# Cyclin E1

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21100448](https://www.wikidata.org/wiki/Q21100448)  
**Source**: https://4ort.xyz/entity/cyclin-e1-q21100448


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P24864)
3. Q20641742
4. [Negative modulation of androgen receptor transcriptional activity by Daxx](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24864)
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24864)
6. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P24864&geneProductId=UniProtKB:P24864)
7. [NIRF constitutes a nodal point in the cell cycle network and is a candidate tumor suppressor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24864)
8. [Inhibitor of cyclin-dependent kinase (CDK) interacting with cyclin A1 (INCA1) regulates proliferation and is repressed by oncogenic signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24864)
9. [Structure of a Fbw7-Skp1-cyclin E complex: multisite-phosphorylated substrate recognition by SCF ubiquitin ligases](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24864)
10. [Cyclin E associates with BAF155 and BRG1, components of the mammalian SWI-SNF complex, and alters the ability of BRG1 to induce growth arrest](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24864)
11. [Foxp3 Protein Stability Is Regulated by Cyclin-dependent Kinase 2*](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24864)
12. [The protein interaction landscape of the human CMGC kinase group](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24864)
13. [Toward an understanding of the protein interaction network of the human liver](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24864)
14. [p27 phosphorylation by Src regulates inhibition of cyclin E-Cdk2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24864)
15. [ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24864)
16. [Regulation of the transcription factor FOXM1c by Cyclin E/CDK2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24864)
17. [G1/S Cyclins interact with regulatory subunit of PKA via A-kinase anchoring protein, AKAP95](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24864)
18. [Polycomb protein SCML2 regulates the cell cycle by binding and modulating CDK/CYCLIN/p21 complexes.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24864)
19. [HTLV-I p30 inhibits multiple S phase entry checkpoints, decreases cyclin E-CDK2 interactions and delays cell cycle progression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24864)
20. [Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24864)
21. [Cyclin-binding motifs are essential for the function of p21CIP1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24864)
22. [Integrative analysis of kinase networks in TRAIL-induced apoptosis provides a source of potential targets for combination therapy](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24864)
23. [Specificity of cyclin E-Cdk2, TFIIB, and E1A interactions with a common domain of the p300 coactivator](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24864)
24. [Cyclin E2, a novel human G1 cyclin and activating partner of CDK2 and CDK3, is induced by viral oncoproteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24864)
25. [Using an in Situ Proximity Ligation Assay to Systematically Profile Endogenous Protein–Protein Interactions in a Pathway Network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24864)
26. [RSK1 drives p27Kip1 phosphorylation at T198 to promote RhoA inhibition and increase cell motility](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24864)
27. [Increased p21 expression and complex formation with cyclin E/CDK2 in retinoid-induced pre-B lymphoma cell apoptosis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24864)
28. [Cdk-inhibitory activity and stability of p27Kip1 are directly regulated by oncogenic tyrosine kinases](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24864)
29. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24864)
30. [Mtd/Bok takes a swing: proapoptotic Mtd/Bok regulates trophoblast cell proliferation during human placental development and in preeclampsia](http://www.ebi.ac.uk/QuickGO/annotations?protein=P24864&geneProductId=UniProtKB:P24864)
31. [The bromodomain protein Brd4 is a positive regulatory component of P-TEFb and stimulates RNA polymerase II-dependent transcription](http://www.ebi.ac.uk/QuickGO/annotations?protein=P24864&geneProductId=UniProtKB:P24864)
32. [Mtd/Bok takes a swing: proapoptotic Mtd/Bok regulates trophoblast cell proliferation during human placental development and in preeclampsia](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24864)
33. [The bromodomain protein Brd4 is a positive regulatory component of P-TEFb and stimulates RNA polymerase II-dependent transcription](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24864)
34. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?protein=P24864&geneProductId=UniProtKB:P24864)
35. [A novel endogenous human CaMKII inhibitory protein suppresses tumor growth by inducing cell cycle arrest via p27 stabilization](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24864)
36. [Cullin-3 targets cyclin E for ubiquitination and controls S phase in mammalian cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24864)
37. [Alternative splicing of human cyclin E](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24864)
38. [MicroRNA-30c-2-3p negatively regulates NF-κB signaling and cell cycle progression through downregulation of TRADD and CCNE1 in breast cancer](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24864)
39. Ensembl Release 99