# Cytochrome P450, family 11, subfamily a, polypeptide 1

> mammalian protein found in Rattus norvegicus

**Wikidata**: [Q28557080](https://www.wikidata.org/wiki/Q28557080)  
**Source**: https://4ort.xyz/entity/cytochrome-p450-family-11-subfamily-a-polypeptide-1-q28557080


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P14137)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14137)
5. [Transcription of cholesterol side-chain cleavage cytochrome P450 in the placenta: activating protein-2 assumes the role of steroidogenic factor-1 by binding to an overlapping promoter element](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14137)
6. [In vivo exposure of young adult male rats to methoxychlor reduces serum testosterone levels and ex vivo Leydig cell testosterone formation and cholesterol side-chain cleavage activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14137)
7. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14137)
8. [Induction and mitochondrial localization of cytochrome P450scc system enzymes in normal and transformed ovarian granulosa cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14137)
9. [Ontogeny of immunoreactive and bioactive microsomal steroidogenic enzymes during adrenocortical development in rats](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14137)
10. [Localization and functional activity of cytochrome P450 side chain cleavage enzyme (CYP11A1) in the adult rat kidney](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14137)
11. [Immunoelectron microscopic localization of three key steroidogenic enzymes (cytochrome P450(scc), 3 beta-hydroxysteroid dehydrogenase and cytochrome P450(c17)) in rat adrenal cortex and gonads](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14137)
12. [Neurogenic pain and steroid synthesis in the spinal cord](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14137)
13. [Alterations in gene expression and testosterone synthesis in the testes of male rats exposed to perfluorododecanoic acid](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14137)
14. [Luteinizing hormone-induced caspase activation in rat preovulatory follicles is coupled to mitochondrial steroidogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14137)
15. [Development of relevant assay system to identify steroidogenic enzyme inhibitors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14137)
16. [Vitamin K deficiency reduces testosterone production in the testis through down-regulation of the Cyp11a a cholesterol side chain cleavage enzyme in rats](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14137)
17. [Inhibiting biosynthesis and/or metabolism of progestins in the ventral tegmental area attenuates lordosis of rats in behavioural oestrus](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14137)
18. [Antiandrogen exposure in utero disrupts expression of desert hedgehog and insulin-like factor 3 in the developing fetal rat testis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14137)
19. [Transcriptional activation of adrenocortical steroidogenic genes by high potassium or low sodium intake](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14137)
20. [Spearmint induced hypothalamic oxidative stress and testicular anti-androgenicity in male rats - altered levels of gene expression, enzymes and hormones](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14137)
21. [Contamination with depleted or enriched uranium differently affects steroidogenesis metabolism in rat](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14137)
22. [In vivo effects of chronic contamination with 137 cesium on testicular and adrenal steroidogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14137)
23. [Regulatory role of cytochrome P450scc and pregnenolone in myelination by rat Schwann cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14137)
24. [Effects of endocrine disrupting chemicals from leather industry effluents on male reproductive system](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14137)
25. [Fenvalerate inhibits the growth of primary cultured rat preantral ovarian follicles](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14137)
26. [Polychlorinated biphenyls have inhibitory effect on testicular steroidogenesis by downregulation of P45017α and P450scc](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14137)
27. [Studies on the protective role of lycopene against polychlorinated biphenyls (Aroclor 1254)-induced changes in StAR protein and cytochrome P450 scc enzyme expression on Leydig cells of adult rats](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14137)
28. [The effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on foetal male rat steroidogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14137)
29. [Effect of bisphenol A on steroid hormone production in rat ovarian theca-interstitial and granulosa cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14137)
30. [Time-response effects of testicular gene expression profiles in Sprague-Dawley male rats treated with di(n-butyl) phthalate](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14137)
31. [Sex differences, developmental changes, response to injury and cAMP regulation of the mRNA levels of steroidogenic acute regulatory protein, cytochrome p450scc, and aromatase in the olivocerebellar system](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14137)
32. [Semicomprehensive analysis of the postnatal age-related changes in the mRNA expression of sex steroidogenic enzymes and sex steroid receptors in the male rat hippocampus](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14137)
33. [Effects of vitamins C and E on steroidogenic enzymes mRNA expression in polychlorinated biphenyl (Aroclor 1254) exposed adult rat Leydig cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14137)
34. [Leydig cell re-generation and expression of cell signaling molecules in the germ cell-free testis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14137)
35. [Influence of long-term dietary administration of procymidone, a fungicide with anti-androgenic effects, or the phytoestrogen genistein to rats on the pituitary-gonadal axis and Leydig cell steroidogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14137)
36. [Interferon-alpha is involved in the luteinizing hormone-induced differentiation of rat preovulatory granulosa cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14137)
37. [Antisteroidogenic actions of hydrogen peroxide on rat Leydig cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14137)
38. [Changes in cytochrome P450 side chain cleavage expression in the rat hippocampus after kainate injury](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14137)
39. [Differences in adrenocortical secretory and gene expression responses to stimulation in vitro by ACTH or prolactin between high- and low-avoidance Hatano rats](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14137)
40. [Effects of maternal exposure to low doses of DES on testicular steroidogenesis and spermatogenesis in male rat offspring](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14137)
41. [Exposure of neonatal rats to diethylstilbestrol affects the expression of genes involved in ovarian differentiation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14137)
42. [Fibroblast growth factor-9, a local regulator of ovarian function](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14137)
43. [Alteration of testicular steroidogenesis and histopathology of reproductive system in male rats treated with triclosan](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14137)
44. [Effect of ascorbic acid supplementation on testicular steroidogenesis and germ cell death in cadmium-treated male rats](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14137)
45. [The expression of serum steroid sex hormones and steroidogenic enzymes following intraperitoneal administration of dehydroepiandrosterone (DHEA) in male rats](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14137)
46. [Effects of corticosterone deficiency and its replacement on Leydig cell steroidogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14137)
47. [Rat cholesterol side-chain cleavage cytochrome P-450 (P-450scc) gene. Structure and regulation by cAMP in vitro](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14137)
48. [Activity and expression of different members of the caspase family in the rat corpus luteum during pregnancy and postpartum](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14137)
49. [Effects of vinclozolin administration on sperm production and testosterone biosynthetic pathway in adult male rat](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14137)
50. [Differential effects of nonylphenol on testosterone secretion in rat Leydig cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14137)