# Cytochrome b-245 alpha chain

> mammalian protein found in Rattus norvegicus

**Wikidata**: [Q28561435](https://www.wikidata.org/wiki/Q28561435)  
**Source**: https://4ort.xyz/entity/cytochrome-b-245-alpha-chain-q28561435


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q62737)
3. Q20641742
4. [Direct interaction of the novel Nox proteins with p22phox is required for the formation of a functionally active NADPH oxidase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62737)
5. [Poldip2, a novel regulator of Nox4 and cytoskeletal integrity in vascular smooth muscle cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62737)
6. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62737)
7. [p22phox is a critical component of the superoxide-generating NADH/NADPH oxidase system and regulates angiotensin II-induced hypertrophy in vascular smooth muscle cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62737)
8. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62737)
9. [Subcellular localization of nicotinamide adenine dinucleotide phosphate oxidase subunits in neurons and astroglia of the rat medial nucleus tractus solitarius: relationship with tyrosine hydroxylase immunoreactive neurons](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62737)
10. [The role of NOX2 and "novel oxidases" in airway chemoreceptor O(2) sensing](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62737)
11. [Glutamine plays a role in superoxide production and the expression of p47phox, p22phox and gp91phox in rat neutrophils](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62737)
12. [Molecular characterization and localization of the NAD(P)H oxidase components gp91-phox and p22-phox in endothelial cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62737)
13. [Effects of various degrees of oxidative stress induced by intermittent hypoxia in rat myocardial tissues](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62737)
14. [Nitric oxide synthase and NAD(P)H oxidase modulate coronary endothelial cell growth](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62737)
15. [p22phox in the macula densa regulates single nephron GFR during angiotensin II infusion in rats](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62737)
16. [Effect of danzhi jiangtang capsule combined exercise on the protein expression of NADPH oxidase p22phox in pancreatic tissues of diabetic rats](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62737)
17. [High dietary fat induces NADPH oxidase-associated oxidative stress and inflammation in rat cerebral cortex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62737)
18. [p22phox-derived superoxide mediates enhanced proliferative capacity of diabetic vascular smooth muscle cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62737)
19. [Homocysteine enhances TIMP-1 expression and cell proliferation associated with NADH oxidase in rat mesangial cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62737)
20. [RNA silencing in vivo reveals role of p22phox in rat angiotensin slow pressor response](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62737)
21. [Increased superoxide anion production by interleukin-1beta impairs nitric oxide-mediated relaxation in resistance arteries](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62737)
22. [Synergistic effect of mechanical stretch and angiotensin II on superoxide production via NADPH oxidase in vascular smooth muscle cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62737)
23. [Inhibition of superoxide anion generation by CHS-111 via blockade of the p21-activated kinase, protein kinase B/Akt and protein kinase C signaling pathways in rat neutrophils](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62737)
24. [High glucose mediates pro-oxidant and antioxidant enzyme activities in coronary endothelial cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62737)
25. [Rosiglitazone prevents high glucose-induced vascular endothelial growth factor and collagen IV expression in cultured mesangial cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62737)
26. [Tumour necrosis factor α activates a p22phox-based NADH oxidase in vascular smooth muscle](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62737)
27. [NADPH oxidase mediates radiation-induced oxidative stress in rat brain microvascular endothelial cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62737)
28. [Regulation of hypothalamic renin-angiotensin system and oxidative stress by aldosterone](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62737)
29. [Coronary microvascular endothelial cell growth regulates expression of the gene encoding p22-phox](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q62737)
30. ensembl Release 106