cytochrome c oxidase assembly factor heme A:farnesyltransferase COX10
type: Thing
description: mammalian protein found in Homo sapiens
additional property: PropertyValue
  property ID: P31
  value: protein
additional property: PropertyValue
  property ID: P352
  value: Schaerbeek
additional property: PropertyValue
  property ID: P361
  value: Protohaem IX farnesyltransferase, mitochondria
additional property: PropertyValue
  property ID: P361
  value: UbiA prenyltransferase conserved site, protein family
additional property: PropertyValue
  property ID: P527
  value: UbiA prenyltransferase conserved site
additional property: PropertyValue
  property ID: P637
  value: NP_001294
additional property: PropertyValue
  property ID: P646
  value: /m/03hggbm
additional property: PropertyValue
  property ID: P680
  value: transferase activity
additional property: PropertyValue
  property ID: P680
  value: farnesyltranstransferase activity
additional property: PropertyValue
  property ID: P680
  value: cytochrome-c oxidase activity
additional property: PropertyValue
  property ID: P681
  value: integral component of membrane
additional property: PropertyValue
  property ID: P681
  value: membrane
additional property: PropertyValue
  property ID: P681
  value: mitochondrial membranes
additional property: PropertyValue
  property ID: P682
  value: cytochrome complex assembly
additional property: PropertyValue
  property ID: P682
  value: mitochondrial fission
additional property: PropertyValue
  property ID: P682
  value: mitochondrion organization
additional property: PropertyValue
  property ID: P702
  value: COX10
additional property: PropertyValue
  property ID: P703
  value: Homo sapiens
additional property: PropertyValue
  property ID: P705
  value: ENSP00000261643
additional property: PropertyValue
  property ID: P705
  value: ENSP00000397750
additional property: PropertyValue
  property ID: P705
  value: ENSP00000462190
confidence:
  popularity graph score:
    score: 0.002
    score pct: 0
    tier: established
    components:
      sitelinks: 0
      sitelinks norm: 0.0
      unique citations: 11
      unique citations norm: 0.004
      monthly pageviews: 0
      monthly pageviews norm: 0.0
  sitelinks: 0
  unique citations: 11
  monthly pageviews: 0
  yearly pageviews: 14
  pageview trend:
    m: 2026-06
    v: 13
  pageview trend:
    m: 2026-05
    v: 1
  tier: established
claims:
  P31:
    value: Q8054
    source count: 1
    confidence: 0.2
    value label: protein
  P352:
    value: Q12887
    source count: 1
    confidence: 0.2
    value label: Schaerbeek
  P361:
    value: Q24721135
    source count: 1
    confidence: 0.2
    value label: Protohaem IX farnesyltransferase, mitochondria
  P361:
    value: Q95352573
    source count: 1
    confidence: 0.2
    value label: UbiA prenyltransferase conserved site, protein family
  P527:
    value: Q24779585
    source count: 1
    confidence: 0.2
    value label: UbiA prenyltransferase conserved site
  P637:
    value: NP_001294
    source count: 1
    confidence: 0.2
  P646:
    value: /m/03hggbm
    source count: 0
    confidence: 0.0
  P680:
    value: Q14840131
    source count: 1
    confidence: 0.2
    value label: transferase activity
  P680:
    value: Q21100861
    source count: 1
    confidence: 0.2
    value label: farnesyltranstransferase activity
  P680:
    value: Q14865318
    source count: 1
    confidence: 0.2
    value label: cytochrome-c oxidase activity
  P680:
    value: Q21100862
    source count: 2
    confidence: 0.4
    value label: protoheme IX farnesyltransferase activity
  P680:
    value: Q21117494
    source count: 1
    confidence: 0.2
    value label: transferase activity, transferring alkyl or aryl (other than methyl) groups
  P681:
    value: Q14327652
    source count: 2
    confidence: 0.4
    value label: integral component of membrane
  P681:
    value: Q14349455
    source count: 1
    confidence: 0.2
    value label: membrane
  P681:
    value: Q14860954
    source count: 2
    confidence: 0.4
    value label: mitochondrial membranes
  P681:
    value: Q14901430
    source count: 1
    confidence: 0.2
    value label: cytochrome complex
  P681:
    value: Q14330614
    source count: 1
    confidence: 0.2
    value label: mitochondrial inner membrane
  P682:
    value: Q21109987
    source count: 1
    confidence: 0.2
    value label: cytochrome complex assembly
  P682:
    value: Q6881852
    source count: 1
    confidence: 0.2
    value label: mitochondrial fission
  P682:
    value: Q14882521
    source count: 1
    confidence: 0.2
    value label: mitochondrion organization
  P682:
    value: Q14885223
    source count: 3
    confidence: 0.6
    value label: heme biosynthetic process
  P682:
    value: Q1814528
    source count: 1
    confidence: 0.2
    value label: aerobic dissimilation
  P702:
    value: Q17909085
    source count: 1
    confidence: 0.2
    value label: COX10

