cytochrome P450 family 51 subfamily A member 1
type: Thing
description: mammalian protein found in Homo sapiens
additional property: PropertyValue
  property ID: P31
  value: protein
additional property: PropertyValue
  property ID: P129
  value: azalanstat
additional property: PropertyValue
  property ID: P352
  value: Toivo Nykänen
additional property: PropertyValue
  property ID: P361
  value: cytochrome P450 superfamily
additional property: PropertyValue
  property ID: P361
  value: cytochrome P450, E-class, group IV
additional property: PropertyValue
  property ID: P361
  value: cytochrome P450, conserved site, protein family
additional property: PropertyValue
  property ID: P527
  value: cytochrome P450, conserved site
additional property: PropertyValue
  property ID: P637
  value: NP_000777
additional property: PropertyValue
  property ID: P637
  value: NP_001139624
additional property: PropertyValue
  property ID: P638
  value: 3JUS
additional property: PropertyValue
  property ID: P638
  value: 3JUV
additional property: PropertyValue
  property ID: P638
  value: 3LD6
additional property: PropertyValue
  property ID: P680
  value: iron ion binding
additional property: PropertyValue
  property ID: P680
  value: metal ion binding
additional property: PropertyValue
  property ID: P680
  value: monooxygenase activity
additional property: PropertyValue
  property ID: P681
  value: integral component of membrane
additional property: PropertyValue
  property ID: P681
  value: organelle membrane
additional property: PropertyValue
  property ID: P681
  value: endoplasmic reticulum membrane
additional property: PropertyValue
  property ID: P682
  value: steroid metabolic process
additional property: PropertyValue
  property ID: P682
  value: sterol biosynthetic process
additional property: PropertyValue
  property ID: P682
  value: lipid metabolism
additional property: PropertyValue
  property ID: P702
  value: CYP51A1
additional property: PropertyValue
  property ID: P703
  value: Homo sapiens
additional property: PropertyValue
  property ID: P705
  value: ENSP00000406757
additional property: PropertyValue
  property ID: P705
  value: ENSP00000003100
additional property: PropertyValue
  property ID: P705
  value: ENSP00000394268
confidence:
  popularity graph score:
    score: 0.002
    score pct: 0
    tier: established
    components:
      sitelinks: 0
      sitelinks norm: 0.0
      unique citations: 12
      unique citations norm: 0.005
      monthly pageviews: 0
      monthly pageviews norm: 0.0
  sitelinks: 0
  unique citations: 12
  monthly pageviews: 0
  yearly pageviews: 0
  tier: established
claims:
  P31:
    value: Q8054
    source count: 1
    confidence: 0.2
    value label: protein
  P129:
    value: Q4832127
    source count: 1
    confidence: 0.2
    value label: azalanstat
  P352:
    value: Q16850
    source count: 1
    confidence: 0.2
    value label: Toivo Nykänen
  P361:
    value: Q41797511
    source count: 1
    confidence: 0.2
    value label: cytochrome P450 superfamily
  P361:
    value: Q24720519
    source count: 1
    confidence: 0.2
    value label: cytochrome P450, E-class, group IV
  P361:
    value: Q95352863
    source count: 1
    confidence: 0.2
    value label: cytochrome P450, conserved site, protein family
  P527:
    value: Q24724586
    source count: 1
    confidence: 0.2
    value label: cytochrome P450, conserved site
  P637:
    value: NP_000777
    source count: 1
    confidence: 0.2
  P637:
    value: NP_001139624
    source count: 1
    confidence: 0.2
  P638:
    value: 3JUS
    source count: 1
    confidence: 0.2
  P638:
    value: 3JUV
    source count: 1
    confidence: 0.2
  P638:
    value: 3LD6
    source count: 1
    confidence: 0.2
  P638:
    value: 4UHI
    source count: 1
    confidence: 0.2
  P638:
    value: 4UHL
    source count: 1
    confidence: 0.2
  P680:
    value: Q14358439
    source count: 1
    confidence: 0.2
    value label: iron ion binding
  P680:
    value: Q13667380
    source count: 1
    confidence: 0.2
    value label: metal ion binding
  P680:
    value: Q14358814
    source count: 2
    confidence: 0.4
    value label: monooxygenase activity
  P680:
    value: Q14358516
    source count: 2
    confidence: 0.4
    value label: heme binding
  P680:
    value: Q14358843
    source count: 1
    confidence: 0.2
    value label: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
  P681:
    value: Q14327652
    source count: 1
    confidence: 0.2
    value label: integral component of membrane
  P681:
    value: Q14878067
    source count: 1
    confidence: 0.2
    value label: organelle membrane
  P681:
    value: Q14329032
    source count: 2
    confidence: 0.4
    value label: endoplasmic reticulum membrane

