cytochrome P450 family 2 subfamily E member 1
type: Thing
description: mammalian protein found in Homo sapiens
additional property: PropertyValue
  property ID: P31
  value: protein
additional property: PropertyValue
  property ID: P352
  value: P05181
additional property: PropertyValue
  property ID: P361
  value: cytochrome P450 superfamily
additional property: PropertyValue
  property ID: P361
  value: Cytochrome P450, E-class, group I, CYP2E-like
additional property: PropertyValue
  property ID: P361
  value: cytochrome P450, conserved site, protein family
additional property: PropertyValue
  property ID: P486
  value: D019392
additional property: PropertyValue
  property ID: P527
  value: cytochrome P450, conserved site
additional property: PropertyValue
  property ID: P591
  value: 1.14.13.n7
additional property: PropertyValue
  property ID: P637
  value: NP_000764
additional property: PropertyValue
  property ID: P638
  value: 3E4E
additional property: PropertyValue
  property ID: P638
  value: 3E6I
additional property: PropertyValue
  property ID: P638
  value: 3GPH
additional property: PropertyValue
  property ID: P646
  value: /m/03_9bc
additional property: PropertyValue
  property ID: P672
  value: D08.244.453.491.375
additional property: PropertyValue
  property ID: P672
  value: D08.811.682.662.582.338
additional property: PropertyValue
  property ID: P672
  value: D08.811.682.690.708.170.450.375
additional property: PropertyValue
  property ID: P680
  value: iron ion binding
additional property: PropertyValue
  property ID: P680
  value: oxygen binding
additional property: PropertyValue
  property ID: P680
  value: arachidonic acid epoxygenase activity
additional property: PropertyValue
  property ID: P681
  value: organelle membrane
additional property: PropertyValue
  property ID: P681
  value: endoplasmic reticulum membrane
additional property: PropertyValue
  property ID: P681
  value: intracellular membrane-bounded organelle
additional property: PropertyValue
  property ID: P682
  value: steroid metabolic process
additional property: PropertyValue
  property ID: P682
  value: epoxygenase P450 pathway
additional property: PropertyValue
  property ID: P682
  value: response to ozone
additional property: PropertyValue
  property ID: P692
  value: PBB GE CYP2E1 1431 at fs.png
additional property: PropertyValue
  property ID: P702
  value: CYP2E1
additional property: PropertyValue
  property ID: P703
  value: Homo sapiens
additional property: PropertyValue
  property ID: P705
  value: ENSP00000252945
additional property: PropertyValue
  property ID: P705
  value: ENSP00000440689
confidence:
  popularity graph score:
    score: 0.003
    score pct: 0
    tier: established
    components:
      sitelinks: 0
      sitelinks norm: 0.0
      unique citations: 20
      unique citations norm: 0.008
      monthly pageviews: 0
      monthly pageviews norm: 0.0
  sitelinks: 0
  unique citations: 20
  monthly pageviews: 0
  yearly pageviews: 0
  tier: established
claims:
  P31:
    value: Q8054
    source count: 1
    confidence: 0.2
    value label: protein
  P352:
    value: P05181
    source count: 1
    confidence: 0.2
  P361:
    value: Q41797511
    source count: 1
    confidence: 0.2
    value label: cytochrome P450 superfamily
  P361:
    value: Q24773577
    source count: 1
    confidence: 0.2
    value label: Cytochrome P450, E-class, group I, CYP2E-like
  P361:
    value: Q95352863
    source count: 1
    confidence: 0.2
    value label: cytochrome P450, conserved site, protein family
  P486:
    value: D019392
    source count: 0
    confidence: 0.0
  P527:
    value: Q24724586
    source count: 1
    confidence: 0.2
    value label: cytochrome P450, conserved site
  P591:
    value: 1.14.13.n7
    source count: 2
    confidence: 0.4
  P637:
    value: NP_000764
    source count: 1
    confidence: 0.2
  P638:
    value: 3E4E
    source count: 1
    confidence: 0.2
  P638:
    value: 3E6I
    source count: 1
    confidence: 0.2
  P638:
    value: 3GPH
    source count: 1
    confidence: 0.2
  P638:
    value: 3KOH
    source count: 1
    confidence: 0.2
  P638:
    value: 3LC4
    source count: 1
    confidence: 0.2
  P646:
    value: /m/03_9bc
    source count: 1
    confidence: 0.2
  P672:
    value: D08.244.453.491.375
    source count: 0
    confidence: 0.0
  P672:
    value: D08.811.682.662.582.338
    source count: 0
    confidence: 0.0
  P672:
    value: D08.811.682.690.708.170.450.375
    source count: 0
    confidence: 0.0
  P672:
    value: D12.776.422.220.453.491.375
    source count: 0
    confidence: 0.0
  P680:
    value: Q14358439
    source count: 1
    confidence: 0.2
    value label: iron ion binding
  P680:
    value: Q14819285
    source count: 1
    confidence: 0.2
    value label: oxygen binding

value: Q21095362
source count: 1
confidence: 0.2
value label: arachidonic acid epoxygenase activity

value: Q14864403
source count: 2
confidence: 0.4
value label: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen

