Cytochrome P450, family 11, subfamily b, polypeptide 2
type: Thing
description: mammalian protein found in Mus musculus
additional property: PropertyValue
  property ID: P31
  value: protein
additional property: PropertyValue
  property ID: P352
  value: P15539
additional property: PropertyValue
  property ID: P361
  value: cytochrome P450 superfamily
additional property: PropertyValue
  property ID: P361
  value: cytochrome P450, mitochondrial
additional property: PropertyValue
  property ID: P361
  value: membrane protein
additional property: PropertyValue
  property ID: P527
  value: cytochrome P450, conserved site
additional property: PropertyValue
  property ID: P637
  value: NP_034121
additional property: PropertyValue
  property ID: P680
  value: iron ion binding
additional property: PropertyValue
  property ID: P680
  value: steroid 11-beta-monooxygenase activity
additional property: PropertyValue
  property ID: P680
  value: metal ion binding
additional property: PropertyValue
  property ID: P681
  value: membrane
additional property: PropertyValue
  property ID: P681
  value: mitochondrial membranes
additional property: PropertyValue
  property ID: P681
  value: mitochondrion
additional property: PropertyValue
  property ID: P682
  value: ion homeostasis
additional property: PropertyValue
  property ID: P682
  value: aldosterone biosynthetic process
additional property: PropertyValue
  property ID: P682
  value: cortisol biosynthetic process
additional property: PropertyValue
  property ID: P702
  value: Cyp11b2
additional property: PropertyValue
  property ID: P703
  value: house mouse
additional property: PropertyValue
  property ID: P705
  value: ENSMUSP00000131503
additional property: PropertyValue
  property ID: P705
  value: ENSMUSP00000158954
confidence:
  popularity graph score:
    score: 0.002
    score pct: 0
    tier: established
    components:
      sitelinks: 0
      sitelinks norm: 0.0
      unique citations: 16
      unique citations norm: 0.006
      monthly pageviews: 0
      monthly pageviews norm: 0.0
  sitelinks: 0
  unique citations: 16
  monthly pageviews: 0
  yearly pageviews: 0
  tier: established
claims:
  P31:
    value: Q8054
    source count: 1
    confidence: 0.2
    value label: protein
  P352:
    value: P15539
    source count: 1
    confidence: 0.2
  P361:
    value: Q41797511
    source count: 1
    confidence: 0.2
    value label: cytochrome P450 superfamily
  P361:
    value: Q24727817
    source count: 1
    confidence: 0.2
    value label: cytochrome P450, mitochondrial
  P361:
    value: Q423042
    source count: 1
    confidence: 0.2
    value label: membrane protein
  P361:
    value: Q95352863
    source count: 1
    confidence: 0.2
    value label: cytochrome P450, conserved site, protein family
  P527:
    value: Q24724586
    source count: 1
    confidence: 0.2
    value label: cytochrome P450, conserved site
  P637:
    value: NP_034121
    source count: 1
    confidence: 0.2
  P680:
    value: Q14358439
    source count: 1
    confidence: 0.2
    value label: iron ion binding
  P680:
    value: Q14904975
    source count: 4
    confidence: 0.8
    value label: steroid 11-beta-monooxygenase activity
  P680:
    value: Q13667380
    source count: 1
    confidence: 0.2
    value label: metal ion binding
  P680:
    value: Q14358814
    source count: 2
    confidence: 0.4
    value label: monooxygenase activity
  P680:
    value: Q14358843
    source count: 1
    confidence: 0.2
    value label: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
  P681:
    value: Q14349455
    source count: 1
    confidence: 0.2
    value label: membrane
  P681:
    value: Q14860954
    source count: 1
    confidence: 0.2
    value label: mitochondrial membranes
  P681:
    value: Q39572
    source count: 5
    confidence: 1.0
    value label: mitochondrion
  P681:
    value: Q39572
    source count: 5
    confidence: 1.0
    value label: mitochondrion
  P681:
    value: Q14330614
    source count: 1
    confidence: 0.2
    value label: mitochondrial inner membrane
  P682:
    value: Q14819888
    source count: 1
    confidence: 0.2
    value label: ion homeostasis
  P682:
    value: Q14904978
    source count: 3
    confidence: 0.6
    value label: aldosterone biosynthetic process
  P682:
    value: Q14904979
    source count: 1
    confidence: 0.2
    value label: cortisol biosynthetic process
  P682:
    value: Q14819786
    source count: 1
    confidence: 0.2
    value label: regulation of blood pressure
  P682:
    value: Q14358861
    source count: 1
    confidence: 0.2
    value label: C21-steroid hormone biosynthetic process
  P702:
    value: Q14907855
    source count: 1
    confidence: 0.2
    value label: Cyp11b2
  P703:
    value: Q83310
    source count: 1
    confidence: 0.2
    value label: house mouse

