# Discs large MAGUK scaffold protein 1

> mammalian protein found in Mus musculus

**Wikidata**: [Q21982917](https://www.wikidata.org/wiki/Q21982917)  
**Source**: https://4ort.xyz/entity/discs-large-maguk-scaffold-protein-1-q21982917


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q811D0)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q811D0)
5. [DGKι regulates presynaptic release during mGluR-dependent LTD](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q811D0)
6. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q811D0&geneProductId=UniProtKB:Q811D0)
7. [The cytoplasmic domain of NrCAM binds to PDZ domains of synapse-associated proteins SAP90/PSD95 and SAP97](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q811D0)
8. [Synapse-associated protein-97 mediates alpha-secretase ADAM10 trafficking and promotes its activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q811D0)
9. [NGL family PSD-95-interacting adhesion molecules regulate excitatory synapse formation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q811D0)
10. [Dlg1, Sec8, and Mtmr2 regulate membrane homeostasis in Schwann cell myelination](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q811D0)
11. [Scaffold protein Dlgh1 coordinates alternative p38 kinase activation, directing T cell receptor signals toward NFAT but not NF-kappaB transcription factors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q811D0)
12. [Dlgh1 coordinates actin polymerization, synaptic T cell receptor and lipid raft aggregation, and effector function in T cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q811D0)
13. [Mutagenesis of the epithelial polarity gene, discs large 1, perturbs nephrogenesis in the developing mouse kidney](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q811D0)
14. [Dlg1-PTEN interaction regulates myelin thickness to prevent damaging peripheral nerve overmyelination](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q811D0)
15. [Identification of multiple binding partners for the amino-terminal domain of synapse-associated protein 97](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q811D0)
16. [Caveolin-3 and SAP97 form a scaffolding protein complex that regulates the voltage-gated potassium channel Kv1.5](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q811D0)
17. [Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q811D0)
18. [A novel family of adhesion-like molecules that interacts with the NMDA receptor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q811D0)
19. [Targeted tandem affinity purification of PSD-95 recovers core postsynaptic complexes and schizophrenia susceptibility proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q811D0)
20. [Structures of a human papillomavirus (HPV) E6 polypeptide bound to MAGUK proteins: mechanisms of targeting tumor suppressors by a high-risk HPV oncoprotein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q811D0)
21. [Cardiac-specific ablation of synapse-associated protein SAP97 in mice decreases potassium currents but not sodium current](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q811D0)
22. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q811D0)
23. [The role of SAP97 in synaptic glutamate receptor dynamics](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q811D0)
24. [Pals1 is a major regulator of the epithelial-like polarization and the extension of the myelin sheath in peripheral nerves](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q811D0)
25. [Membrane localization of adenomatous polyposis coli protein at cellular protrusions: targeting sequences and regulation by beta-catenin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q811D0)
26. [Localization of Dlg at the mammalian neuromuscular junction](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q811D0&geneProductId=UniProtKB:Q811D0)
27. [Dlg3 trafficking and apical tight junction formation is regulated by nedd4 and nedd4-2 e3 ubiquitin ligases](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q811D0&geneProductId=UniProtKB:Q811D0)
28. [Identification of multiple binding partners for the amino-terminal domain of synapse-associated protein 97](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q811D0&geneProductId=UniProtKB:Q811D0)
29. [Craniofacial dysmorphogenesis including cleft palate in mice with an insertional mutation in the discs large gene](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q811D0&geneProductId=UniProtKB:Q811D0)
30. [Sox9 plays multiple roles in the lung epithelium during branching morphogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q811D0)
31. [Craniofacial dysmorphogenesis including cleft palate in mice with an insertional mutation in the discs large gene](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q811D0)
32. [Dlg3 trafficking and apical tight junction formation is regulated by nedd4 and nedd4-2 e3 ubiquitin ligases](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q811D0)
33. [Localization of Dlg at the mammalian neuromuscular junction](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q811D0)
34. [Abnormal development of urogenital organs in Dlgh1-deficient mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q811D0)
35. [Dlg, Scribble and Lgl in cell polarity, cell proliferation and cancer](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q811D0)
36. [Discs-large homolog 1 regulates smooth muscle orientation in the mouse ureter](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q811D0)
37. [Requirement of PDZ-containing proteins for cell cycle regulation and differentiation in the mouse lens epithelium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q811D0)
38. [DLGH1 is a negative regulator of T-lymphocyte proliferation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q811D0)
39. ensembl Release 106