# Death domain associated protein

> mammalian protein found in Homo sapiens

**Wikidata**: [Q3019283](https://www.wikidata.org/wiki/Q3019283)  
**Source**: https://4ort.xyz/entity/death-domain-associated-protein


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q9UER7)
3. Q20641742
4. [Negative modulation of androgen receptor transcriptional activity by Daxx](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UER7)
5. [EAP1/Daxx interacts with ETS1 and represses transcriptional activation of ETS1 target genes](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UER7&geneProductId=UniProtKB:Q9UER7)
6. [The tumour suppressor RASSF1A promotes MDM2 self-ubiquitination by disrupting the MDM2-DAXX-HAUSP complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UER7)
7. [The death-associated protein DAXX is a novel histone chaperone involved in the replication-independent deposition of H3.3](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UER7)
8. [Daxx and histone deacetylase II associate with chromatin through an interaction with core histones and the chromatin-associated protein Dek](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UER7)
9. [Distinct factors control histone variant H3.3 localization at specific genomic regions](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UER7)
10. [Critical role for Daxx in regulating Mdm2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UER7)
11. [Interaction of DJ-1 with Daxx inhibits apoptosis signal-regulating kinase 1 activity and cell death](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UER7)
12. [SUMO5, a Novel Poly-SUMO Isoform, Regulates PML Nuclear Bodies.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UER7)
13. [DAXX interacts with heat shock factor 1 during stress activation and enhances its transcriptional activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UER7)
14. [Daxx is an H3.3-specific histone chaperone and cooperates with ATRX in replication-independent chromatin assembly at telomeres](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UER7)
15. [ATRX binds to atypical chromatin domains at the 3' exons of zinc finger genes to preserve H3K9me3 enrichment](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UER7)
16. [Inhibition of NF-kappaB acetylation and its transcriptional activity by Daxx](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UER7)
17. [Adenovirus E1B 55-kilodalton oncoprotein binds to Daxx and eliminates enhancement of p53-dependent transcription by Daxx](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UER7)
18. [Release of RASSF1C from the nucleus by Daxx degradation links DNA damage and SAPK/JNK activation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UER7)
19. [Activation of apoptosis signal-regulating kinase 1 (ASK1) by the adapter protein Daxx](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UER7)
20. [A human MAP kinase interactome](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UER7)
21. [A proteome-scale map of the human interactome network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UER7)
22. [Inhibition of Daxx-mediated apoptosis by heat shock protein 27](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UER7)
23. [The ATRX syndrome protein forms a chromatin-remodeling complex with Daxx and localizes in promyelocytic leukemia nuclear bodies](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UER7)
24. [Ubc9 acetylation modulates distinct SUMO target modification and hypoxia response](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UER7)
25. [DAXX is a new AIRE-interacting protein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UER7)
26. [ATRX dysfunction induces replication defects in primary mouse cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UER7)
27. [Sequestration and inhibition of Daxx-mediated transcriptional repression by PML](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UER7)
28. [Physical and functional interactions between Daxx and STAT3](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UER7)
29. [Negative regulation of p53 functions by Daxx and the involvement of MDM2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UER7)
30. [Daxx, a Novel Fas-Binding Protein That Activates JNK and Apoptosis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UER7)
31. [FTH1 binds to Daxx and inhibits Daxx-mediated cell apoptosis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UER7)
32. [A Comprehensive Resource of Interacting Protein Regions for Refining Human Transcription Factor Networks](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UER7)
33. [Physical and functional interactions between Daxx and TSG101](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UER7)
34. [Interpreting cancer genomes using systematic host network perturbations by tumour virus proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UER7)
35. [p14ARF interacts with DAXX: effects on HDM2 and p53](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UER7)
36. [A Cul4 E3 ubiquitin ligase regulates histone hand-off during nucleosome assembly.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UER7)
37. [Essential role of the 58-kDa microspherule protein in the modulation of Daxx-dependent transcriptional repression as revealed by nucleolar sequestration](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UER7)
38. [The interaction of Pax5 (BSAP) with Daxx can result in transcriptional activation in B cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UER7)
39. [Apoptosis signal-regulating kinase 1 controls the proapoptotic function of death-associated protein (Daxx) in the cytoplasm](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UER7)
40. [TGF-beta-induced apoptosis is mediated by the adapter protein Daxx that facilitates JNK activation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UER7)
41. [Interaction of Daxx, a Fas binding protein, with sentrin and Ubc9](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UER7)
42. [Daxx Silencing Sensitizes Cells to Multiple Apoptotic Pathways](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UER7)
43. [Physiological and functional interactions between Tcf4 and Daxx in colon cancer cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UER7)
44. [Using an in Situ Proximity Ligation Assay to Systematically Profile Endogenous Protein–Protein Interactions in a Pathway Network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UER7)
45. [A Y2H-seq approach defines the human protein methyltransferase interactome](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UER7)
46. [A human interactome in three quantitative dimensions organized by stoichiometries and abundances](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UER7)
47. [EAP1/Daxx interacts with ETS1 and represses transcriptional activation of ETS1 target genes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UER7)
48. [Daxx is a key downstream component of receptor interacting protein kinase 3 mediating retinal ischemic cell death](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UER7)
49. [EBV Tegument Protein BNRF1 Disrupts DAXX-ATRX to Activate Viral Early Gene Transcription](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UER7)
50. [Toward an understanding of the protein interaction network of the human liver](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UER7)