value: Q13667380
source count: 1
confidence: 0.2
value label: metal ion binding

value: Q14878067
source count: 1
confidence: 0.2
value label: organelle membrane

value: Q14329032
source count: 3
confidence: 0.6
value label: endoplasmic reticulum membrane

value: Q14349519
source count: 2
confidence: 0.4
value label: intracellular membrane-bounded organelle

value: Q14349455
source count: 1
confidence: 0.2
value label: membrane

value: Q14864430
source count: 1
confidence: 0.2
value label: intrinsic component of endoplasmic reticulum membrane

value: Q14327702
source count: 1
confidence: 0.2
value label: steroid metabolic process

value: Q14890098
source count: 1
confidence: 0.2
value label: epoxygenase P450 pathway

value: Q14864432
source count: 1
confidence: 0.2
value label: response to ozone

value: Q14864417
source count: 1
confidence: 0.2
value label: heterocycle metabolic process

value: Q14864433
source count: 1
confidence: 0.2
value label: response to organonitrogen compound

value: PBB GE CYP2E1 1431 at fs.png
source count: 0
confidence: 0.0

value: Q14864434
source count: 1
confidence: 0.2
value label: CYP2E1

value: Q15978631
source count: 1
confidence: 0.2
value label: Homo sapiens

value: ENSP00000252945
source count: 1
confidence: 0.2

value: ENSP00000440689
source count: 1
confidence: 0.2

value: ENSP00000397299
source count: 1
confidence: 0.2

value: ENSP00000412754
source count: 1
confidence: 0.2

value: ENSP00000437799
source count: 1
confidence: 0.2

value: https://identifiers.org/uniprot:P05181
source count: 1
confidence: 0.2

value: http://purl.uniprot.org/uniprot/P05181
source count: 1
confidence: 0.2

value: https://www.ncbi.nlm.nih.gov/protein/P05181
source count: 1
confidence: 0.2

value: C0010763
source count: 1
confidence: 0.2

source: UniProt
stated in qid: Q905695
retrieved: 2015-10-12

source: Swiss-Prot
stated in qid: Q2629752
retrieved: 2015-11-14

source: GOA
stated in qid: Q28018111
retrieved: 2019-04-08

source: Human ethanol-inducible P450IIE1: complete gene sequence, promoter characterization, chromosome mapping, and cDNA-directed expression
stated in qid: Q24297484
retrieved: 2019-04-08

source: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
stated in qid: Q34211397
retrieved: 2019-04-08

source: GOA
stated in qid: Q28018111
retrieved: 2018-06-21

source: Hepatic cytochrome P450 enzyme alterations in humans with progressive stages of nonalcoholic fatty liver disease
stated in qid: Q24319917
retrieved: 2019-04-08

source: Structures of human cytochrome P-450 2E1. Insights into the binding of inhibitors and both small molecular weight and fatty acid substrates
stated in qid: Q24316102
retrieved: 2018-06-21

source: Interactions of mammalian cytochrome P450, NADPH-cytochrome P450 reductase, and cytochrome b(5) enzymes
stated in qid: Q24293148
retrieved: 2019-04-08

source: Radical intermediates in the catalytic oxidation of hydrocarbons by bacterial and human cytochrome P450 enzymes
stated in qid: Q24300576
retrieved: 2019-04-08

source: Acetaminophen bioactivation by human cytochrome P450 enzymes and animal microsomes
stated in qid: Q24311331
retrieved: 2019-04-08

source: Structures of human cytochrome P-450 2E1. Insights into the binding of inhibitors and both small molecular weight and fatty acid substrates
stated in qid: Q24316102
retrieved: 2019-04-08

source: Identification of the human cytochrome P450 enzymes involved in the in vitro biotransformation of lynestrenol and norethindrone
stated in qid: Q24313179
retrieved: 2019-04-08

source: InterPro Release 71.0
stated in qid: Q58943792

source: Identifiers.org
stated in qid: Q16335163

source: Freebase Data Dumps
stated in qid: Q15241312
pub year: 2013

source: UniProt
stated in qid: Q905695
retrieved: 2019-11-13

source: Q20641742
stated in qid: Q20641742
retrieved: 2020-05-30

source: UMLS 2023
stated in qid: Q118645236
retrieved: 2023-05-24

source: Ensembl Release 99
stated in qid: Q83867711

wikidata id: Q4210020
domain: protein
level: standard
html url: https://4ort.xyz/entity/cytochrome-p450-family-2-subfamily-e-member-1
markdown url: https://4ort.xyz/entity/cytochrome-p450-family-2-subfamily-e-member-1.md
facts url summary: https://4ort.xyz/entity/cytochrome-p450-family-2-subfamily-e-member-1/facts.json
facts url standard: https://4ort.xyz/entity/cytochrome-p450-family-2-subfamily-e-member-1/facts.json
facts url full: https://4ort.xyz/entity/cytochrome-p450-family-2-subfamily-e-member-1/facts.json
data source: Wikidata (CC0 / public domain)
license: https://creativecommons.org/publicdomain/zero/1.0/
api version: v1
served at: 2026-08-08T22:30:16.966901Z
entity updated at: 2026-05-03T18:28:36.114423+00:00Z
entity created at: 2026-05-03T13:44:08.782628+00:00Z