# Cryptochrome 1 (photolyase-like)

> mammalian protein found in Mus musculus

**Wikidata**: [Q14866013](https://www.wikidata.org/wiki/Q14866013)  
**Source**: https://4ort.xyz/entity/cryptochrome-1-photolyase-like-


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P97784)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P97784&geneProductId=UniProtKB:P97784)
5. [Biochemical analysis of the canonical model for the mammalian circadian clock](http://www.ebi.ac.uk/QuickGO/annotations?protein=P97784&geneProductId=UniProtKB:P97784)
6. [Circadian and light-induced transcription of clock gene Per1 depends on histone acetylation and deacetylation](http://www.ebi.ac.uk/QuickGO/annotations?protein=P97784&geneProductId=UniProtKB:P97784)
7. [Phosphorylation of the cryptochrome 1 C-terminal tail regulates circadian period length](http://www.ebi.ac.uk/QuickGO/annotations?protein=P97784&geneProductId=UniProtKB:P97784)
8. [Role of Type II Protein Arginine Methyltransferase 5 in the Regulation of Circadian Per1 Gene](http://www.ebi.ac.uk/QuickGO/annotations?protein=P97784&geneProductId=UniProtKB:P97784)
9. [Temporal orchestration of repressive chromatin modifiers by circadian clock Period complexes](http://www.ebi.ac.uk/QuickGO/annotations?protein=P97784&geneProductId=UniProtKB:P97784)
10. [Competing E3 ubiquitin ligases govern circadian periodicity by degradation of CRY in nucleus and cytoplasm](http://www.ebi.ac.uk/QuickGO/annotations?protein=P97784&geneProductId=UniProtKB:P97784)
11. [FBXL21 Regulates Oscillation of the Circadian Clock through Ubiquitination and Stabilization of Cryptochromes](http://www.ebi.ac.uk/QuickGO/annotations?protein=P97784&geneProductId=UniProtKB:P97784)
12. [Nucleocytoplasmic shuttling and mCRY-dependent inhibition of ubiquitylation of the mPER2 clock protein](http://www.ebi.ac.uk/QuickGO/annotations?protein=P97784&geneProductId=UniProtKB:P97784)
13. [The polycomb group protein EZH2 is required for mammalian circadian clock function](http://www.ebi.ac.uk/QuickGO/annotations?protein=P97784&geneProductId=UniProtKB:P97784)
14. [Modulation of ATR-mediated DNA damage checkpoint response by cryptochrome 1](http://www.ebi.ac.uk/QuickGO/annotations?protein=P97784&geneProductId=UniProtKB:P97784)
15. [The mammalian clock component PERIOD2 coordinates circadian output by interaction with nuclear receptors](http://www.ebi.ac.uk/QuickGO/annotations?protein=P97784&geneProductId=UniProtKB:P97784)
16. [SIRT1 regulates circadian clock gene expression through PER2 deacetylation](http://www.ebi.ac.uk/QuickGO/annotations?protein=P97784&geneProductId=UniProtKB:P97784)
17. [Mammalian TIMELESS Is Involved in Period Determination and DNA Damage-Dependent Phase Advancing of the Circadian Clock](http://www.ebi.ac.uk/QuickGO/annotations?protein=P97784&geneProductId=UniProtKB:P97784)
18. [Molecular characterization of Mybbp1a as a co-repressor on the Period2 promoter](http://www.ebi.ac.uk/QuickGO/annotations?protein=P97784&geneProductId=UniProtKB:P97784)
19. [Circadian mutant Overtime reveals F-box protein FBXL3 regulation of cryptochrome and period gene expression](http://www.ebi.ac.uk/QuickGO/annotations?protein=P97784&geneProductId=UniProtKB:P97784)
20. [Direct association between mouse PERIOD and CKIepsilon is critical for a functioning circadian clock](http://www.ebi.ac.uk/QuickGO/annotations?protein=P97784&geneProductId=UniProtKB:P97784)
21. [Machine Learning Helps Identify CHRONO as a Circadian Clock Component](http://www.ebi.ac.uk/QuickGO/annotations?protein=P97784&geneProductId=UniProtKB:P97784)
22. [The BMAL1 C terminus regulates the circadian transcription feedback loop.](http://www.ebi.ac.uk/QuickGO/annotations?protein=P97784&geneProductId=UniProtKB:P97784)
23. [Dynamic circadian protein-protein interaction networks predict temporal organization of cellular functions](http://www.ebi.ac.uk/QuickGO/annotations?protein=P97784&geneProductId=UniProtKB:P97784)
24. [CRY Drives Cyclic CK2-Mediated BMAL1 Phosphorylation to Control the Mammalian Circadian Clock](http://www.ebi.ac.uk/QuickGO/annotations?protein=P97784&geneProductId=UniProtKB:P97784)
25. [Cryptochrome 1 regulates the circadian clock through dynamic interactions with the BMAL1 C terminus](http://www.ebi.ac.uk/QuickGO/annotations?protein=P97784&geneProductId=UniProtKB:P97784)
26. [CAVIN‐3 regulates circadian period length and PER:CRY protein abundance and interactions](http://www.ebi.ac.uk/QuickGO/annotations?protein=P97784&geneProductId=UniProtKB:P97784)
