# Crumbs Dmel_CG6383

> protein found in Drosophila melanogaster

**Wikidata**: [Q29809512](https://www.wikidata.org/wiki/Q29809512)  
**Source**: https://4ort.xyz/entity/crumbs-dmel-cg6383


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P10040)
3. Q20641742
4. [DaPKC-dependent phosphorylation of Crumbs is required for epithelial cell polarity in Drosophila.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10040)
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10040)
6. [The apical transmembrane protein Crumbs functions as a tumor suppressor that regulates Hippo signaling by binding to Expanded](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10040)
7. [Role of the Crumbs complex in the regulation of junction formation in Drosophila and mammalian epithelial cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10040)
8. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10040)
9. [crumbs encodes an EGF-like protein expressed on apical membranes of Drosophila epithelial cells and required for organization of epithelia](http://www.ebi.ac.uk/QuickGO/annotations?protein=P10040&geneProductId=UniProtKB:P10040)
10. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P10040&geneProductId=UniProtKB:P10040)
11. [Apical, lateral, and basal polarization cues contribute to the development of the follicular epithelium during Drosophila oogenesis](http://www.ebi.ac.uk/QuickGO/annotations?protein=P10040&geneProductId=UniProtKB:P10040)
12. [The polarising role of cell adhesion molecules in early development](http://www.ebi.ac.uk/QuickGO/annotations?protein=P10040&geneProductId=UniProtKB:P10040)
13. [Laminin A-related domains in crb protein of Drosophila and their possible role in epithelial polarization](http://www.ebi.ac.uk/QuickGO/annotations?protein=P10040&geneProductId=UniProtKB:P10040)
14. [Crumbs regulates rhodopsin transport by interacting with and stabilizing myosin V](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10040)
15. [Function of Drosophila mob2 in photoreceptor morphogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10040)
16. [Epithelial Cell Polarity and Cell Junctions inDrosophila](http://www.ebi.ac.uk/QuickGO/annotations?protein=P10040&geneProductId=UniProtKB:P10040)
17. [Drosophila Stardust interacts with Crumbs to control polarity of epithelia but not neuroblasts.](http://www.ebi.ac.uk/QuickGO/annotations?protein=P10040&geneProductId=UniProtKB:P10040)
18. [Positive feedback and mutual antagonism combine to polarize Crumbs in the Drosophila follicle cell epithelium](http://www.ebi.ac.uk/QuickGO/annotations?protein=P10040&geneProductId=UniProtKB:P10040)
19. [Crumbs regulates rhodopsin transport by interacting with and stabilizing myosin V](http://www.ebi.ac.uk/QuickGO/annotations?protein=P10040&geneProductId=UniProtKB:P10040)
20. [Drosophila Stardust is a partner of Crumbs in the control of epithelial cell polarity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10040)
21. [The apical protein Apnoia interacts with Crumbs to regulate tracheal growth and inflation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10040)
22. [Positive feedback and mutual antagonism combine to polarize Crumbs in the Drosophila follicle cell epithelium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10040)
23. [A genome-wide resource for the analysis of protein localisation in Drosophila](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10040)
24. [Unique cell biological profiles of retinal disease-causing missense mutations in the polarity protein Crumbs](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10040)
25. [Apical, lateral, and basal polarization cues contribute to the development of the follicular epithelium during Drosophila oogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10040)
26. [Apicobasal polarization: epithelial form and function.](http://www.ebi.ac.uk/QuickGO/annotations?protein=P10040&geneProductId=UniProtKB:P10040)
27. [Membrane targeting.](http://www.ebi.ac.uk/QuickGO/annotations?protein=P10040&geneProductId=UniProtKB:P10040)
28. [Uncoupling apical constriction from tissue invagination](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10040)
29. [Dlg, Scribble and Lgl in cell polarity, cell proliferation and cancer](http://www.ebi.ac.uk/QuickGO/annotations?protein=P10040&geneProductId=UniProtKB:P10040)
30. [Crumbs is an essential regulator of cytoskeletal dynamics and cell-cell adhesion during dorsal closure in Drosophila.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10040)
31. [RNA interference screen to identify genes required for Drosophila embryonic nervous system development.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10040)
32. [Coordinated control of cell adhesion, polarity, and cytoskeleton underlies Hox-induced organogenesis in Drosophila.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10040)
33. [Tube morphogenesis: no pipe dream in Drosophila](http://www.ebi.ac.uk/QuickGO/annotations?protein=P10040&geneProductId=UniProtKB:P10040)
34. [Tube morphogenesis: closure, but many openings remain](http://www.ebi.ac.uk/QuickGO/annotations?protein=P10040&geneProductId=UniProtKB:P10040)
35. [Constructing an organ: the Drosophila salivary gland as a model for tube formation](http://www.ebi.ac.uk/QuickGO/annotations?protein=P10040&geneProductId=UniProtKB:P10040)
36. [Epithelial tube morphology is determined by the polarized growth and delivery of apical membrane](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10040)
37. [Crumbs stabilises epithelial polarity during tissue remodelling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10040)
38. [Endocytic control of epithelial polarity and proliferation in Drosophila](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10040)
39. [Drosophila Stardust interacts with Crumbs to control polarity of epithelia but not neuroblasts.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10040)
40. [The Ski2-family helicase Obelus regulates Crumbs alternative splicing and cell polarity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10040)
41. [Use of gain-of-function study to delineate the roles of crumbs in Drosophila eye development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10040)
42. [Time-specific regulation of airway clearance by the Drosophila J-domain transmembrane protein Wurst.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10040)
43. [The apical transmembrane protein Crumbs functions as a tumor suppressor that regulates Hippo signaling by binding to Expanded](http://www.ebi.ac.uk/QuickGO/annotations?protein=P10040&geneProductId=UniProtKB:P10040)
44. [Cell biology: a new view of photoreceptors](http://www.ebi.ac.uk/QuickGO/annotations?protein=P10040&geneProductId=UniProtKB:P10040)
45. [Use of gain-of-function study to delineate the roles of crumbs in Drosophila eye development](http://www.ebi.ac.uk/QuickGO/annotations?protein=P10040&geneProductId=UniProtKB:P10040)
46. [A new visualization approach for identifying mutations that affect differentiation and organization of the Drosophila ommatidia](http://www.ebi.ac.uk/QuickGO/annotations?protein=P10040&geneProductId=UniProtKB:P10040)
47. [The Hippo tumor-suppressor pathway regulates apical-domain size in parallel to tissue growth](http://www.ebi.ac.uk/QuickGO/annotations?protein=P10040&geneProductId=UniProtKB:P10040)
48. [Role of the Crumbs complex in the regulation of junction formation in Drosophila and mammalian epithelial cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=P10040&geneProductId=UniProtKB:P10040)
49. [Drosophila Crumbs is a positional cue in photoreceptor adherens junctions and rhabdomeres](http://www.ebi.ac.uk/QuickGO/annotations?protein=P10040&geneProductId=UniProtKB:P10040)
50. [Crumbs, the Drosophila homologue of human CRB1/RP12, is essential for photoreceptor morphogenesis](http://www.ebi.ac.uk/QuickGO/annotations?protein=P10040&geneProductId=UniProtKB:P10040)