# Discs large MAGUK scaffold protein 4

> mammalian protein found in Mus musculus

**Wikidata**: [Q21498713](https://www.wikidata.org/wiki/Q21498713)  
**Source**: https://4ort.xyz/entity/discs-large-maguk-scaffold-protein-4-q21498713


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q62108)
3. Q20641742
4. [Identification of PSD-95 as a regulator of dopamine-mediated synaptic and behavioral plasticity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62108)
5. [Binding of neuroligins to PSD-95](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62108)
6. [DGKι regulates presynaptic release during mGluR-dependent LTD](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62108)
7. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62108)
8. [Neto1 is a novel CUB-domain NMDA receptor-interacting protein required for synaptic plasticity and learning](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62108)
9. [Shisa6 traps AMPA receptors at postsynaptic sites and prevents their desensitization during synaptic activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62108)
10. [The AMPA receptor-associated protein Shisa7 regulates hippocampal synaptic function and contextual memory](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62108)
11. [TMEM16B, a novel protein with calcium-dependent chloride channel activity, associates with a presynaptic protein complex in photoreceptor terminals](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62108)
12. [The association of GPR85 with PSD-95-neuroligin complex and autism spectrum disorder: a molecular analysis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62108)
13. [Brain-specific angiogenesis inhibitor-1 signaling, regulation, and enrichment in the postsynaptic density](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62108)
14. [Cyclin-dependent kinase 5 governs learning and synaptic plasticity via control of NMDAR degradation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62108)
15. [The cytoplasmic domain of NrCAM binds to PDZ domains of synapse-associated proteins SAP90/PSD95 and SAP97](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62108)
16. [NGL family PSD-95-interacting adhesion molecules regulate excitatory synapse formation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62108)
17. [Semaphorin 4B interacts with the post-synaptic density protein PSD-95/SAP90 and is recruited to synapses through a C-terminal PDZ-binding motif](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62108)
18. [Sortilin-related receptor SORCS3 is a postsynaptic modulator of synaptic depression and fear extinction](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62108)
19. [Direct interaction of myosin regulatory light chain with the NMDA receptor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62108)
20. [Comparative analysis of structure, expression and PSD95-binding capacity of Lrfn, a novel family of neuronal transmembrane proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62108)
21. [Semaphorin4F interacts with the synapse-associated protein SAP90/PSD-95](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62108)
22. [ASIC2 subunits target acid-sensing ion channels to the synapse via an association with PSD-95](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62108)
23. [Normal development and fertility of knockout mice lacking the tumor suppressor gene LRP1b suggest functional compensation by LRP1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62108)
24. [Molecular constituents of neuronal AMPA receptors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62108)
25. [Microtubule-associated protein 1A is a modifier of tubby hearing (moth1).](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62108)
26. [CIPP, a Novel Multivalent PDZ Domain Protein, Selectively Interacts with Kir4.0 Family Members, NMDA Receptor Subunits, Neurexins, and Neuroligins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62108)
27. [C-terminal interactors of the AMPA receptor auxiliary subunit Shisa9](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62108)
28. [Direct interaction of Frizzled-1, -2, -4, and -7 with PDZ domains of PSD-95](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62108)
29. [Proteomics analysis of immuno-precipitated synaptic protein complexes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62108)
30. [CIN85 regulates dopamine receptor endocytosis and governs behaviour in mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62108)
31. [DAPK1 interaction with NMDA receptor NR2B subunits mediates brain damage in stroke](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62108)
32. [Corticotropin-Releasing Hormone Receptor Type 1 (CRHR1) Clustering with MAGUKs Is Mediated via Its C-Terminal PDZ Binding Motif](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62108)
33. [Molecular characterization and comparison of the components and multiprotein complexes in the postsynaptic proteome](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62108)
34. [CaMKII binding to GluN2B is critical during memory consolidation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62108)
35. [Multiple autism-linked genes mediate synapse elimination via proteasomal degradation of a synaptic scaffold PSD-95](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62108)
36. [NR2B tyrosine phosphorylation modulates fear learning as well as amygdaloid synaptic plasticity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62108)
37. [Impairment of TrkB-PSD-95 Signaling in Angelman Syndrome](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62108)
38. [Progressive accumulation of amyloid-beta oligomers in Alzheimer's disease and in amyloid precursor protein transgenic mice is accompanied by selective alterations in synaptic scaffold proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62108)
39. [Impaired maturation of dendritic spines without disorganization of cortical cell layers in mice lacking NRG1/ErbB signaling in the central nervous system](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62108)
40. [Proteomic analysis of NMDA receptor-adhesion protein signaling complexes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62108)
41. [Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62108)
42. [Interactions of the low density lipoprotein receptor gene family with cytosolic adaptor and scaffold proteins suggest diverse biological functions in cellular communication and signal transduction](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62108)
43. [Targeted tandem affinity purification of PSD-95 recovers core postsynaptic complexes and schizophrenia susceptibility proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62108)
44. [Apolipoprotein E receptor 2 interactions with the N-methyl-D-aspartate receptor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62108)
45. [A novel family of adhesion-like molecules that interacts with the NMDA receptor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62108)
46. [Interaction of brain somatostatin receptors with the PDZ domains of PSD-95](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62108)
47. [Dual role of the exocyst in AMPA receptor targeting and insertion into the postsynaptic membrane](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62108)
48. [Defects in Synaptic Plasticity, Reduced NMDA-Receptor Transport, and Instability of Postsynaptic Density Proteins in Mice Lacking Microtubule-Associated Protein 1A.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62108)
49. [Direct interaction of GluRdelta2 with Shank scaffold proteins in cerebellar Purkinje cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62108)
50. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62108)