Corticotropin releasing hormone receptor 1
type: Thing
description: mammalian protein found in Homo sapiens
additional property: PropertyValue
  property ID: P31
  value: protein
additional property: PropertyValue
  property ID: P129
  value: antalarmin
additional property: PropertyValue
  property ID: P352
  value: P34998
additional property: PropertyValue
  property ID: P361
  value: GPCR family 2, extracellular hormone receptor domain superfamily
additional property: PropertyValue
  property ID: P361
  value: GPCR, family 2, corticotropin releasing factor receptor, type 1
additional property: PropertyValue
  property ID: P361
  value: G protein-coupled recepteishon
additional property: PropertyValue
  property ID: P527
  value: GPCR, family 2, extracellular hormone receptor domain
additional property: PropertyValue
  property ID: P527
  value: GPCR, family 2, secretin-like, conserved site
additional property: PropertyValue
  property ID: P527
  value: GPCR, family 2-like
additional property: PropertyValue
  property ID: P637
  value: NP_001138618
additional property: PropertyValue
  property ID: P637
  value: NP_001138619
additional property: PropertyValue
  property ID: P637
  value: NP_001138620
additional property: PropertyValue
  property ID: P638
  value: 4K5Y
additional property: PropertyValue
  property ID: P638
  value: 3EHU
additional property: PropertyValue
  property ID: P638
  value: 2L27
additional property: PropertyValue
  property ID: P680
  value: G protein-coupled receptor activity
additional property: PropertyValue
  property ID: P680
  value: signal transducer activity
additional property: PropertyValue
  property ID: P680
  value: protein binding
additional property: PropertyValue
  property ID: P681
  value: integral component of membrane
additional property: PropertyValue
  property ID: P681
  value: endosome
additional property: PropertyValue
  property ID: P681
  value: membrane
additional property: PropertyValue
  property ID: P682
  value: corticotropin secretion
additional property: PropertyValue
  property ID: P682
  value: female pregnancy
additional property: PropertyValue
  property ID: P682
  value: activation of adenylate cyclase activity
additional property: PropertyValue
  property ID: P702
  value: CRHR1
additional property: PropertyValue
  property ID: P702
  value: LINC02210-CRHR1
additional property: PropertyValue
  property ID: P703
  value: Homo sapiens
additional property: PropertyValue
  property ID: P705
  value: ENSP00000484387
additional property: PropertyValue
  property ID: P705
  value: ENSP00000483802
additional property: PropertyValue
  property ID: P705
  value: ENSP00000463177
confidence:
  popularity graph score:
    score: 0.003
    score pct: 0
    tier: established
    components:
      sitelinks: 0
      sitelinks norm: 0.0
      unique citations: 19
      unique citations norm: 0.007
      monthly pageviews: 0
      monthly pageviews norm: 0.0
  sitelinks: 0
  unique citations: 19
  monthly pageviews: 0
  yearly pageviews: 0
  tier: established
claims:
  P31:
    value: Q8054
    source count: 1
    confidence: 0.2
    value label: protein
  P129:
    value: Q4770927
    source count: 1
    confidence: 0.2
    value label: antalarmin
  P352:
    value: P34998
    source count: 1
    confidence: 0.2
  P361:
    value: Q41797557
    source count: 1
    confidence: 0.2
    value label: GPCR family 2, extracellular hormone receptor domain superfamily
  P361:
    value: Q24785932
    source count: 1
    confidence: 0.2
    value label: GPCR, family 2, corticotropin releasing factor receptor, type 1
  P361:
    value: Q38173
    source count: 1
    confidence: 0.2
    value label: G protein-coupled recepteishon
  P361:
    value: Q423042
    source count: 1
    confidence: 0.2
    value label: membrane protein
  P361:
    value: Q83137599
    source count: 1
    confidence: 0.2
    value label: GPCR, family 2, extracellular hormone receptor domain, protein family
  P527:
    value: Q24741953
    source count: 1
    confidence: 0.2
    value label: GPCR, family 2, extracellular hormone receptor domain
  P527:
    value: Q24774228
    source count: 1
    confidence: 0.2
    value label: GPCR, family 2, secretin-like, conserved site
  P527:
    value: Q24766813
    source count: 1
    confidence: 0.2
    value label: GPCR, family 2-like
  P637:
    value: NP_001138618
    source count: 1
    confidence: 0.2
  P637:
    value: NP_001138619
    source count: 1
    confidence: 0.2
  P637:
    value: NP_001138620
    source count: 1
    confidence: 0.2
  P637:
    value: NP_001289947
    source count: 1
    confidence: 0.2
  P637:
    value: NP_001289949
    source count: 1
    confidence: 0.2
  P638:
    value: 4K5Y
    source count: 1
    confidence: 0.2
  P638:
    value: 3EHU
    source count: 1
    confidence: 0.2
  P638:
    value: 2L27
    source count: 1
    confidence: 0.2
  P638:
    value: 3EHS
    source count: 1
    confidence: 0.2
  P638:
    value: 3EHT
    source count: 1
    confidence: 0.2

value: Q14859545
source count: 2
confidence: 0.4
value label: G protein-coupled receptor activity

value: Q14820643
source count: 1
confidence: 0.2
value label: signal transducer activity

