# Cyclin-dependent kinase inhibitor 1B

> mammalian protein found in Mus musculus

**Wikidata**: [Q21495041](https://www.wikidata.org/wiki/Q21495041)  
**Source**: https://4ort.xyz/entity/cyclin-dependent-kinase-inhibitor-1b-q21495041


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P46414)
3. Q20641742
4. [Lysine 269 is essential for cyclin D1 ubiquitylation by the SCF(Fbx4/alphaB-crystallin) ligase and subsequent proteasome-dependent degradation](http://www.ebi.ac.uk/QuickGO/annotations?protein=P46414&geneProductId=UniProtKB:P46414)
5. [Redistribution of the CDK inhibitor p27 between different cyclin.CDK complexes in the mouse fibroblast cell cycle and in cells arrested with lovastatin or ultraviolet irradiation](http://www.ebi.ac.uk/QuickGO/annotations?protein=P46414&geneProductId=UniProtKB:P46414)
6. [Cul4A targets p27 for degradation and regulates proliferation, cell cycle exit, and differentiation during erythropoiesis](http://www.ebi.ac.uk/QuickGO/annotations?protein=P46414&geneProductId=UniProtKB:P46414)
7. [p27, a novel inhibitor of G1 cyclin-Cdk protein kinase activity, is related to p21](http://www.ebi.ac.uk/QuickGO/annotations?protein=P46414&geneProductId=UniProtKB:P46414)
8. [p27(Kip1)-stathmin interaction influences sarcoma cell migration and invasion](http://www.ebi.ac.uk/QuickGO/annotations?protein=P46414&geneProductId=UniProtKB:P46414)
9. [The cell cycle regulator p27Kip1 interacts with MCM7, a DNA replication licensing factor, to inhibit initiation of DNA replication](http://www.ebi.ac.uk/QuickGO/annotations?protein=P46414&geneProductId=UniProtKB:P46414)
10. [Common and specific roles of the related CDK inhibitors p27 and p57 revealed by a knock-in mouse model](http://www.ebi.ac.uk/QuickGO/annotations?protein=P46414&geneProductId=UniProtKB:P46414)
11. [Cyclin D1-dependent kinase activity in murine development and mammary tumorigenesis](http://www.ebi.ac.uk/QuickGO/annotations?protein=P46414&geneProductId=UniProtKB:P46414)
12. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P46414&geneProductId=UniProtKB:P46414)
13. [Cyclin D-cdk4 activity modulates the subnuclear localization and interaction of MEF2 with SRC-family coactivators during skeletal muscle differentiation](http://www.ebi.ac.uk/QuickGO/annotations?protein=P46414&geneProductId=UniProtKB:P46414)
14. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?protein=P46414&geneProductId=UniProtKB:P46414)
15. [Cooperative functions of Hes/Hey genes in auditory hair cell and supporting cell development](http://www.ebi.ac.uk/QuickGO/annotations?protein=P46414&geneProductId=UniProtKB:P46414)
16. [Transcription factor KLF7 is important for neuronal morphogenesis in selected regions of the nervous system](http://www.ebi.ac.uk/QuickGO/annotations?protein=P46414&geneProductId=UniProtKB:P46414)
17. [Menin regulates pancreatic islet growth by promoting histone methylation and expression of genes encoding p27Kip1 and p18INK4c](http://www.ebi.ac.uk/QuickGO/annotations?protein=P46414&geneProductId=UniProtKB:P46414)
18. [Notch inhibition induces mitotically generated hair cells in mammalian cochleae via activating the Wnt pathway](http://www.ebi.ac.uk/QuickGO/annotations?protein=P46414&geneProductId=UniProtKB:P46414)
19. [The small GTPase Rac1 regulates auditory hair cell morphogenesis](http://www.ebi.ac.uk/QuickGO/annotations?protein=P46414&geneProductId=UniProtKB:P46414)
20. [A functional link between Wnt signaling and SKP2-independent p27 turnover in mammary tumors](http://www.ebi.ac.uk/QuickGO/annotations?protein=P46414&geneProductId=UniProtKB:P46414)
21. [Enhanced cardiomyocyte DNA synthesis during myocardial hypertrophy in mice expressing a modified TSC2 transgene](http://www.ebi.ac.uk/QuickGO/annotations?protein=P46414&geneProductId=UniProtKB:P46414)
22. [Altered prostatic epithelial proliferation and apoptosis, prostatic development, and serum testosterone in mice lacking cyclin-dependent kinase inhibitors](http://www.ebi.ac.uk/QuickGO/annotations?protein=P46414&geneProductId=UniProtKB:P46414)
23. [p27(Kip1) links cell proliferation to morphogenesis in the developing organ of Corti](http://www.ebi.ac.uk/QuickGO/annotations?protein=P46414&geneProductId=UniProtKB:P46414)
24. [Epileptogenesis and reduced inward rectifier potassium current in tuberous sclerosis complex-1-deficient astrocytes](http://www.ebi.ac.uk/QuickGO/annotations?protein=P46414&geneProductId=UniProtKB:P46414)
25. [The Cdk inhibitor p21 is required for necrosis, but it inhibits apoptosis following toxin-induced liver injury](http://www.ebi.ac.uk/QuickGO/annotations?protein=P46414&geneProductId=UniProtKB:P46414)
26. [Cell cycle regulation during mouse olfactory neurogenesis](http://www.ebi.ac.uk/QuickGO/annotations?protein=P46414&geneProductId=UniProtKB:P46414)
27. [Cooperation between the Cdk inhibitors p27(KIP1) and p57(KIP2) in the control of tissue growth and development](http://www.ebi.ac.uk/QuickGO/annotations?protein=P46414&geneProductId=UniProtKB:P46414)
28. ensembl Release 106