value: ENSMUSP00000131503
source count: 1
confidence: 0.2

value: ENSMUSP00000158954
source count: 1
confidence: 0.2

source: GOA
stated in qid: Q28018111
retrieved: 2019-02-14

source: GOA
stated in qid: Q28018111
retrieved: 2017-09-16

source: Different isozymes of mouse 11 beta-hydroxylase produce mineralocorticoids and glucocorticoids
stated in qid: Q28585760
retrieved: 2017-09-16

source: The hamster adrenal cytochrome P450C11 has equipotent 11beta-hydroxylase and 19-hydroxylase activities, but no aldosterone synthase activity
stated in qid: Q28587043
retrieved: 2017-09-16

source: Different isozymes of mouse 11 beta-hydroxylase produce mineralocorticoids and glucocorticoids
stated in qid: Q28585760
retrieved: 2019-02-14

source: The hamster adrenal cytochrome P450C11 has equipotent 11beta-hydroxylase and 19-hydroxylase activities, but no aldosterone synthase activity
stated in qid: Q28587043
retrieved: 2019-02-14

source: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
stated in qid: Q34211397
retrieved: 2019-02-14

source: A mitochondrial protein compendium elucidates complex I disease biology
stated in qid: Q24655079
retrieved: 2017-09-16

source: Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria
stated in qid: Q28593536
retrieved: 2017-09-16

source: Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria
stated in qid: Q28593536
retrieved: 2019-02-14

source: A mitochondrial protein compendium elucidates complex I disease biology
stated in qid: Q24655079
retrieved: 2019-02-14

source: Kidney function in mice lacking aldosterone
stated in qid: Q28508621
retrieved: 2019-02-14

source: InterPro Release 71.0
stated in qid: Q58943792

source: UniProt
stated in qid: Q905695
retrieved: 2022-05-25

source: Q20641742
stated in qid: Q20641742
retrieved: 2022-03-20

source: ensembl Release 106
stated in qid: Q111699881

wikidata id: Q14907857
domain: protein
level: standard
html url: https://4ort.xyz/entity/cytochrome-p450-family-11-subfamily-b-polypeptide-2
markdown url: https://4ort.xyz/entity/cytochrome-p450-family-11-subfamily-b-polypeptide-2.md
facts url summary: https://4ort.xyz/entity/cytochrome-p450-family-11-subfamily-b-polypeptide-2/facts.json
facts url standard: https://4ort.xyz/entity/cytochrome-p450-family-11-subfamily-b-polypeptide-2/facts.json
facts url full: https://4ort.xyz/entity/cytochrome-p450-family-11-subfamily-b-polypeptide-2/facts.json
data source: Wikidata (CC0 / public domain)
license: https://creativecommons.org/publicdomain/zero/1.0/
api version: v1
served at: 2026-08-07T03:33:42.517042Z
entity updated at: 2026-05-03T18:28:36.114423+00:00Z
entity created at: 2026-05-03T15:24:30.033700+00:00Z