# DEAD-box helicase 5

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21170314](https://www.wikidata.org/wiki/Q21170314)  
**Source**: https://4ort.xyz/entity/dead-box-helicase-5


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P17844)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17844)
5. [Transcription-dependent nucleolar cap localization and possible nuclear function of DExH RNA helicase RHAU.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17844)
6. [The RNA helicase Ddx5/p68 binds to hUpf3 and enhances NMD of Ddx17/p72 and Smg5 mRNA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17844)
7. [RNA helicase p68 (DDX5) regulates tau exon 10 splicing by modulating a stem-loop structure at the 5' splice site](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17844)
8. [Proteomic and functional analysis of Argonaute-containing mRNA-protein complexes in human cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17844)
9. [RNA helicases DDX5 and DDX17 dynamically orchestrate transcription, miRNA, and splicing programs in cell differentiation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17844)
10. [p68 (Ddx5) interacts with Runx2 and regulates osteoblast differentiation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17844)
11. [Dual role of the ddx5/ddx17 RNA helicases in the control of the pro-migratory NFAT5 transcription factor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17844)
12. [The nuclear DEAD box RNA helicase p68 interacts with the nucleolar protein fibrillarin and colocalizes specifically in nascent nucleoli during telophase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17844)
13. [Dynamic protein-protein interaction wiring of the human spliceosome](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17844)
14. [A physical interaction network of dengue virus and human proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17844)
15. [The p68 and p72 DEAD box RNA helicases interact with HDAC1 and repress transcription in a promoter-specific manner](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17844)
16. [The RNA helicase DDX5/p68 is a key factor promoting c-fos expression at different levels from transcription to mRNA export](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17844)
17. [Synergism between p68 RNA helicase and the transcriptional coactivators CBP and p300](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17844)
18. [Generation and comprehensive analysis of an influenza virus polymerase cellular interaction network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17844)
19. [Modulation of microRNA processing by p53](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17844)
20. [Mammalian splicing factor SF1 interacts with SURP domains of U2 snRNP-associated proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17844)
21. [Acetylation of p53 stimulates miRNA processing and determines cell survival following genotoxic stress](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17844)
22. [The RNA helicases p68/p72 and the noncoding RNA SRA are coregulators of MyoD and skeletal muscle differentiation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17844)
23. [SMAD proteins control DROSHA-mediated microRNA maturation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17844)
24. [Identification of intracellular proteins associated with the EBV-encoded nuclear antigen 5 using an efficient TAP procedure and FT-ICR mass spectrometry](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17844)
25. [The DEAD box protein p68: a novel transcriptional coactivator of the p53 tumour suppressor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17844)
26. [Phosphorylated p68 RNA helicase activates snail1 transcription by promoting HDAC1 dissociation from the snail1 promoter](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17844)
27. [Hippo signaling regulates microprocessor and links cell-density-dependent miRNA biogenesis to cancer](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17844)
28. [The variable N-terminal region of DDX5 contains structural elements and auto-inhibits its interaction with NS5B of hepatitis C virus](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17844)
29. [Histone deacetylase 1 enhances microRNA processing via deacetylation of DGCR8](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17844)
30. [The RNA helicase p68 modulates expression and function of the Δ133 isoform(s) of p53, and is inversely associated with Δ133p53 expression in breast cancer](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17844)
31. [Cellular RNA helicase p68 relocalization and interaction with the hepatitis C virus (HCV) NS5B protein and the potential role of p68 in HCV RNA replication](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17844)
32. [DDX5 Facilitates HIV-1 Replication as a Cellular Co-Factor of Rev](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17844)
33. [Host factors that interact with the pestivirus N-terminal protease, Npro, are components of the ribonucleoprotein complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17844)
34. [Proteomic profiling of cellular proteins interacting with the hepatitis C virus core protein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17844)
35. [The RNA helicase p68 is a novel androgen receptor coactivator involved in splicing and is overexpressed in prostate cancer](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17844)
36. [p68 RNA helicase: identification of a nucleolar form and cloning of related genes containing a conserved intron in yeasts](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17844)
37. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P17844&geneProductId=UniProtKB:P17844)
38. [Insights into RNA biology from an atlas of mammalian mRNA-binding proteins](http://www.ebi.ac.uk/QuickGO/annotations?protein=P17844&geneProductId=UniProtKB:P17844)
39. [The mRNA-Bound Proteome and Its Global Occupancy Profile on Protein-Coding Transcripts](http://www.ebi.ac.uk/QuickGO/annotations?protein=P17844&geneProductId=UniProtKB:P17844)
40. [The mRNA-Bound Proteome and Its Global Occupancy Profile on Protein-Coding Transcripts](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17844)
41. [Insights into RNA biology from an atlas of mammalian mRNA-binding proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17844)
42. [Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17844)
43. [Defining the membrane proteome of NK cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=P17844&geneProductId=UniProtKB:P17844)
44. [Large-scale proteomics and phosphoproteomics of urinary exosomes](http://www.ebi.ac.uk/QuickGO/annotations?protein=P17844&geneProductId=UniProtKB:P17844)
45. [Nuclear protein with sequence homology to translation initiation factor eIF-4A](http://www.ebi.ac.uk/QuickGO/annotations?protein=P17844&geneProductId=UniProtKB:P17844)
46. [RNA helicases DDX5 and DDX17 dynamically orchestrate transcription, miRNA, and splicing programs in cell differentiation](http://www.ebi.ac.uk/QuickGO/annotations?protein=P17844&geneProductId=UniProtKB:P17844)
47. [Dynamic proteomics in individual human cells uncovers widespread cell-cycle dependence of nuclear proteins](http://www.ebi.ac.uk/QuickGO/annotations?protein=P17844&geneProductId=UniProtKB:P17844)
48. [SILAC-based proteomics of human primary endothelial cell morphogenesis unveils tumor angiogenic markers](http://www.ebi.ac.uk/QuickGO/annotations?protein=P17844&geneProductId=UniProtKB:P17844)
49. [SMAD proteins control DROSHA-mediated microRNA maturation](http://www.ebi.ac.uk/QuickGO/annotations?protein=P17844&geneProductId=UniProtKB:P17844)
50. [Nuclear protein with sequence homology to translation initiation factor eIF-4A](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17844)