# crystallin alpha A

> mammalian protein found in Homo sapiens

**Wikidata**: [Q22676584](https://www.wikidata.org/wiki/Q22676584)  
**Source**: https://4ort.xyz/entity/crystallin-alpha-a-q22676584


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P02489)
3. Q20641742
4. [Cloning, expression, and chaperone-like activity of human alphaA-crystallin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02489)
5. [A novel mutation in AlphaA-crystallin (CRYAA) caused autosomal dominant congenital cataract in a large Chinese family](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02489)
6. [Human alphaA- and alphaB-crystallins bind to Bax and Bcl-X(S) to sequester their translocation during staurosporine-induced apoptosis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02489)
7. [Widespread macromolecular interaction perturbations in human genetic disorders](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02489)
8. [The eye lens chaperone alpha-crystallin forms defined globular assemblies.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02489)
9. [Temperature-dependent structural and functional properties of a mutant (F71L) αA-crystallin: Molecular basis for early onset of age-related cataract](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02489)
10. [A proteome-scale map of the human interactome network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02489)
11. [Alteration of protein-protein interactions of congenital cataract crystallin mutants](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02489)
12. [Detection of Protein-Protein Interactions among Lens Crystallins in a Mammalian Two-hybrid System Assay](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02489)
13. [Binding determinants of the small heat shock protein, αB-crystallin: recognition of the 'IxI' motif](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02489)
14. [The polydispersity of αB-crystallin is rationalized by an interconverting polyhedral architecture](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02489)
15. [Role of the C-terminal extensions of alpha-crystallins. Swapping the C-terminal extension of alpha-crystallin to alphaB-crystallin results in enhanced chaperone activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02489)
16. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02489)
17. [HSPB7 is a SC35 speckle resident small heat shock protein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02489)
18. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A0A140G945)
19. [Cell death triggered by a novel mutation in the alphaA-crystallin gene underlies autosomal dominant cataract linked to chromosome 21q](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02489)
20. [Lenticular chaperones suppress the aggregation of the cataract-causing mutant T5P gamma C-crystallin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02489)
21. [Crystallin gene mutations in Indian families with inherited pediatric cataract](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02489)
22. [Autosomal dominant congenital cataract associated with a missense mutation in the human alpha crystallin gene CRYAA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02489)
23. Ensembl Release 99
24. UMLS 2023