# Corticotropin releasing hormone

> mammalian protein found in Rattus norvegicus

**Wikidata**: [Q28561034](https://www.wikidata.org/wiki/Q28561034)  
**Source**: https://4ort.xyz/entity/corticotropin-releasing-hormone-q28561034


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P01143)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01143)
5. [A single amino acid serves as an affinity switch between the receptor and the binding protein of corticotropin-releasing factor: implications for the design of agonists and antagonists](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01143)
6. [Urocortin, a mammalian neuropeptide related to fish urotensin I and to corticotropin-releasing factor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01143)
7. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01143)
8. [Alterations in central neuropeptide expression, release, and receptor binding in rats bred for high anxiety: critical role of vasopressin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01143)
9. [Three-amino acid motifs of urocortin II and III determine their CRF receptor subtype selectivity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01143)
10. [Hypophysiotropic thyrotropin-releasing hormone and corticotropin-releasing hormone neurons of the rat contain vesicular glutamate transporter-2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01143)
11. [Ferulic acid-induced anti-depression and prokinetics similar to Chaihu-Shugan-San via polypharmacology](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01143)
12. [Stress and glucocorticoids regulated corticotropin releasing factor in rat prefrontal cortex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01143)
13. [Corticotropin releasing factor-distribution in rat intestine and role in neuroprotection](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01143)
14. [Distribution of corticotropin-releasing factor binding protein-immunoreactivity in the rat hypothalamus: association with corticotropin-releasing factor-, urocortin 1- and vimentin-immunoreactive fibres](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01143)
15. [Aging associated changes in amygdalar corticotropin-releasing hormone (CRH) and CRH-binding protein in Fischer 344 rats](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01143)
16. [CRF1-R activation of the dynorphin/kappa opioid system in the mouse basolateral amygdala mediates anxiety-like behavior](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01143)
17. [Corticotropin-releasing factor requires CRF binding protein to potentiate NMDA receptors via CRF receptor 2 in dopamine neurons](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01143)
18. [Modulation of social learning in rats by brain corticotropin-releasing factor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01143)
19. [CRFR1 is expressed on pancreatic beta cells, promotes beta cell proliferation, and potentiates insulin secretion in a glucose-dependent manner](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01143)
20. [Modulation of learning and anxiety by corticotropin-releasing factor (CRF) and stress: differential roles of CRF receptors 1 and 2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01143)
21. [Corticotropin-releasing hormone induces Fas ligand production and apoptosis in PC12 cells via activation of p38 mitogen-activated protein kinase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01143)
22. [Role of urocortin 2 secreted by the pituitary in the stress-induced suppression of luteinizing hormone secretion in rats](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01143)
23. [Role of corticotrophin-releasing hormone in the impairment of counterregulatory responses to hypoglycemia](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01143)
24. [Effect of lamotrigine and carbamazepine on corticotropin-releasing factor-associated serotonergic transmission in rat dorsal raphe nucleus](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01143)
25. [Corticotrophin-releasing factor alters the timing of puberty in the female rat](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01143)
26. [Inhibition of food intake induced by acute stress in rats is due to satiation effects](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01143)
27. [Rapid stress-induced elevations in corticotropin-releasing hormone mRNA in rat central amygdala nucleus and hypothalamic paraventricular nucleus: An in situ hybridization analysis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01143)
28. [Extended access cocaine self‐administration differentially activates dorsal raphe and amygdala corticotropin‐releasing factor systems in rats](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01143)
29. [Influence of electroacupuncture on efficacy of estrogen in regulating hypothalamic reproductive endocrine activity in rats](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01143)
30. [Effects of acute ethanol on corticotropin-releasing hormone and β-endorphin systems at the level of the rat central amygdala](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01143)
31. [Acute ether stress differentially affects corticotropin-releasing factor and urocortin 1 in the Brattleboro rat](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01143)
32. [Differential responses of corticotropin-releasing factor and urocortin 1 to acute pain stress in the rat brain](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01143)
33. [Hypothalamic cocaine- and amphetamine-regulated transcript and corticotrophin releasing factor neurons are stimulated by extracellular volume and osmotic changes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01143)
34. [Roles of two subtypes of corticotrophin‐releasing factor receptor in the corticostriatal long‐term potentiation under cocaine withdrawal condition](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01143)
35. [Pathways involved in gut mucosal barrier dysfunction induced in adult rats by maternal deprivation: corticotrophin-releasing factor and nerve growth factor interplay](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01143)
36. [Corticotropin-releasing factor (CRF) and related peptides confer neuroprotection via type 1 CRF receptors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01143)
37. [Effects of chronic cocaine exposure on corticotropin-releasing hormone binding protein in the central nucleus of the amygdala and bed nucleus of the stria terminalis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01143)
38. [Modulation of Ca2+ influx by corticotropin-releasing factor (CRF) family of peptides via CRF receptors in rat pancreatic beta-cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01143)
39. ensembl Release 106