# De novo clustering methods outperform reference-based methods for assigning 16S rRNA gene sequences to operational taxonomic units

> Research article (PeerJ, 2015) · cited 300× · AI/ML

**Wikidata**: [openalex:W1846216853](https://www.wikidata.org/wiki/openalex:W1846216853)  
**Source**: https://4ort.xyz/entity/de-novo-clustering-methods-outperform-reference-based-methods-for-assigning-16s-rrna-gene-sequences-to-operational-taxon