# Cyclin dependent kinase 9

> mammalian protein found in Homo sapiens

**Wikidata**: [Q5198256](https://www.wikidata.org/wiki/Q5198256)  
**Source**: https://4ort.xyz/entity/cyclin-dependent-kinase-9-q5198256


## References

1. UniProt
2. IUPHAR/BPS Guide to PHARMACOLOGY
3. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P50750)
4. Q20641742
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50750)
6. [PITALRE, a nuclear CDC2-related protein kinase that phosphorylates the retinoblastoma protein in vitro](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50750)
7. [7SK small nuclear RNA binds to and inhibits the activity of CDK9/cyclin T complexes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50750)
8. [Physical interaction between pRb and cdk9/cyclinT2 complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50750)
9. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P50750&geneProductId=UniProtKB:P50750)
10. [The bromodomain protein Brd4 is a positive regulatory component of P-TEFb and stimulates RNA polymerase II-dependent transcription](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50750)
11. [Transcriptional activity and substrate recognition of cyclin T2 from P-TEFb](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50750)
12. [Pkn is a novel partner of cyclin T2a in muscle differentiation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50750)
13. [Brd4 and JMJD6-associated anti-pause enhancers in regulation of transcriptional pause release](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50750)
14. [Identification of multiple cyclin subunits of human P-TEFb](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50750)
15. [MAQ1 and 7SK RNA interact with CDK9/cyclin T complexes in a transcription-dependent manner](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50750)
16. [BRCA1 cooperates with NUFIP and P-TEFb to activate transcription by RNA polymerase II](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50750)
17. [The structure of P-TEFb (CDK9/cyclin T1), its complex with flavopiridol and regulation by phosphorylation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50750)
18. [LARP7 is a stable component of the 7SK snRNP while P-TEFb, HEXIM1 and hnRNP A1 are reversibly associated](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50750)
19. [Acetylation of cyclin T1 regulates the equilibrium between active and inactive P-TEFb in cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50750)
20. [The CDK9 Tail Determines the Reaction Pathway of Positive Transcription Elongation Factor b](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50750)
21. [Protein Phosphatase-1 Activates CDK9 by Dephosphorylating Ser175](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50750)
22. [Quantitative analysis of HSP90-client interactions reveals principles of substrate recognition](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50750)
23. [Conserved P-TEFb-interacting domain of BRD4 inhibits HIV transcription](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50750)
24. [Nuclear CDKs drive Smad transcriptional activation and turnover in BMP and TGF-beta pathways](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50750)
25. [Implication of BRG1 and cdk9 in the STAT3-mediated activation of the p21waf1 gene](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50750)
26. [RNA helicase DDX21 coordinates transcription and ribosomal RNA processing](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50750)
27. [The La-related protein LARP7 is a component of the 7SK ribonucleoprotein and affects transcription of cellular and viral polymerase II genes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50750)
28. [Crystal structure of HIV-1 Tat complexed with human P-TEFb](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50750)
29. [Cyclin‐dependent kinase 9–cyclin K functions in the replication stress response](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50750)
30. [RNA-mediated displacement of an inhibitory snRNP complex activates transcription elongation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50750)
31. [A quantitative chaperone interaction network reveals the architecture of cellular protein homeostasis pathways](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50750)
32. [Global landscape of HIV-human protein complexes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50750)
33. [Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50750)
34. [The protein interaction landscape of the human CMGC kinase group](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50750)
35. [RNA polymerase II–associated factor 1 regulates the release and phosphorylation of paused RNA polymerase II](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50750)
36. [Perturbation of the mutated EGFR interactome identifies vulnerabilities and resistance mechanisms](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50750)
37. [Human mediator subunit MED26 functions as a docking site for transcription elongation factors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50750)
38. [Systematic Analysis of Human Protein Phosphatase Interactions and Dynamics.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50750)
39. [A higher-order complex containing AF4 and ENL family proteins with P-TEFb facilitates oncogenic and physiologic MLL-dependent transcription](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50750)
40. [Inhibition of P-TEFb (CDK9/Cyclin T) kinase and RNA polymerase II transcription by the coordinated actions of HEXIM1 and 7SK snRNA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50750)
41. [HEXIM2, a HEXIM1-related protein, regulates positive transcription elongation factor b through association with 7SK](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50750)
42. [Tat modifies the activity of CDK9 to phosphorylate serine 5 of the RNA polymerase II carboxyl-terminal domain during human immunodeficiency virus type 1 transcription](http://www.ebi.ac.uk/QuickGO/annotations?protein=P50750&geneProductId=UniProtKB:P50750)
43. [Activation of MyoD-dependent transcription by cdk9/cyclin T2](http://www.ebi.ac.uk/QuickGO/annotations?protein=P50750&geneProductId=UniProtKB:P50750)
44. [A Novel RNA Polymerase II C-terminal Domain Phosphatase That Preferentially Dephosphorylates Serine 5](http://www.ebi.ac.uk/QuickGO/annotations?protein=P50750&geneProductId=UniProtKB:P50750)
45. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50750)
46. [Tat modifies the activity of CDK9 to phosphorylate serine 5 of the RNA polymerase II carboxyl-terminal domain during human immunodeficiency virus type 1 transcription](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50750)
47. [Activation of MyoD-dependent transcription by cdk9/cyclin T2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50750)
48. [A Novel RNA Polymerase II C-terminal Domain Phosphatase That Preferentially Dephosphorylates Serine 5](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50750)
49. [Defining the membrane proteome of NK cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=P50750&geneProductId=UniProtKB:P50750)
50. [The little elongation complex regulates small nuclear RNA transcription](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50750)