# Cytohesin 2

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21116206](https://www.wikidata.org/wiki/Q21116206)  
**Source**: https://4ort.xyz/entity/cytohesin-2-q21116206


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q99418)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99418)
5. [CNK3 and IPCEF1 produce a single protein that is required for HGF dependent Arf6 activation and migration](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99418)
6. [C1orf106 is a colitis risk gene that regulates stability of epithelial adherens junctions.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99418)
7. [The Arl4 family of small G proteins can recruit the cytohesin Arf6 exchange factors to the plasma membrane](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99418)
8. [Heterotrimeric G protein-independent signaling of a G protein-coupled receptor. Direct binding of ARNO/cytohesin-2 to the carboxyl terminus of the A2A adenosine receptor is necessary for sustained activation of the ERK/MAP kinase pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99418)
9. [Structural snapshots of the mechanism and inhibition of a guanine nucleotide exchange factor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99418)
10. [Towards a proteome-scale map of the human protein–protein interaction network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99418)
11. [A proteome-scale map of the human interactome network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99418)
12. [Structure-based discovery of an inhibitor of Arf activation by Sec7 domains through targeting of protein-protein complexes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99418)
13. [V-ATPase interacts with ARNO and Arf6 in early endosomes and regulates the protein degradative pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99418)
14. [Brefeldin A acts to stabilize an abortive ARF-GDP-Sec7 domain protein complex: involvement of specific residues of the Sec7 domain](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99418)
15. [Interleukin receptor activates a MYD88-ARNO-ARF6 cascade to disrupt vascular stability.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99418)
16. [ARNO Is a Guanine Nucleotide Exchange Factor for ADP-ribosylation Factor 6](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q99418)
17. Ensembl Release 99