# Cystathionine beta-synthase

> mammalian protein found in Homo sapiens

**Wikidata**: [Q5201183](https://www.wikidata.org/wiki/Q5201183)  
**Wikipedia**: [English](https://en.wikipedia.org/wiki/Cystathionine_beta_synthase)  
**Source**: https://4ort.xyz/entity/cystathionine-beta-synthase


## References

1. UniProt
2. IUPHAR/BPS Guide to PHARMACOLOGY
3. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P35520)
4. Q20641742
5. Freebase Data Dumps. 2013
6. [NO* binds human cystathionine β-synthase quickly and tightly](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35520)
7. [Structure of human cystathionine beta-synthase: a unique pyridoxal 5'-phosphate-dependent heme protein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35520)
8. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P35520&geneProductId=UniProtKB:P35520)
9. [Characterization of two pathogenic mutations in cystathionine beta-synthase: different intracellular locations for wild-type and mutant proteins](http://www.ebi.ac.uk/QuickGO/annotations?protein=P35520&geneProductId=UniProtKB:P35520)
10. [Kinetic characterization of recombinant human cystathionine beta-synthase purified from E. coli](http://www.ebi.ac.uk/QuickGO/annotations?protein=P35520&geneProductId=UniProtKB:P35520)
11. [Transsulfuration depends on heme in addition to pyridoxal 5'-phosphate. Cystathionine beta-synthase is a heme protein](http://www.ebi.ac.uk/QuickGO/annotations?protein=P35520&geneProductId=UniProtKB:P35520)
12. [Modulation of cystathionine beta-synthase activity by the Arg-51 and Arg-224 mutations](http://www.ebi.ac.uk/QuickGO/annotations?protein=P35520&geneProductId=UniProtKB:P35520)
13. [Human cystathionine β-synthase (CBS) contains two classes of binding sites for S-adenosylmethionine (SAM): complex regulation of CBS activity and stability by SAM](http://www.ebi.ac.uk/QuickGO/annotations?protein=P35520&geneProductId=UniProtKB:P35520)
14. [Nitrite reductase activity and inhibition of H₂S biogenesis by human cystathionine ß-synthase](http://www.ebi.ac.uk/QuickGO/annotations?protein=P35520&geneProductId=UniProtKB:P35520)
15. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35520)
16. [Nitrite reductase activity and inhibition of H₂S biogenesis by human cystathionine ß-synthase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35520)
17. [Human cystathionine beta-synthase is a target for sumoylation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35520)
18. [A proteome-scale map of the human interactome network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35520)
19. [NO* binds human cystathionine β-synthase quickly and tightly](http://www.ebi.ac.uk/QuickGO/annotations?protein=P35520&geneProductId=UniProtKB:P35520)
20. [Novel associations of CPS1, MUT, NOX4, and DPEP1 with plasma homocysteine in a healthy population: a genome-wide evaluation of 13 974 participants in the Women's Genome Health Study](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35520)
21. [Human cystathionine β-synthase (CBS) contains two classes of binding sites for S-adenosylmethionine (SAM): complex regulation of CBS activity and stability by SAM](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35520)
22. [A directed protein interaction network for investigating intracellular signal transduction](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35520)
23. [Shifted Transversal Design smart-pooling for high coverage interactome mapping](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35520)
24. [Towards a proteome-scale map of the human protein–protein interaction network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35520)
25. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35520)
26. [Modulation of cystathionine beta-synthase activity by the Arg-51 and Arg-224 mutations](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35520)
27. [Transsulfuration depends on heme in addition to pyridoxal 5'-phosphate. Cystathionine beta-synthase is a heme protein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35520)
28. [Kinetic characterization of recombinant human cystathionine beta-synthase purified from E. coli](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35520)
29. [Characterization of two pathogenic mutations in cystathionine beta-synthase: different intracellular locations for wild-type and mutant proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35520)
30. [Cell array-based intracellular localization screening reveals novel functional features of human chromosome 21 proteins](http://www.ebi.ac.uk/QuickGO/annotations?protein=P35520&geneProductId=UniProtKB:P35520)
31. [Cell array-based intracellular localization screening reveals novel functional features of human chromosome 21 proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35520)
32. [Homocysteine contribution to DNA damage in cystathionine β-synthase-deficient patients](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35520)
33. [Production of the neuromodulator H2S by cystathionine beta-synthase via the condensation of cysteine and homocysteine](http://www.ebi.ac.uk/QuickGO/annotations?protein=P35520&geneProductId=UniProtKB:P35520)
34. [Novel associations of CPS1, MUT, NOX4, and DPEP1 with plasma homocysteine in a healthy population: a genome-wide evaluation of 13 974 participants in the Women's Genome Health Study](http://www.ebi.ac.uk/QuickGO/annotations?protein=P35520&geneProductId=UniProtKB:P35520)
35. [Production of the neuromodulator H2S by cystathionine beta-synthase via the condensation of cysteine and homocysteine](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35520)
36. Ensembl Release 99
37. UMLS 2023
38. [OpenAlex](https://docs.openalex.org/download-snapshot/snapshot-data-format)