27. [Cryptochromes mediate rhythmic repression of the glucocorticoid receptor](http://www.ebi.ac.uk/QuickGO/annotations?protein=P97784&geneProductId=UniProtKB:P97784)
28. [CLOCK-mediated acetylation of BMAL1 controls circadian function](http://www.ebi.ac.uk/QuickGO/annotations?protein=P97784&geneProductId=UniProtKB:P97784)
29. [Interaction of Circadian Clock Proteins CRY1 and PER2 Is Modulated by Zinc Binding and Disulfide Bond Formation](http://www.ebi.ac.uk/QuickGO/annotations?protein=P97784&geneProductId=UniProtKB:P97784)
30. [Poly(ADP-ribose) polymerase 1 participates in the phase entrainment of circadian clocks to feeding](http://www.ebi.ac.uk/QuickGO/annotations?protein=P97784&geneProductId=UniProtKB:P97784)
31. [Interaction of circadian clock proteins PER2 and CRY with BMAL1 and CLOCK](http://www.ebi.ac.uk/QuickGO/annotations?protein=P97784&geneProductId=UniProtKB:P97784)
32. [Characterization of photolyase/blue-light receptor homologs in mouse and human cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=P97784&geneProductId=UniProtKB:P97784)
33. [AMPK regulates the circadian clock by cryptochrome phosphorylation and degradation](http://www.ebi.ac.uk/QuickGO/annotations?protein=P97784&geneProductId=UniProtKB:P97784)
34. [A mitochondrial protein compendium elucidates complex I disease biology](http://www.ebi.ac.uk/QuickGO/annotations?protein=P97784&geneProductId=UniProtKB:P97784)
35. [Large-scale identification of mammalian proteins localized to nuclear sub-compartments](http://www.ebi.ac.uk/QuickGO/annotations?protein=P97784&geneProductId=UniProtKB:P97784)
36. [The orphan nuclear receptor REV-ERBalpha controls circadian transcription within the positive limb of the mammalian circadian oscillator](http://www.ebi.ac.uk/QuickGO/annotations?protein=P97784&geneProductId=UniProtKB:P97784)
37. [Functional and structural analyses of cryptochrome. Vertebrate CRY regions responsible for interaction with the CLOCK:BMAL1 heterodimer and its nuclear localization](http://www.ebi.ac.uk/QuickGO/annotations?protein=P97784&geneProductId=UniProtKB:P97784)
38. [Cryptochrome mediates circadian regulation of cAMP signaling and hepatic gluconeogenesis](http://www.ebi.ac.uk/QuickGO/annotations?protein=P97784&geneProductId=UniProtKB:P97784)
39. [Modulation of glucocorticoid receptor induction properties by core circadian clock proteins](http://www.ebi.ac.uk/QuickGO/annotations?protein=P97784&geneProductId=UniProtKB:P97784)
40. [CIPC is a mammalian circadian clock protein without invertebrate homologues](http://www.ebi.ac.uk/QuickGO/annotations?protein=P97784&geneProductId=UniProtKB:P97784)
41. [Preferential inhibition of BMAL2-CLOCK activity by PER2 reemphasizes its negative role and a positive role of BMAL2 in the circadian transcription](http://www.ebi.ac.uk/QuickGO/annotations?protein=P97784&geneProductId=UniProtKB:P97784)
42. [High-fat diet-induced hyperinsulinemia and tissue-specific insulin resistance in Cry-deficient mice](http://www.ebi.ac.uk/QuickGO/annotations?protein=P97784&geneProductId=UniProtKB:P97784)
43. [Gene model 129 (Gm129) encodes a novel transcriptional repressor that modulates circadian gene expression](http://www.ebi.ac.uk/QuickGO/annotations?protein=P97784&geneProductId=UniProtKB:P97784)
44. [Distinct and separable roles for endogenous CRY1 and CRY2 within the circadian molecular clockwork of the suprachiasmatic nucleus, as revealed by the Fbxl3(Afh) mutation.](http://www.ebi.ac.uk/QuickGO/annotations?protein=P97784&geneProductId=UniProtKB:P97784)
45. [Circadian clock feedback cycle through NAMPT-mediated NAD+ biosynthesis](http://www.ebi.ac.uk/QuickGO/annotations?protein=P97784&geneProductId=UniProtKB:P97784)
46. [Mammalian Cry1 and Cry2 are essential for maintenance of circadian rhythms](http://www.ebi.ac.uk/QuickGO/annotations?protein=P97784&geneProductId=UniProtKB:P97784)
47. [Cryptochromes are critical for the development of coherent circadian rhythms in the mouse suprachiasmatic nucleus](http://www.ebi.ac.uk/QuickGO/annotations?protein=P97784&geneProductId=UniProtKB:P97784)
48. [Delay in feedback repression by cryptochrome 1 is required for circadian clock function](http://www.ebi.ac.uk/QuickGO/annotations?protein=P97784&geneProductId=UniProtKB:P97784)
49. [Prokineticin 2 transmits the behavioural circadian rhythm of the suprachiasmatic nucleus](http://www.ebi.ac.uk/QuickGO/annotations?protein=P97784&geneProductId=UniProtKB:P97784)
50. [LARK activates posttranscriptional expression of an essential mammalian clock protein, PERIOD1.](http://www.ebi.ac.uk/QuickGO/annotations?protein=P97784&geneProductId=UniProtKB:P97784)