# cytochrome P450 family 17 subfamily A member 1

> mammalian protein found in Homo sapiens

**Wikidata**: [Q408305](https://www.wikidata.org/wiki/Q408305)  
**Wikipedia**: [English](https://en.wikipedia.org/wiki/CYP17A1)  
**Source**: https://4ort.xyz/entity/cytochrome-p450-family-17-subfamily-a-member-1


## References

1. UniProt
2. IUPHAR/BPS Guide to PHARMACOLOGY
3. [Open Targets Platform](https://platform.opentargets.org/drug/CHEMBL3264610)
4. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P05093)
5. Q20641742
6. Freebase Data Dumps. 2013
7. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05093)
8. [Deletion of a phenylalanine in the N-terminal region of human cytochrome P-450(17 alpha) results in partial combined 17 alpha-hydroxylase/17,20-lyase deficiency](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05093)
9. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P05093&geneProductId=UniProtKB:P05093)
10. [Identification by molecular cloning of an autoantigen associated with Addison's disease as steroid 17 alpha-hydroxylase](http://www.ebi.ac.uk/QuickGO/annotations?protein=P05093&geneProductId=UniProtKB:P05093)
11. [A review of the literature on common CYP17A1 mutations in adults with 17-hydroxylase/17,20-lyase deficiency, a case series of such mutations among Koreans and functional characteristics of a novel mutation](http://www.ebi.ac.uk/QuickGO/annotations?protein=P05093&geneProductId=UniProtKB:P05093)
12. [A missense mutation in the human cytochrome b5 gene causes 46,XY disorder of sex development due to true isolated 17,20 lyase deficiency](http://www.ebi.ac.uk/QuickGO/annotations?protein=P05093&geneProductId=UniProtKB:P05093)
13. [Structures of cytochrome P450 17A1 with prostate cancer drugs abiraterone and TOK-001](http://www.ebi.ac.uk/QuickGO/annotations?protein=P05093&geneProductId=UniProtKB:P05093)
14. [Structures of cytochrome P450 17A1 with prostate cancer drugs abiraterone and TOK-001](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05093)
15. [Identification by molecular cloning of an autoantigen associated with Addison's disease as steroid 17 alpha-hydroxylase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05093)
16. [A review of the literature on common CYP17A1 mutations in adults with 17-hydroxylase/17,20-lyase deficiency, a case series of such mutations among Koreans and functional characteristics of a novel mutation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05093)
17. [A missense mutation in the human cytochrome b5 gene causes 46,XY disorder of sex development due to true isolated 17,20 lyase deficiency](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05093)
18. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05093)
19. [The genetic and functional basis of isolated 17,20-lyase deficiency](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05093)
20. [Cloning and sequence of the human gene for P450c17 (steroid 17 alpha-hydroxylase/17,20 lyase): similarity with the gene for P450c21](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05093)
21. Ensembl Release 99
22. Identifiers.org
23. [OpenAlex](https://docs.openalex.org/download-snapshot/snapshot-data-format)