Cytochrome P450, family 24, subfamily a, polypeptide 1
type: Thing
description: mammalian protein found in Rattus norvegicus
additional property: PropertyValue
  property ID: P31
  value: protein
additional property: PropertyValue
  property ID: P279
  value: protein
additional property: PropertyValue
  property ID: P361
  value: cytochrome P450 superfamily
additional property: PropertyValue
  property ID: P361
  value: Cytochrome P450, E-class, CYP24A, mitochondrial
additional property: PropertyValue
  property ID: P361
  value: cytochrome P450, conserved site, protein family
additional property: PropertyValue
  property ID: P527
  value: cytochrome P450, conserved site
additional property: PropertyValue
  property ID: P637
  value: NP_963966
additional property: PropertyValue
  property ID: P680
  value: monooxygenase activity
additional property: PropertyValue
  property ID: P680
  value: iron ion binding
additional property: PropertyValue
  property ID: P680
  value: 25-hydroxycholecalciferol-24-hydroxylase activity
additional property: PropertyValue
  property ID: P681
  value: nucleus
additional property: PropertyValue
  property ID: P681
  value: nucleoplasm
additional property: PropertyValue
  property ID: P681
  value: mitochondrion
additional property: PropertyValue
  property ID: P682
  value: osteoblast differentiation
additional property: PropertyValue
  property ID: P682
  value: response to vitamin D
additional property: PropertyValue
  property ID: P682
  value: vitamin D metabolic process
additional property: PropertyValue
  property ID: P702
  value: Cyp24a1
additional property: PropertyValue
  property ID: P703
  value: brown rat
additional property: PropertyValue
  property ID: P705
  value: ENSRNOP00000043298
additional property: PropertyValue
  property ID: P705
  value: ENSRNOP00000089650
confidence:
  popularity graph score:
    score: 0.001
    score pct: 0
    tier: established
    components:
      sitelinks: 0
      sitelinks norm: 0.0
      unique citations: 9
      unique citations norm: 0.004
      monthly pageviews: 0
      monthly pageviews norm: 0.0
  sitelinks: 0
  unique citations: 9
  monthly pageviews: 0
  yearly pageviews: 0
  tier: established
claims:
  P31:
    value: Q8054
    source count: 1
    confidence: 0.2
    value label: protein
  P279:
    value: Q8054
    source count: 1
    confidence: 0.2
    value label: protein
  P352:
    value: Q09128
    source count: 1
    confidence: 0.2
  P361:
    value: Q41797511
    source count: 1
    confidence: 0.2
    value label: cytochrome P450 superfamily
  P361:
    value: Q24785227
    source count: 1
    confidence: 0.2
    value label: Cytochrome P450, E-class, CYP24A, mitochondrial
  P361:
    value: Q95352863
    source count: 1
    confidence: 0.2
    value label: cytochrome P450, conserved site, protein family
  P527:
    value: Q24724586
    source count: 1
    confidence: 0.2
    value label: cytochrome P450, conserved site
  P637:
    value: NP_963966
    source count: 1
    confidence: 0.2
  P680:
    value: Q14358814
    source count: 1
    confidence: 0.2
    value label: monooxygenase activity
  P680:
    value: Q14358439
    source count: 1
    confidence: 0.2
    value label: iron ion binding
  P680:
    value: Q21110755
    source count: 3
    confidence: 0.6
    value label: 25-hydroxycholecalciferol-24-hydroxylase activity
  P680:
    value: Q14349613
    source count: 1
    confidence: 0.2
    value label: oxidoreductase activity
  P680:
    value: Q14358843
    source count: 1
    confidence: 0.2
    value label: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
  P681:
    value: Q40260
    source count: 1
    confidence: 0.2
    value label: nucleus
  P681:
    value: Q14817956
    source count: 1
    confidence: 0.2
    value label: nucleoplasm
  P681:
    value: Q39572
    source count: 3
    confidence: 0.6
    value label: mitochondrion
  P681:
    value: Q29548
    source count: 1
    confidence: 0.2
    value label: plasma membrane
  P682:
    value: Q14876609
    source count: 1
    confidence: 0.2
    value label: osteoblast differentiation
  P682:
    value: Q14599705
    source count: 1
    confidence: 0.2
    value label: response to vitamin D
  P682:
    value: Q14599717
    source count: 3
    confidence: 0.6
    value label: vitamin D metabolic process
  P682:
    value: Q14599725
    source count: 1
    confidence: 0.2
    value label: vitamin D catabolic process
  P702:
    value: Q24392416
    source count: 1
    confidence: 0.2
    value label: Cyp24a1
  P703:
    value: Q184224
    source count: 1
    confidence: 0.2
    value label: brown rat
  P705:
    value: ENSRNOP00000043298
    source count: 1
    confidence: 0.2
  P705:
    value: ENSRNOP00000089650
    source count: 1
    confidence: 0.2

source: GOA
stated in qid: Q28018111
retrieved: 2019-02-14

source: Characterization of transgenic rats constitutively expressing vitamin D-24-hydroxylase gene
stated in qid: Q28575018
retrieved: 2019-02-14

source: Cloning and expression of cDNA encoding 25-hydroxyvitamin D3 24-hydroxylase
stated in qid: Q28577908
retrieved: 2019-02-14

source: The 25-Hydroxyvitamin D 1-Alpha-Hydroxylase Gene Maps to the Pseudovitamin D-Deficiency Rickets (PDDR) Disease Locus
stated in qid: Q24318580
retrieved: 2019-02-14

source: Role of MAP kinases in the 1,25-dihydroxyvitamin D3-induced transactivation of the rat cytochrome P450C24 (CYP24) promoter. Specific functions for ERK1/ERK2 and ERK5
stated in qid: Q28564938
retrieved: 2019-02-14

source: InterPro Release 71.0
stated in qid: Q58943792

source: UniProt
stated in qid: Q905695
retrieved: 2022-05-25

source: Q20641742
stated in qid: Q20641742
retrieved: 2022-03-20

source: ensembl Release 106
stated in qid: Q111699881

wikidata id: Q28563298
domain: protein
level: standard
html url: https://4ort.xyz/entity/cytochrome-p450-family-24-subfamily-a-polypeptide-1-q28563298
markdown url: https://4ort.xyz/entity/cytochrome-p450-family-24-subfamily-a-polypeptide-1-q28563298.md
facts url summary: https://4ort.xyz/entity/cytochrome-p450-family-24-subfamily-a-polypeptide-1-q28563298/facts.json
facts url standard: https://4ort.xyz/entity/cytochrome-p450-family-24-subfamily-a-polypeptide-1-q28563298/facts.json
facts url full: https://4ort.xyz/entity/cytochrome-p450-family-24-subfamily-a-polypeptide-1-q28563298/facts.json
data source: Wikidata (CC0 / public domain)
license: https://creativecommons.org/publicdomain/zero/1.0/
api version: v1
served at: 2026-08-13T11:07:01.588001Z
entity updated at: 2026-05-03T18:28:36.114423+00:00Z
entity created at: 2026-05-03T13:59:55.134900+00:00Z