# crystallin alpha B

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21100907](https://www.wikidata.org/wiki/Q21100907)  
**Source**: https://4ort.xyz/entity/crystallin-alpha-b-q21100907


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P02511)
3. Q20641742
4. [Crystal structures of alpha-crystallin domain dimers of alphaB-crystallin and Hsp20](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02511)
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02511)
6. [Lenticular chaperones suppress the aggregation of the cataract-causing mutant T5P gamma C-crystallin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02511)
7. [αB-crystallin is a sensor for assembly intermediates and for the subunit topology of desmin intermediate filaments.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02511)
8. [Synergistic efficacy of LBH and alphaB-crystallin through inhibiting transcriptional activities of p53 and p21.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02511)
9. [Human alphaA- and alphaB-crystallins bind to Bax and Bcl-X(S) to sequester their translocation during staurosporine-induced apoptosis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02511)
10. [alphaB-crystallin competes with Alzheimer's disease beta-amyloid peptide for peptide-peptide interactions and induces oxidation of Abeta-Met35](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02511)
11. [Characterization of the Cardiac Overexpression of HSPB2 Reveals Mitochondrial and Myogenic Roles Supported by a Cardiac HspB2 Interactome.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02511)
12. [Binding determinants of the small heat shock protein, αB-crystallin: recognition of the 'IxI' motif](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02511)
13. [Preferential and Specific Binding of Human αB-Crystallin to a Cataract-Related Variant of γS-Crystallin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02511)
14. [The polydispersity of αB-crystallin is rationalized by an interconverting polyhedral architecture](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02511)
15. [The eye lens chaperone alpha-crystallin forms defined globular assemblies.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02511)
16. [Widespread macromolecular interaction perturbations in human genetic disorders](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02511)
17. [Protective role of the endoplasmic reticulum protein mitsugumin23 against ultraviolet C‐induced cell death](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02511)
18. [Temperature-dependent structural and functional properties of a mutant (F71L) αA-crystallin: Molecular basis for early onset of age-related cataract](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02511)
19. [Interactions of HSP22 (HSPB8) with HSP20, alphaB-crystallin, and HSPB3](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02511)
20. [Alteration of protein-protein interactions of congenital cataract crystallin mutants](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02511)
21. [Construction and characterization of a normalized yeast two-hybrid library derived from a human protein-coding clone collection](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02511)
22. [Detection of Protein-Protein Interactions among Lens Crystallins in a Mammalian Two-hybrid System Assay](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02511)
23. [Role of the C-terminal extensions of alpha-crystallins. Swapping the C-terminal extension of alpha-crystallin to alphaB-crystallin results in enhanced chaperone activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02511)
24. [N-terminal domain of  B-crystallin provides a conformational switch for multimerization and structural heterogeneity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02511)
25. [Solid-state NMR and SAXS studies provide a structural basis for the activation of αB-crystallin oligomers](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02511)
26. [Multiple molecular architectures of the eye lens chaperone  B-crystallin elucidated by a triple hybrid approach](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02511)
27. [Amyloid-β oligomers are sequestered by both intracellular and extracellular chaperones](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02511)
28. [HSPB7 is a SC35 speckle resident small heat shock protein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02511)
29. [Proteomic analysis of podocyte exosome-enriched fraction from normal human urine](http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P02511)
30. [In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine](http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P02511)
31. [Large-scale proteomics and phosphoproteomics of urinary exosomes](http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P02511)
32. [Large-scale proteomics and phosphoproteomics of urinary exosomes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02511)
33. [In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02511)
34. [A missense mutation in the alphaB-crystallin chaperone gene causes a desmin-related myopathy](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02511)
35. Ensembl Release 99
36. UMLS 2023