# Cyclin-dependent kinase 1

> mammalian protein found in Mus musculus

**Wikidata**: [Q15325394](https://www.wikidata.org/wiki/Q15325394)  
**Source**: https://4ort.xyz/entity/cyclin-dependent-kinase-1-q15325394


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P11440)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11440)
5. [HSP70-2 is required for CDC2 kinase activity in meiosis I of mouse spermatocytes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11440)
6. [DNA damage-induced G2/M checkpoint in SV40 large T antigen-immortalized embryonic fibroblast cells requires SHP-2 tyrosine phosphatase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11440)
7. [GADD45b and GADD45g are cdc2/cyclinB1 kinase inhibitors with a role in S and G2/M cell cycle checkpoints induced by genotoxic stress](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11440)
8. [Cyclin-dependent kinase-associated proteins Cks1 and Cks2 are essential during early embryogenesis and for cell cycle progression in somatic cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11440)
9. [Tex14, a Plk1-Regulated Protein, Is Required for Kinetochore-Microtubule Attachment and Regulation of the Spindle Assembly Checkpoint](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11440)
10. [RGC-32 increases p34CDC2 kinase activity and entry of aortic smooth muscle cells into S-phase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11440)
11. [Cdk1 interplays with Oct4 to repress differentiation of embryonic stem cells into trophectoderm](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11440)
12. [Cyclin A is redundant in fibroblasts but essential in hematopoietic and embryonic stem cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11440)
13. [Cdk1 is sufficient to drive the mammalian cell cycle](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11440)
14. [Polo-like kinase is required for synaptonemal complex disassembly and phosphorylation in mouse spermatocytes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11440)
15. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P11440&geneProductId=UniProtKB:P11440)
16. [Tex14, a Plk1-Regulated Protein, Is Required for Kinetochore-Microtubule Attachment and Regulation of the Spindle Assembly Checkpoint](http://www.ebi.ac.uk/QuickGO/annotations?protein=P11440&geneProductId=UniProtKB:P11440)
17. [Novel INK4 proteins, p19 and p18, are specific inhibitors of the cyclin D-dependent kinases CDK4 and CDK6](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11440)
18. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11440)
19. [The bromodomain protein Brd4 is a positive regulatory component of P-TEFb and stimulates RNA polymerase II-dependent transcription](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11440)
20. [Cyclin B1/Cdk1 Coordinates Mitochondrial Respiration for Cell-Cycle G2/M Progression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11440)
21. [Cyclin-dependent kinase-associated proteins Cks1 and Cks2 are essential during early embryogenesis and for cell cycle progression in somatic cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=P11440&geneProductId=UniProtKB:P11440)
22. [Mitochondrial degeneration and not apoptosis is the primary cause of embryonic lethality in ceramide transfer protein mutant mice](http://www.ebi.ac.uk/QuickGO/annotations?protein=P11440&geneProductId=UniProtKB:P11440)
23. [GADD45b and GADD45g are cdc2/cyclinB1 kinase inhibitors with a role in S and G2/M cell cycle checkpoints induced by genotoxic stress](http://www.ebi.ac.uk/QuickGO/annotations?protein=P11440&geneProductId=UniProtKB:P11440)
24. [Mitochondrial degeneration and not apoptosis is the primary cause of embryonic lethality in ceramide transfer protein mutant mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11440)
25. ensembl Release 106