value: Q14349455
source count: 2
confidence: 0.4
value label: membrane

value: Q14349519
source count: 1
confidence: 0.2
value label: intracellular membrane-bounded organelle

value: Q14327702
source count: 1
confidence: 0.2
value label: steroid metabolic process

value: Q14599661
source count: 1
confidence: 0.2
value label: sterol biosynthetic process

value: Q2792936
source count: 1
confidence: 0.2
value label: lipid metabolism

value: Q14599650
source count: 1
confidence: 0.2
value label: cholesterol metabolic process

value: Q21423011
source count: 1
confidence: 0.2
value label: cholesterol biosynthetic process via 24,25-dihydrolanosterol

value: Q17912234
source count: 1
confidence: 0.2
value label: CYP51A1

value: Q15978631
source count: 1
confidence: 0.2
value label: Homo sapiens

value: ENSP00000406757
source count: 1
confidence: 0.2

value: ENSP00000003100
source count: 1
confidence: 0.2

value: ENSP00000394268
source count: 1
confidence: 0.2

source: GOA
stated in qid: Q28018111
retrieved: 2019-04-08

source: Structural basis of human CYP51 inhibition by antifungal azoles
stated in qid: Q24299075
retrieved: 2019-04-08

source: GOA
stated in qid: Q28018111
retrieved: 2017-09-26

source: Structural basis of human CYP51 inhibition by antifungal azoles
stated in qid: Q24299075
retrieved: 2017-09-26

source: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
stated in qid: Q34211397
retrieved: 2019-04-08

source: Defining the membrane proteome of NK cells
stated in qid: Q24323157
retrieved: 2017-09-26

source: Defining the membrane proteome of NK cells
stated in qid: Q24323157
retrieved: 2019-04-08

source: InterPro Release 71.0
stated in qid: Q58943792

source: UniProt
stated in qid: Q905695
retrieved: 2019-11-13

source: IUPHAR/BPS Guide to PHARMACOLOGY
stated in qid: Q17091219
retrieved: 2016-08-17

source: Q20641742
stated in qid: Q20641742
retrieved: 2020-05-30

source: Ensembl Release 99
stated in qid: Q83867711

wikidata id: Q21100886
domain: protein
level: standard
html url: https://4ort.xyz/entity/cytochrome-p450-family-51-subfamily-a-member-1
markdown url: https://4ort.xyz/entity/cytochrome-p450-family-51-subfamily-a-member-1.md
facts url summary: https://4ort.xyz/entity/cytochrome-p450-family-51-subfamily-a-member-1/facts.json
facts url standard: https://4ort.xyz/entity/cytochrome-p450-family-51-subfamily-a-member-1/facts.json
facts url full: https://4ort.xyz/entity/cytochrome-p450-family-51-subfamily-a-member-1/facts.json
data source: Wikidata (CC0 / public domain)
license: https://creativecommons.org/publicdomain/zero/1.0/
api version: v1
served at: 2026-08-13T07:27:02.961917Z
entity updated at: 2026-05-03T18:28:36.114423+00:00Z
entity created at: 2026-05-03T15:12:06.018882+00:00Z