value: Q15978631
source count: 1
confidence: 0.2
value label: Homo sapiens

value: ENSP00000261643
source count: 1
confidence: 0.2

value: ENSP00000397750
source count: 1
confidence: 0.2

value: ENSP00000462190
source count: 1
confidence: 0.2

value: ENSP00000462512
source count: 1
confidence: 0.2

value: ENSP00000499396
source count: 1
confidence: 0.2

source: GOA
stated in qid: Q28018111
retrieved: 2019-04-08

source: Isolation of a human cDNA for heme A:farnesyltransferase by functional complementation of a yeast cox10 mutant
stated in qid: Q24319047
retrieved: 2019-04-08

source: Mutations in COX10 result in a defect in mitochondrial heme A biosynthesis and account for multiple, early-onset clinical phenotypes associated with isolated COX deficiency
stated in qid: Q24317097
retrieved: 2019-04-08

source: Cytochrome c oxidase subassemblies in fibroblast cultures from patients carrying mutations in COX10, SCO1, or SURF1
stated in qid: Q24299371
retrieved: 2019-04-08

source: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
stated in qid: Q34211397
retrieved: 2019-04-08

source: A mutation in the human heme A:farnesyltransferase gene (COX10 ) causes cytochrome c oxidase deficiency
stated in qid: Q22253915
retrieved: 2018-03-27

source: A mutation in the human heme A:farnesyltransferase gene (COX10 ) causes cytochrome c oxidase deficiency
stated in qid: Q22253915
retrieved: 2019-04-08

source: InterPro Release 71.0
stated in qid: Q58943792

source: UniProt
stated in qid: Q905695
retrieved: 2019-11-13

source: Q20641742
stated in qid: Q20641742
retrieved: 2020-05-30

source: Ensembl Release 99
stated in qid: Q83867711

wikidata id: Q21100866
domain: protein
level: standard
html url: https://4ort.xyz/entity/cytochrome-c-oxidase-assembly-factor-heme-a-farnesyltransferase-cox10
markdown url: https://4ort.xyz/entity/cytochrome-c-oxidase-assembly-factor-heme-a-farnesyltransferase-cox10.md
facts url summary: https://4ort.xyz/entity/cytochrome-c-oxidase-assembly-factor-heme-a-farnesyltransferase-cox10/facts.json
facts url standard: https://4ort.xyz/entity/cytochrome-c-oxidase-assembly-factor-heme-a-farnesyltransferase-cox10/facts.json
facts url full: https://4ort.xyz/entity/cytochrome-c-oxidase-assembly-factor-heme-a-farnesyltransferase-cox10/facts.json
data source: Wikidata (CC0 / public domain)
license: https://creativecommons.org/publicdomain/zero/1.0/
api version: v1
served at: 2026-08-04T23:06:37.919673Z
entity updated at: 2026-05-03T18:28:36.114423+00:00Z
entity created at: 2026-05-03T15:25:56.647217+00:00Z