# Cyclin-dependent kinase 2

> mammalian protein found in Mus musculus

**Wikidata**: [Q14911733](https://www.wikidata.org/wiki/Q14911733)  
**Source**: https://4ort.xyz/entity/cyclin-dependent-kinase-2-q14911733


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P97377)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P97377&geneProductId=UniProtKB:P97377)
5. [CDK6 kinase activity is required for thymocyte development](http://www.ebi.ac.uk/QuickGO/annotations?protein=P97377&geneProductId=UniProtKB:P97377)
6. [Deletion of Mnt leads to disrupted cell cycle control and tumorigenesis](http://www.ebi.ac.uk/QuickGO/annotations?protein=P97377&geneProductId=UniProtKB:P97377)
7. [Caspase-3 regulates cell cycle in B cells: a consequence of substrate specificity](http://www.ebi.ac.uk/QuickGO/annotations?protein=P97377&geneProductId=UniProtKB:P97377)
8. [GADD45b and GADD45g are cdc2/cyclinB1 kinase inhibitors with a role in S and G2/M cell cycle checkpoints induced by genotoxic stress](http://www.ebi.ac.uk/QuickGO/annotations?protein=P97377&geneProductId=UniProtKB:P97377)
9. [The transcriptional co-activator PCAF regulates cdk2 activity](http://www.ebi.ac.uk/QuickGO/annotations?protein=P97377&geneProductId=UniProtKB:P97377)
10. [Liver tumors escape negative control of proliferation via PI3K/Akt-mediated block of C/EBP alpha growth inhibitory activity](http://www.ebi.ac.uk/QuickGO/annotations?protein=P97377&geneProductId=UniProtKB:P97377)
11. [p27, a novel inhibitor of G1 cyclin-Cdk protein kinase activity, is related to p21](http://www.ebi.ac.uk/QuickGO/annotations?protein=P97377&geneProductId=UniProtKB:P97377)
12. [Cyclin A is redundant in fibroblasts but essential in hematopoietic and embryonic stem cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=P97377&geneProductId=UniProtKB:P97377)
13. [Genetic analysis of Ras signalling pathways in cell proliferation, migration and survival.](http://www.ebi.ac.uk/QuickGO/annotations?protein=P97377&geneProductId=UniProtKB:P97377)
14. [Heat shock protein 90 functions to stabilize and activate the testis-specific serine/threonine kinases, a family of kinases essential for male fertility](http://www.ebi.ac.uk/QuickGO/annotations?protein=P97377&geneProductId=UniProtKB:P97377)
15. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?protein=P97377&geneProductId=UniProtKB:P97377)
16. [C/EBPalpha regulates formation of S-phase-specific E2F-p107 complexes in livers of newborn mice](http://www.ebi.ac.uk/QuickGO/annotations?protein=P97377&geneProductId=UniProtKB:P97377)
17. [Mutation in mouse hei10, an e3 ubiquitin ligase, disrupts meiotic crossing over](http://www.ebi.ac.uk/QuickGO/annotations?protein=P97377&geneProductId=UniProtKB:P97377)
18. [Mammalian CNTD1 is critical for meiotic crossover maturation and deselection of excess precrossover sites](http://www.ebi.ac.uk/QuickGO/annotations?protein=P97377&geneProductId=UniProtKB:P97377)
19. [Novel INK4 proteins, p19 and p18, are specific inhibitors of the cyclin D-dependent kinases CDK4 and CDK6](http://www.ebi.ac.uk/QuickGO/annotations?protein=P97377&geneProductId=UniProtKB:P97377)
20. [Cyclin A2-CDK2 regulates embryonic gene activation in 1-cell mouse embryos](http://www.ebi.ac.uk/QuickGO/annotations?protein=P97377&geneProductId=UniProtKB:P97377)
21. [Epileptogenesis and reduced inward rectifier potassium current in tuberous sclerosis complex-1-deficient astrocytes](http://www.ebi.ac.uk/QuickGO/annotations?protein=P97377&geneProductId=UniProtKB:P97377)
22. [Ciz1 cooperates with cyclin-A-CDK2 to activate mammalian DNA replication in vitro](http://www.ebi.ac.uk/QuickGO/annotations?protein=P97377&geneProductId=UniProtKB:P97377)
23. [miR-29b represses intestinal mucosal growth by inhibiting translation of cyclin-dependent kinase 2](http://www.ebi.ac.uk/QuickGO/annotations?protein=P97377&geneProductId=UniProtKB:P97377)
24. [Regulation of the retinoblastoma protein-related p107 by G1 cyclin complexes](http://www.ebi.ac.uk/QuickGO/annotations?protein=P97377&geneProductId=UniProtKB:P97377)
25. ensembl Release 106