value: Q167149
source count: 3
confidence: 0.6
value label: protein binding

value: Q21110778
source count: 2
confidence: 0.4
value label: corticotrophin-releasing factor receptor activity

value: Q14864356
source count: 1
confidence: 0.2
value label: transmembrane signaling receptor activity

value: Q14327652
source count: 3
confidence: 0.6
value label: integral component of membrane

value: Q824237
source count: 1
confidence: 0.2
value label: endosome

value: Q14349455
source count: 2
confidence: 0.4
value label: membrane

value: Q21095104
source count: 1
confidence: 0.2
value label: intrinsic component of plasma membrane

value: Q29548
source count: 3
confidence: 0.6
value label: plasma membrane

value: Q14905245
source count: 1
confidence: 0.2
value label: corticotropin secretion

value: Q14819850
source count: 1
confidence: 0.2
value label: female pregnancy

value: Q14860503
source count: 1
confidence: 0.2
value label: activation of adenylate cyclase activity

value: Q21110777
source count: 1
confidence: 0.2
value label: regulation of adenylate cyclase activity involved in G protein-coupled receptor signaling pathway

value: Q14820580
source count: 1
confidence: 0.2
value label: cell surface receptor signaling pathway

value: Q5173298
source count: 1
confidence: 0.2
value label: CRHR1

value: Q27074532
source count: 1
confidence: 0.2
value label: LINC02210-CRHR1

value: Q15978631
source count: 1
confidence: 0.2
value label: Homo sapiens

value: ENSP00000484387
source count: 1
confidence: 0.2

value: ENSP00000483802
source count: 1
confidence: 0.2

value: ENSP00000463177
source count: 1
confidence: 0.2

value: ENSP00000484545
source count: 1
confidence: 0.2

value: ENSP00000488141
source count: 1
confidence: 0.2

value: 9.A.14.4.3
source count: 2
confidence: 0.4

source: GOA
stated in qid: Q28018111
retrieved: 2019-04-08

source: GOA
stated in qid: Q28018111
retrieved: 2018-01-01

source: Molecular recognition of corticotropin-releasing factor by its G-protein-coupled receptor CRFR1
stated in qid: Q24314090
retrieved: 2019-04-08

source: Corticotropin-Releasing Hormone Receptor Type 1 (CRHR1) Clustering with MAGUKs Is Mediated via Its C-Terminal PDZ Binding Motif
stated in qid: Q35767902
retrieved: 2019-04-08

source: Proteome-wide analysis of phospho-regulated PDZ domain interactions
stated in qid: Q56888773
retrieved: 2019-04-08

source: A novel spliced variant of the type 1 corticotropin-releasing hormone receptor with a deletion in the seventh transmembrane domain present in the human pregnant term myometrium and fetal membranes
stated in qid: Q22010931
retrieved: 2018-07-16

source: Activation of corticotropin-releasing factor receptor 1 selectively inhibits CaV3.2 T-type calcium channels
stated in qid: Q24316197
retrieved: 2018-07-16

source: A novel spliced variant of the type 1 corticotropin-releasing hormone receptor with a deletion in the seventh transmembrane domain present in the human pregnant term myometrium and fetal membranes
stated in qid: Q22010931
retrieved: 2019-04-08

source: Activation of corticotropin-releasing factor receptor 1 selectively inhibits CaV3.2 T-type calcium channels
stated in qid: Q24316197
retrieved: 2019-04-08

source: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
stated in qid: Q34211397
retrieved: 2019-04-08

source: Structure of class B GPCR corticotropin-releasing factor receptor 1
stated in qid: Q24309523
retrieved: 2019-04-08

source: Expression cloning of a human corticotropin-releasing-factor receptor
stated in qid: Q24311371
retrieved: 2019-04-08

source: A placental clock controlling the length of human pregnancy
stated in qid: Q24313192
retrieved: 2019-04-08

source: InterPro Release 71.0
stated in qid: Q58943792

source: UniProt
stated in qid: Q905695
retrieved: 2019-11-13

source: IUPHAR/BPS Guide to PHARMACOLOGY
stated in qid: Q17091219
retrieved: 2016-04-27

source: Q20641742
stated in qid: Q20641742
retrieved: 2020-05-30

source: Transporter Classification database
stated in qid: Q142667
retrieved: 2020-03-13

source: Ensembl Release 99
stated in qid: Q83867711

wikidata id: Q22677568
domain: protein
level: standard
html url: https://4ort.xyz/entity/corticotropin-releasing-hormone-receptor-1-q22677568
markdown url: https://4ort.xyz/entity/corticotropin-releasing-hormone-receptor-1-q22677568.md
facts url summary: https://4ort.xyz/entity/corticotropin-releasing-hormone-receptor-1-q22677568/facts.json
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facts url full: https://4ort.xyz/entity/corticotropin-releasing-hormone-receptor-1-q22677568/facts.json
data source: Wikidata (CC0 / public domain)
license: https://creativecommons.org/publicdomain/zero/1.0/
api version: v1
served at: 2026-08-02T08:25:29.117151Z
entity updated at: 2026-05-03T18:28:36.114423+00:00Z
entity created at: 2026-05-03T15:26:17.974639+00:00Z