# Cystinosin, lysosomal cystine transporter

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21154758](https://www.wikidata.org/wiki/Q21154758)  
**Source**: https://4ort.xyz/entity/cystinosin-lysosomal-cystine-transporter-q21154758


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/O60931)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=O60931&geneProductId=UniProtKB:O60931)
5. [A novel gene encoding an integral membrane protein is mutated in nephropathic cystinosis](http://www.ebi.ac.uk/QuickGO/annotations?protein=O60931&geneProductId=UniProtKB:O60931)
6. [Molecular pathogenesis of cystinosis: effect of CTNS mutations on the transport activity and subcellular localization of cystinosin](http://www.ebi.ac.uk/QuickGO/annotations?protein=O60931&geneProductId=UniProtKB:O60931)
7. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60931)
8. [A novel gene encoding an integral membrane protein is mutated in nephropathic cystinosis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60931)
9. [Molecular pathogenesis of cystinosis: effect of CTNS mutations on the transport activity and subcellular localization of cystinosin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60931)
10. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60931)
11. [The targeting of cystinosin to the lysosomal membrane requires a tyrosine-based signal and a novel sorting motif](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60931)
12. [Immunolocalization of cystinosin, the protein defective in cystinosis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60931)
13. [Expression of CTNS alleles: subcellular localization and aminoglycoside correction in vitro](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60931)
14. [Identification and subcellular localization of a new cystinosin isoform](http://www.ebi.ac.uk/QuickGO/annotations?protein=O60931&geneProductId=UniProtKB:O60931)
15. [Large-scale proteomics and phosphoproteomics of urinary exosomes](http://www.ebi.ac.uk/QuickGO/annotations?protein=O60931&geneProductId=UniProtKB:O60931)
16. [The targeting of cystinosin to the lysosomal membrane requires a tyrosine-based signal and a novel sorting motif](http://www.ebi.ac.uk/QuickGO/annotations?protein=O60931&geneProductId=UniProtKB:O60931)
17. [Integral and associated lysosomal membrane proteins](http://www.ebi.ac.uk/QuickGO/annotations?protein=O60931&geneProductId=UniProtKB:O60931)
18. [Integral and associated lysosomal membrane proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60931)
19. [Large-scale proteomics and phosphoproteomics of urinary exosomes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60931)
20. [Non-verbal deficits in young children with a genetic metabolic disorder: WPPSI-III performance in cystinosis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60931)
21. [Altered status of glutathione and its metabolites in cystinotic cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60931)
22. [Decreased intracellular ATP content and intact mitochondrial energy generating capacity in human cystinotic fibroblasts](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60931)
23. [Cystine transport is defective in isolated leukocyte lysosomes from patients with cystinosis](http://www.ebi.ac.uk/QuickGO/annotations?protein=O60931&geneProductId=UniProtKB:O60931)
24. [Cystine transport is defective in isolated leukocyte lysosomes from patients with cystinosis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60931)
25. Ensembl Release 99
26. Transporter Classification database