# Copper metabolism domain containing 1

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21113001](https://www.wikidata.org/wiki/Q21113001)  
**Source**: https://4ort.xyz/entity/copper-metabolism-domain-containing-1


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q8N668)
3. Q20641742
4. [COMMD proteins, a novel family of structural and functional homologs of MURR1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N668)
5. [Characterization and copper binding properties of human COMMD1 (MURR1)](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N668)
6. [COMMD1 forms oligomeric complexes targeted to the endocytic membranes via specific interactions with phosphatidylinositol 4,5-bisphosphate](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N668)
7. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N668)
8. [A novel role for XIAP in copper homeostasis through regulation of MURR1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N668)
9. [The copper-transporting capacity of ATP7A mutants associated with Menkes disease is ameliorated by COMMD1 as a result of improved protein expression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N668)
10. [Tumor suppressor ARF promotes non-classic proteasome-independent polyubiquitination of COMMD1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N668)
11. [CCDC22 deficiency in humans blunts activation of proinflammatory NF-κB signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N668)
12. [A novel nuclear complex of DRR1, F-actin and COMMD1 involved in NF-κB degradation and cell growth suppression in neuroblastoma](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N668)
13. [COMMD1 downregulates the epithelial sodium channel through Nedd4–2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N668)
14. [Retriever is a multiprotein complex for retromer-independent endosomal cargo recycling.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N668)
15. [COMMD1 is linked to the WASH complex and regulates endosomal trafficking of the copper transporter ATP7A](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N668)
16. [COMMD1 promotes the ubiquitination of NF-kappaB subunits through a cullin-containing ubiquitin ligase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N668)
17. [COMMD1 (Copper Metabolism MURR1 Domain-containing Protein 1) Regulates Cullin RING Ligases by Preventing CAND1 (Cullin-associated Nedd8-dissociated Protein 1) Binding](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N668)
18. [The copper toxicosis gene product Murr1 directly interacts with the Wilson disease protein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N668)
19. [A proteome-scale map of the human interactome network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N668)
20. [A human interactome in three quantitative dimensions organized by stoichiometries and abundances](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N668)
21. [The gene product Murr1 restricts HIV-1 replication in resting CD4+ lymphocytes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N668)
22. [Identification of Murr1 as a regulator of the human delta epithelial sodium channel](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N668)
23. [COMMD1 regulates the delta epithelial sodium channel (δENaC) through trafficking and ubiquitination](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N668)
24. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8N668&geneProductId=UniProtKB:Q8N668)
25. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N668)
26. [COMMD1 downregulates the epithelial sodium channel through Nedd4–2](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8N668&geneProductId=UniProtKB:Q8N668)
27. [Identification of Murr1 as a regulator of the human delta epithelial sodium channel](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8N668&geneProductId=UniProtKB:Q8N668)
28. [COMMD1 regulates the delta epithelial sodium channel (δENaC) through trafficking and ubiquitination](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8N668&geneProductId=UniProtKB:Q8N668)
29. [COMMD1 promotes the ubiquitination of NF-kappaB subunits through a cullin-containing ubiquitin ligase](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8N668&geneProductId=UniProtKB:Q8N668)
30. [Characterization of COMMD protein-protein interactions in NF-kappaB signalling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N668)
31. [A novel role for XIAP in copper homeostasis through regulation of MURR1](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8N668&geneProductId=UniProtKB:Q8N668)
32. Ensembl Release 99