# Contingency and entrenchment in protein evolution under purifying selection

> Research article (Proceedings of the National Academy of Sciences, 2015) · cited 214× · AI/ML

**Wikidata**: [openalex:W1512750650](https://www.wikidata.org/wiki/openalex:W1512750650)  
**Source**: https://4ort.xyz/entity/contingency-and-entrenchment-in-protein-evolution-under-purifying-selection