# cytochrome P450, family 1, subfamily a, polypeptide 1

> mammalian protein found in Mus musculus

**Wikidata**: [Q14916463](https://www.wikidata.org/wiki/Q14916463)  
**Source**: https://4ort.xyz/entity/cytochrome-p450-family-1-subfamily-a-polypeptide-1


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P00184)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00184)
5. [Enzyme-kinetic and immunochemical characteristics of mouse cDNA-expressed, microsomal, and purified CYP1A1 and CYP1A2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00184)
6. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P00184&geneProductId=UniProtKB:P00184)
7. [Upregulation of CYP2e1 and CYP3a activities in histamine-deficient histidine decarboxylase gene targeted mice](http://www.ebi.ac.uk/QuickGO/annotations?protein=P00184&geneProductId=UniProtKB:P00184)
8. [Upregulation of CYP2e1 and CYP3a activities in histamine-deficient histidine decarboxylase gene targeted mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00184)
9. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00184)
10. [7H-dibenzo[c,g]carbazole metabolism by the mouse and human CYP1 family of enzymes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00184)
11. [Mouse lung CYP1A1 catalyzes the metabolic activation of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00184)
12. [For dioxin-induced birth defects, mouse or human CYP1A2 in maternal liver protects whereas mouse CYP1A1 and CYP1B1 are inconsequential](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00184)
13. [Cyp1a2 protects against reactive oxygen production in mouse liver microsomes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00184)
14. [Oral benzo[a]pyrene in Cyp1 knockout mouse lines: CYP1A1 important in detoxication, CYP1B1 metabolism required for immune damage independent of total-body burden and clearance rate](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00184)
15. [2,3,7,8-Tetrachlorodibenzo-p-dioxin poly(ADP-ribose) polymerase (TiPARP, ARTD14) is a mono-ADP-ribosyltransferase and repressor of aryl hydrocarbon receptor transactivation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00184)
16. ensembl Release 106