# Cyclin-dependent kinase inhibitor 1A (P21)

> mammalian protein found in Mus musculus

**Wikidata**: [Q14902457](https://www.wikidata.org/wiki/Q14902457)  
**Source**: https://4ort.xyz/entity/cyclin-dependent-kinase-inhibitor-1a-p21-


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P39689)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P39689&geneProductId=UniProtKB:P39689)
5. [Cyclin D-cdk4 activity modulates the subnuclear localization and interaction of MEF2 with SRC-family coactivators during skeletal muscle differentiation](http://www.ebi.ac.uk/QuickGO/annotations?protein=P39689&geneProductId=UniProtKB:P39689)
6. [GADD45b and GADD45g are cdc2/cyclinB1 kinase inhibitors with a role in S and G2/M cell cycle checkpoints induced by genotoxic stress](http://www.ebi.ac.uk/QuickGO/annotations?protein=P39689&geneProductId=UniProtKB:P39689)
7. [A mouse model uncovers LKB1 as an UVB-induced DNA damage sensor mediating CDKN1A (p21WAF1/CIP1) degradation](http://www.ebi.ac.uk/QuickGO/annotations?protein=P39689&geneProductId=UniProtKB:P39689)
8. [Caspase-3 regulates cell cycle in B cells: a consequence of substrate specificity](http://www.ebi.ac.uk/QuickGO/annotations?protein=P39689&geneProductId=UniProtKB:P39689)
9. [Hsc70 regulates accumulation of cyclin D1 and cyclin D1-dependent protein kinase](http://www.ebi.ac.uk/QuickGO/annotations?protein=P39689&geneProductId=UniProtKB:P39689)
10. [Specific function of phosphoinositide 3-kinase beta in the control of DNA replication](http://www.ebi.ac.uk/QuickGO/annotations?protein=P39689&geneProductId=UniProtKB:P39689)
11. [Interaction of CR6 (GADD45gamma ) with proliferating cell nuclear antigen impedes negative growth control](http://www.ebi.ac.uk/QuickGO/annotations?protein=P39689&geneProductId=UniProtKB:P39689)
12. [Transcription factor KLF7 is important for neuronal morphogenesis in selected regions of the nervous system](http://www.ebi.ac.uk/QuickGO/annotations?protein=P39689&geneProductId=UniProtKB:P39689)
13. [Pecam-1 is a modulator of stat family member phosphorylation and localization: lessons from a transgenic mouse](http://www.ebi.ac.uk/QuickGO/annotations?protein=P39689&geneProductId=UniProtKB:P39689)
14. [Cyclin-dependent kinase 8 mediates chemotherapy-induced tumor-promoting paracrine activities.](http://www.ebi.ac.uk/QuickGO/annotations?protein=P39689&geneProductId=UniProtKB:P39689)
15. [Integral role of Noxa in p53-mediated apoptotic response](http://www.ebi.ac.uk/QuickGO/annotations?protein=P39689&geneProductId=UniProtKB:P39689)
16. [The p21(Cip1) protein, a cyclin inhibitor, regulates the levels and the intracellular localization of CDC25A in mice regenerating livers](http://www.ebi.ac.uk/QuickGO/annotations?protein=P39689&geneProductId=UniProtKB:P39689)
17. [The Cdk inhibitor p21 is required for necrosis, but it inhibits apoptosis following toxin-induced liver injury](http://www.ebi.ac.uk/QuickGO/annotations?protein=P39689&geneProductId=UniProtKB:P39689)
18. [Translational Upregulation of an Individual p21Cip1 Transcript Variant by GCN2 Regulates Cell Proliferation and Survival under Nutrient Stress](http://www.ebi.ac.uk/QuickGO/annotations?protein=P39689&geneProductId=UniProtKB:P39689)
19. [Absence of p21 partially rescues Mdm4 loss and uncovers an antiproliferative effect of Mdm4 on cell growth](http://www.ebi.ac.uk/QuickGO/annotations?protein=P39689&geneProductId=UniProtKB:P39689)
20. [DNA damage-induced activation of p53 by the checkpoint kinase Chk2](http://www.ebi.ac.uk/QuickGO/annotations?protein=P39689&geneProductId=UniProtKB:P39689)
21. ensembl Release 106