# DEAD-box helicase 3 X-linked

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21105627](https://www.wikidata.org/wiki/Q21105627)  
**Source**: https://4ort.xyz/entity/dead-box-helicase-3-x-linked


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/O00571)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00571)
5. [A motif unique to the human DEAD-box protein DDX3 is important for nucleic acid binding, ATP hydrolysis, RNA/DNA unwinding and HIV-1 replication](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00571)
6. [Hepatitis C virus core protein interacts with cellular putative RNA helicase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00571)
7. [The DEAD-box RNA helicase DDX3 associates with export messenger ribonucleoproteins as well as tip-associated protein and participates in translational control](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00571)
8. [The DEAD-box helicase DDX3 supports the assembly of functional 80S ribosomes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00571)
9. [DEAD-box protein DDX3 associates with eIF4F to promote translation of selected mRNAs](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00571)
10. [DDX3, a DEAD box RNA helicase with tumor growth-suppressive property and transcriptional regulation activity of the p21waf1/cip1 promoter, is a candidate tumor suppressor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00571)
11. [RNA helicase DDX3 is a regulatory subunit of casein kinase 1 in Wnt-β-catenin signaling.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00571)
12. [The DHX33 RNA Helicase Promotes mRNA Translation Initiation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00571)
13. [Hepatitis B virus polymerase blocks pattern recognition receptor signaling via interaction with DDX3: implications for immune evasion](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00571)
14. [Viral targeting of DEAD box protein 3 reveals its role in TBK1/IKKepsilon-mediated IRF activation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00571)
15. [DDX3 DEAD-box RNA helicase is required for hepatitis C virus RNA replication](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00571)
16. [Hepatitis C virus core-derived peptides inhibit genotype 1b viral genome replication via interaction with DDX3X](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00571)
17. [Structural basis for targeting of human RNA helicase DDX3 by poxvirus protein K7](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00571)
18. [Hepatitis C virus core protein interacts with a human DEAD box protein DDX3](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00571)
19. [Hepatitis C virus infection protein network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00571)
20. [Human DDX3 functions in translation and interacts with the translation initiation factor eIF3](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00571)
21. [DEAD-box RNA helicase Belle/DDX3 and the RNA interference pathway promote mitotic chromosome segregation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00571)
22. [Elucidating novel hepatitis C virus-host interactions using combined mass spectrometry and functional genomics approaches](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00571)
23. [Viral immune modulators perturb the human molecular network by common and unique strategies](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00571)
24. [Human DDX3 interacts with the HIV-1 Tat protein to facilitate viral mRNA translation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00571)
25. [Critical roles of RNA helicase DDX3 and its interactions with eIF4E/PABP1 in stress granule assembly and stress response](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00571)
26. [Hepatitis C virus core protein binds to a DEAD box RNA helicase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00571)
27. [The TRPM7 chanzyme is cleaved to release a chromatin-modifying kinase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00571)
28. [Modulation of the type I interferon pathways by culture‐adaptive hepatitis C virus core mutants](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00571)
29. [DEAD/H BOX 3 (DDX3) helicase binds the RIG-I adaptor IPS-1 to up-regulate IFN-beta-inducing potential](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00571)
30. [Candidate tumor suppressor DDX3 RNA helicase specifically represses cap-dependent translation by acting as an eIF4E inhibitory protein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00571)
31. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=O00571&geneProductId=UniProtKB:O00571)
32. [A motif unique to the human DEAD-box protein DDX3 is important for nucleic acid binding, ATP hydrolysis, RNA/DNA unwinding and HIV-1 replication](http://www.ebi.ac.uk/QuickGO/annotations?protein=O00571&geneProductId=UniProtKB:O00571)
33. [Insights into RNA biology from an atlas of mammalian mRNA-binding proteins](http://www.ebi.ac.uk/QuickGO/annotations?protein=O00571&geneProductId=UniProtKB:O00571)
34. [The mRNA-Bound Proteome and Its Global Occupancy Profile on Protein-Coding Transcripts](http://www.ebi.ac.uk/QuickGO/annotations?protein=O00571&geneProductId=UniProtKB:O00571)
35. [RNA Remodeling Activity of DEAD Box Proteins Tuned by Protein Concentration, RNA Length, and ATP](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00571)
36. [E-cadherin interactome complexity and robustness resolved by quantitative proteomics](http://www.ebi.ac.uk/QuickGO/annotations?protein=O00571&geneProductId=UniProtKB:O00571)
37. [The mRNA-Bound Proteome and Its Global Occupancy Profile on Protein-Coding Transcripts](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00571)
38. [Insights into RNA biology from an atlas of mammalian mRNA-binding proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00571)
39. [E-cadherin interactome complexity and robustness resolved by quantitative proteomics](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00571)
40. [Host factors that interact with the pestivirus N-terminal protease, Npro, are components of the ribonucleoprotein complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00571)
41. [Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT)](http://www.ebi.ac.uk/QuickGO/annotations?protein=O00571&geneProductId=UniProtKB:O00571)
42. [Large-scale proteomics and phosphoproteomics of urinary exosomes](http://www.ebi.ac.uk/QuickGO/annotations?protein=O00571&geneProductId=UniProtKB:O00571)
43. [MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis](http://www.ebi.ac.uk/QuickGO/annotations?protein=O00571&geneProductId=UniProtKB:O00571)
44. [Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT)](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00571)
45. [MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00571)
46. [Large-scale proteomics and phosphoproteomics of urinary exosomes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00571)
47. [Identification of an antiapoptotic protein complex at death receptors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00571)
48. [Mutations in DDX3X Are a Common Cause of Unexplained Intellectual Disability with Gender-Specific Effects on Wnt Signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00571)
49. [DDX3 regulates cell growth through translational control of cyclin E1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00571)
50. [DDX3, a DEAD box RNA helicase, is deregulated in hepatitis virus-associated hepatocellular carcinoma and is involved in cell growth control](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00571)