# DDB1 and CUL4 associated factor 1

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21112163](https://www.wikidata.org/wiki/Q21112163)  
**Source**: https://4ort.xyz/entity/ddb1-and-cul4-associated-factor-1


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q9Y4B6)
3. [Swiss-Prot](http://www.uniprot.org/uniprot/Q9Y4B6.txt?version=121)
4. Q20641742
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y4B6)
6. [VprBP has intrinsic kinase activity targeting histone H2A and represses gene transcription](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y4B6&geneProductId=UniProtKB:Q9Y4B6)
7. [Merlin/NF2 suppresses tumorigenesis by inhibiting the E3 ubiquitin ligase CRL4(DCAF1) in the nucleus](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y4B6)
8. [A family of diverse Cul4-Ddb1-interacting proteins includes Cdt2, which is required for S phase destruction of the replication factor Cdt1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y4B6)
9. [Global landscape of HIV-human protein complexes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y4B6)
10. [Merlin/NF2 loss-driven tumorigenesis linked to CRL4(DCAF1)-mediated inhibition of the hippo pathway kinases Lats1 and 2 in the nucleus](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y4B6)
11. [Structural basis of lentiviral subversion of a cellular protein degradation pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y4B6)
12. [The human immunodeficiency virus type 2 Vpx protein usurps the CUL4A-DDB1 DCAF1 ubiquitin ligase to overcome a postentry block in macrophage infection](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y4B6)
13. [Premature activation of the SLX4 complex by Vpr promotes G2/M arrest and escape from innate immune sensing](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y4B6)
14. [VprBP binds full-length RAG1 and is required for B-cell development and V(D)J recombination fidelity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y4B6)
15. [The Hippo kinases LATS1 and 2 control human breast cell fate via crosstalk with ERα](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y4B6&geneProductId=UniProtKB:Q9Y4B6)
16. [The Hippo kinases LATS1 and 2 control human breast cell fate via crosstalk with ERα](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y4B6)
17. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y4B6)
18. [VprBP has intrinsic kinase activity targeting histone H2A and represses gene transcription](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y4B6)
19. [Characterization of the human COP9 signalosome complex using affinity purification and mass spectrometry](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y4B6)
20. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y4B6&geneProductId=UniProtKB:Q9Y4B6)
21. [Merlin/NF2 suppresses tumorigenesis by inhibiting the E3 ubiquitin ligase CRL4(DCAF1) in the nucleus](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y4B6&geneProductId=UniProtKB:Q9Y4B6)
22. [A family of diverse Cul4-Ddb1-interacting proteins includes Cdt2, which is required for S phase destruction of the replication factor Cdt1](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Y4B6&geneProductId=UniProtKB:Q9Y4B6)
23. [Involvement of Lgl and Mahjong/VprBP in cell competition](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y4B6)
24. Ensembl Release 99