# Cullin 4B

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21112921](https://www.wikidata.org/wiki/Q21112921)  
**Source**: https://4ort.xyz/entity/cullin-4b


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q13620)
3. Q20641742
4. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13620)
5. [Monoubiquitinated Histone H2A Destabilizes Photolesion-containing Nucleosomes with Concomitant Release of UV-damaged DNA-binding Protein E3 Ligase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13620)
6. [A family of diverse Cul4-Ddb1-interacting proteins includes Cdt2, which is required for S phase destruction of the replication factor Cdt1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13620)
7. [CUL4-DDB1 ubiquitin ligase interacts with multiple WD40-repeat proteins and regulates histone methylation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13620)
8. [COMMD1 (Copper Metabolism MURR1 Domain-containing Protein 1) Regulates Cullin RING Ligases by Preventing CAND1 (Cullin-associated Nedd8-dissociated Protein 1) Binding](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13620)
9. [UBXD7 binds multiple ubiquitin ligases and implicates p97 in HIF1alpha turnover](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13620)
10. [NEDD8 links cullin-RING ubiquitin ligase function to the p97 pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13620)
11. [A quantitative chaperone interaction network reveals the architecture of cellular protein homeostasis pathways](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13620)
12. [A human interactome in three quantitative dimensions organized by stoichiometries and abundances](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13620)
13. [Widespread macromolecular interaction perturbations in human genetic disorders](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13620)
14. [Structural Mechanism of Nuclear Transport Mediated by Importin β and Flexible Amphiphilic Proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13620)
15. [Quantitative analysis of HSP90-client interactions reveals principles of substrate recognition](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13620)
16. [TIP120A associates with cullins and modulates ubiquitin ligase activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13620)
17. [Aryl hydrocarbon receptor suppresses intestinal carcinogenesis in ApcMin/+ mice with natural ligands](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13620)
18. [CRL4B catalyzes H2AK119 monoubiquitination and coordinates with PRC2 to promote tumorigenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13620)
19. [Molecular architecture and assembly of the DDB1-CUL4A ubiquitin ligase machinery](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13620)
20. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13620)
21. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13620&geneProductId=UniProtKB:Q13620)
22. [Large-scale proteomics and phosphoproteomics of urinary exosomes](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13620&geneProductId=UniProtKB:Q13620)
23. [PCNA-dependent regulation of p21 ubiquitylation and degradation via the CRL4Cdt2 ubiquitin ligase complex](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13620&geneProductId=UniProtKB:Q13620)
24. [Monoubiquitinated Histone H2A Destabilizes Photolesion-containing Nucleosomes with Concomitant Release of UV-damaged DNA-binding Protein E3 Ligase](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13620&geneProductId=UniProtKB:Q13620)
25. [Selective ubiquitylation of p21 and Cdt1 by UBCH8 and UBE2G ubiquitin-conjugating enzymes via the CRL4Cdt2 ubiquitin ligase complex](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13620&geneProductId=UniProtKB:Q13620)
26. [A family of diverse Cul4-Ddb1-interacting proteins includes Cdt2, which is required for S phase destruction of the replication factor Cdt1](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13620&geneProductId=UniProtKB:Q13620)
27. [PCNA-dependent regulation of p21 ubiquitylation and degradation via the CRL4Cdt2 ubiquitin ligase complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13620)
28. [Selective ubiquitylation of p21 and Cdt1 by UBCH8 and UBE2G ubiquitin-conjugating enzymes via the CRL4Cdt2 ubiquitin ligase complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13620)
29. [Large-scale proteomics and phosphoproteomics of urinary exosomes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13620)
30. [cul-1 is required for cell cycle exit in C. elegans and identifies a novel gene family](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13620&geneProductId=UniProtKB:Q13620)
31. [FBXO44-Mediated Degradation of RGS2 Protein Uniquely Depends on a Cullin 4B/DDB1 Complex.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13620)
32. [Selective degradation of splicing factor CAPERα by anticancer sulfonamides](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13620)
33. [cul-1 is required for cell cycle exit in C. elegans and identifies a novel gene family](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13620)
34. ensembl Release 98