Cytochrome P450, family 27, subfamily a, polypeptide 1
type: Thing
description: mammalian protein found in Rattus norvegicus
additional property: PropertyValue
  property ID: P31
  value: protein
additional property: PropertyValue
  property ID: P352
  value: P17178
additional property: PropertyValue
  property ID: P361
  value: cytochrome P450 superfamily
additional property: PropertyValue
  property ID: P361
  value: cytochrome P450, E-class, group I
additional property: PropertyValue
  property ID: P361
  value: membrane protein
additional property: PropertyValue
  property ID: P527
  value: cytochrome P450, conserved site
additional property: PropertyValue
  property ID: P637
  value: NP_849178
additional property: PropertyValue
  property ID: P637
  value: XP_038939288
additional property: PropertyValue
  property ID: P680
  value: monooxygenase activity
additional property: PropertyValue
  property ID: P680
  value: iron ion binding
additional property: PropertyValue
  property ID: P680
  value: oxidoreductase activity
additional property: PropertyValue
  property ID: P681
  value: mitochondrion
additional property: PropertyValue
  property ID: P681
  value: mitochondrial envelope
additional property: PropertyValue
  property ID: P681
  value: membrane
additional property: PropertyValue
  property ID: P682
  value: steroid catabolic process
additional property: PropertyValue
  property ID: P682
  value: cholesterol metabolic process
additional property: PropertyValue
  property ID: P682
  value: calcitriol biosynthetic process from calciol
additional property: PropertyValue
  property ID: P702
  value: Cyp27a1
additional property: PropertyValue
  property ID: P703
  value: brown rat
additional property: PropertyValue
  property ID: P705
  value: ENSRNOP00000023152
confidence:
  popularity graph score:
    score: 0.002
    score pct: 0
    tier: established
    components:
      sitelinks: 0
      sitelinks norm: 0.0
      unique citations: 11
      unique citations norm: 0.004
      monthly pageviews: 0
      monthly pageviews norm: 0.0
  sitelinks: 0
  unique citations: 11
  monthly pageviews: 0
  yearly pageviews: 0
  tier: established
claims:
  P31:
    value: Q8054
    source count: 1
    confidence: 0.2
    value label: protein
  P352:
    value: P17178
    source count: 1
    confidence: 0.2
  P361:
    value: Q41797511
    source count: 1
    confidence: 0.2
    value label: cytochrome P450 superfamily
  P361:
    value: Q24741990
    source count: 1
    confidence: 0.2
    value label: cytochrome P450, E-class, group I
  P361:
    value: Q423042
    source count: 1
    confidence: 0.2
    value label: membrane protein
  P361:
    value: Q95352863
    source count: 1
    confidence: 0.2
    value label: cytochrome P450, conserved site, protein family
  P527:
    value: Q24724586
    source count: 1
    confidence: 0.2
    value label: cytochrome P450, conserved site
  P637:
    value: NP_849178
    source count: 1
    confidence: 0.2
  P637:
    value: XP_038939288
    source count: 1
    confidence: 0.2
  P680:
    value: Q14358814
    source count: 1
    confidence: 0.2
    value label: monooxygenase activity
  P680:
    value: Q14358439
    source count: 1
    confidence: 0.2
    value label: iron ion binding
  P680:
    value: Q14349613
    source count: 1
    confidence: 0.2
    value label: oxidoreductase activity
  P680:
    value: Q14358843
    source count: 1
    confidence: 0.2
    value label: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
  P680:
    value: Q14358516
    source count: 1
    confidence: 0.2
    value label: heme binding
  P681:
    value: Q39572
    source count: 2
    confidence: 0.4
    value label: mitochondrion
  P681:
    value: Q14860947
    source count: 1
    confidence: 0.2
    value label: mitochondrial envelope
  P681:
    value: Q14349455
    source count: 1
    confidence: 0.2
    value label: membrane
  P681:
    value: Q14860954
    source count: 1
    confidence: 0.2
    value label: mitochondrial membranes
  P681:
    value: Q14330614
    source count: 1
    confidence: 0.2
    value label: mitochondrial inner membrane
  P682:
    value: Q14864411
    source count: 1
    confidence: 0.2
    value label: steroid catabolic process
  P682:
    value: Q14599650
    source count: 1
    confidence: 0.2
    value label: cholesterol metabolic process
  P682:
    value: Q14905955
    source count: 1
    confidence: 0.2
    value label: calcitriol biosynthetic process from calciol
  P682:
    value: Q14884776
    source count: 1
    confidence: 0.2
    value label: bile acid biosynthetic process
  P682:
    value: Q14358861
    source count: 1
    confidence: 0.2
    value label: C21-steroid hormone biosynthetic process
  P702:
    value: Q24392074
    source count: 1
    confidence: 0.2
    value label: Cyp27a1

value: Q184224
source count: 1
confidence: 0.2
value label: brown rat

value: ENSRNOP00000023152
source count: 1
confidence: 0.2

source: GOA
stated in qid: Q28018111
retrieved: 2019-02-14

source: GOA
stated in qid: Q28018111
retrieved: 2018-01-01

source: A cDNA encoding a rat mitochondrial cytochrome P450 catalyzing both the 26-hydroxylation of cholesterol and 25-hydroxylation of vitamin D3: gonadotropic regulation of the cognate mRNA in ovaries
stated in qid: Q28567277
retrieved: 2019-02-14

source: Mitochondrial targeting of cytochrome P450 proteins containing NH2-terminal chimeric signals involves an unusual TOM20/TOM22 bypass mechanism
stated in qid: Q42675176
retrieved: 2019-02-14

source: The upstream open reading frame mediates constitutive effects on translation of cytochrome p-450c27 from the seventh in-frame AUG codon in rat liver
stated in qid: Q28568176
retrieved: 2019-02-14

source: Mitochondrial targeting of cytochrome P450 proteins containing NH2-terminal chimeric signals involves an unusual TOM20/TOM22 bypass mechanism
stated in qid: Q42675176
retrieved: 2019-01-14

source: A cDNA encoding a rat mitochondrial cytochrome P450 catalyzing both the 26-hydroxylation of cholesterol and 25-hydroxylation of vitamin D3: gonadotropic regulation of the cognate mRNA in ovaries
stated in qid: Q28567277
retrieved: 2019-01-14

source: InterPro Release 71.0
stated in qid: Q58943792

source: UniProt
stated in qid: Q905695
retrieved: 2022-05-25

source: Q20641742
stated in qid: Q20641742
retrieved: 2022-03-20

source: ensembl Release 106
stated in qid: Q111699881

wikidata id: Q28561710
domain: protein
level: standard
html url: https://4ort.xyz/entity/cytochrome-p450-family-27-subfamily-a-polypeptide-1
markdown url: https://4ort.xyz/entity/cytochrome-p450-family-27-subfamily-a-polypeptide-1.md
facts url summary: https://4ort.xyz/entity/cytochrome-p450-family-27-subfamily-a-polypeptide-1/facts.json
facts url standard: https://4ort.xyz/entity/cytochrome-p450-family-27-subfamily-a-polypeptide-1/facts.json
facts url full: https://4ort.xyz/entity/cytochrome-p450-family-27-subfamily-a-polypeptide-1/facts.json
data source: Wikidata (CC0 / public domain)
license: https://creativecommons.org/publicdomain/zero/1.0/
api version: v1
served at: 2026-08-10T01:05:49.511208Z
entity updated at: 2026-05-03T18:28:36.114423+00:00Z
entity created at: 2026-05-03T14:13:20.947238+00:00Z