuickGO/annotations?protein=P51141&geneProductId=UniProtKB:P51141)
34. [Wnt Regulates Axon Behavior through Changes in Microtubule Growth Directionality: A New Role for Adenomatous Polyposis Coli](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51141)
35. [Regulation of polarized extension and planar cell polarity in the cochlea by the vertebrate PCP pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51141)
36. [Casein Kinase Iε Modulates the Signaling Specificities of Dishevelled](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51141)
37. [Molecular study of mouse peri‐implantation development using the in vitro culture of aggregated inner cell mass](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51141)
38. [Dishevelled promotes neurite outgrowth in neuronal differentiating neuroblastoma 2A cells, via a DIX-domain dependent pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51141)
39. [Differential mediation of the Wnt canonical pathway by mammalian Dishevelleds-1, -2, and -3](http://www.ebi.ac.uk/QuickGO/annotations?protein=P51141&geneProductId=UniProtKB:P51141)
40. [Murine Dishevelled 3 Functions in Redundant Pathways with Dishevelled 1 and 2 in Normal Cardiac Outflow Tract, Cochlea, and Neural Tube Development](http://www.ebi.ac.uk/QuickGO/annotations?protein=P51141&geneProductId=UniProtKB:P51141)
41. [Casein Kinase Iε Modulates the Signaling Specificities of Dishevelled](http://www.ebi.ac.uk/QuickGO/annotations?protein=P51141&geneProductId=UniProtKB:P51141)
42. [Characterization of Mouse Dishevelled (Dvl) Proteins in Wnt/Wingless Signaling Pathway](http://www.ebi.ac.uk/QuickGO/annotations?protein=P51141&geneProductId=UniProtKB:P51141)
43. [The vacuolar-ATPase inhibitor bafilomycin and mutant VPS35 inhibit canonical Wnt signaling](http://www.ebi.ac.uk/QuickGO/annotations?protein=P51141&geneProductId=UniProtKB:P51141)
44. [Molecular study of mouse peri‐implantation development using the in vitro culture of aggregated inner cell mass](http://www.ebi.ac.uk/QuickGO/annotations?protein=P51141&geneProductId=UniProtKB:P51141)
45. [Expanded characterization of the social interaction abnormalities in mice lacking Dvl1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51141)
46. [Social Interaction and Sensorimotor Gating Abnormalities in Mice Lacking Dvl1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51141)
47. [Wnt signaling promotes AChR aggregation at the neuromuscular synapse in collaboration with agrin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51141)
48. [Dishevelled genes mediate a conserved mammalian PCP pathway to regulate convergent extension during neurulation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P51141)
49. [Inhibition of the Wnt Signaling Pathway by Idax, a Novel Dvl-Binding Protein](http://www.ebi.ac.uk/QuickGO/annotations?protein=P51141&geneProductId=UniProtKB:P51141)
50. [Frat2 mediates the oncogenic activation of Rac by MLL fusions](http://www.ebi.ac.uk/QuickGO/annotations?protein=P51141&geneProductId=UniProtKB:P51141)